A61K31/231

NANOPARTICLE DELIVERY SYSTEM FOR TARGETED ANTI-OBESITY TREATMENT
20210346499 · 2021-11-11 ·

A magnetic nanoparticle including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical can include a core region having a magnetic nanoparticle (MNPs) and a TRPV1 protein agonist. Further, an exterior coating comprising a polymer can be formed around the core region. The magnetically responsive pharmaceutical can be administered to a recipient and directed to a target region using an external magnetic field.

NANOPARTICLE DELIVERY SYSTEM FOR TARGETED ANTI-OBESITY TREATMENT
20210346499 · 2021-11-11 ·

A magnetic nanoparticle including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical can include a core region having a magnetic nanoparticle (MNPs) and a TRPV1 protein agonist. Further, an exterior coating comprising a polymer can be formed around the core region. The magnetically responsive pharmaceutical can be administered to a recipient and directed to a target region using an external magnetic field.

COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND
20210346346 · 2021-11-11 · ·

Disclosed herein are compositions comprising a serotonergic tryptamine compound, combinations thereof, and methods of using them for treating and preventing a variety of human conditions. In one embodiment, disclosed herein are new compositions and methods which comprise a therapeutically effective amount of a first purified psilocybin derivative and a therapeutically effective amount of a second compound. The second compound is selected from the group consisting of a second purified psilocybin derivative, a purified terpene, a serotonergic drug, an adrenergic drug, a dopaminergic drug, a purified erinacine, and a purified hericenone.

METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER
20220125882 · 2022-04-28 ·

In one aspect, methods and compositions are provided for treating a neoplasia such as a solid tumor, the methods and composition comprising a) a granulocyte colony-stimulating factor (G-CSF) compound; and b) a monoacetyl diacylglycerol compound such as 1-palmitoyl-2-linoleoyl-3-acetylglycerol (PLAG).

METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER
20220125882 · 2022-04-28 ·

In one aspect, methods and compositions are provided for treating a neoplasia such as a solid tumor, the methods and composition comprising a) a granulocyte colony-stimulating factor (G-CSF) compound; and b) a monoacetyl diacylglycerol compound such as 1-palmitoyl-2-linoleoyl-3-acetylglycerol (PLAG).

METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER
20220125882 · 2022-04-28 ·

In one aspect, methods and compositions are provided for treating a neoplasia such as a solid tumor, the methods and composition comprising a) a granulocyte colony-stimulating factor (G-CSF) compound; and b) a monoacetyl diacylglycerol compound such as 1-palmitoyl-2-linoleoyl-3-acetylglycerol (PLAG).

USE OF POLYOL FATTY ESTER COMPOSITIONS AND PRODUCTS FOR MINIMIZING EXPOSURE TO A NOXIOUS SUBSTANCE
20210338625 · 2021-11-04 ·

Method for minimizing exposure to a noxious substance, the method comprising the step of administering a spray composition to a surface or applying a wipe to a surface contaminated by the noxious substance, wherein the composition in the spray or impregnated into the wipe comprises a polyol fatty ester.

USE OF POLYOL FATTY ESTER COMPOSITIONS AND PRODUCTS FOR MINIMIZING EXPOSURE TO A NOXIOUS SUBSTANCE
20210338625 · 2021-11-04 ·

Method for minimizing exposure to a noxious substance, the method comprising the step of administering a spray composition to a surface or applying a wipe to a surface contaminated by the noxious substance, wherein the composition in the spray or impregnated into the wipe comprises a polyol fatty ester.

Digestive Lipase Activity Inhibitor, Blood Triglyceride Concentration Increase Inhibitor, and Fat Absorption Inhibitor

The present invention relates to a digestive lipase activity inhibitor containing, as an active ingredient, at least one selected from the group consisting of linoleic acid and oleic acid.

Application of trans-1,3-dilinolein in the preparation of medicaments for treating gastric cancer, stomachic tonic, health products and foods
11744818 · 2023-09-05 · ·

Some embodiments of the disclosure provide new uses of trans-1,3-dilinolein as medicaments and food. In an embodiment, an application of trans-1,3-dilinolein in the preparation of stomachic tonic and an application thereof include the preparation of medicaments for treating gastric cancer. Cell experiments show that trans-1,3-dilinolein promotes the proliferation of human gastric mucosal epithelial cell line GES-1 under normal oxygen and hypoxic conditions and it has concentration-dependent killing effect on human gastric cancer cell line HGC-27 and killing effect on hypoxic gastric cancer cells. At a concentration of 300 μm and more, trans-1,3-dilinolein kills gastric cancer cells significantly and the killing effect becomes more significant under hypoxic conditions.