A61K31/4422

COMPOSITIONS CONTAINING ANDROGEN RECEPTOR ANTAGONISTS
20220313704 · 2022-10-06 ·

Compositions and methods for treating hair loss, for example hair loss associated with acne related to hormonal conditions, using topically administered androgen receptor antagonists are described herein. The androgen receptor antagonist may be one selected from cyproterone acetate, flutamide, RU-58841, bicalutamide, nilutamide, canrenone, spironolactone, progesterone, 4MA, ketoconazole, cimetidine, and derivatives and combinations thereof.

COMPOSITIONS CONTAINING ANDROGEN RECEPTOR ANTAGONISTS
20220313704 · 2022-10-06 ·

Compositions and methods for treating hair loss, for example hair loss associated with acne related to hormonal conditions, using topically administered androgen receptor antagonists are described herein. The androgen receptor antagonist may be one selected from cyproterone acetate, flutamide, RU-58841, bicalutamide, nilutamide, canrenone, spironolactone, progesterone, 4MA, ketoconazole, cimetidine, and derivatives and combinations thereof.

PHARMACEUTICAL UNIT DOSE SYSTEMS FOR ORAL DRY SOLUTION AND SUSPENSION
20220257469 · 2022-08-18 · ·

This disclosure provides a pharmaceutical unit dose system. The unit dose system includes a unit-of-use self-dispersing dry composition for oral suspension. Also provided is a method for preparing a single unit dose of a dry pharmaceutical composition for oral administration. The unit dose system is advantageous in the convenience of use, dosing accuracy, long term storage, suspension uniformity over conventional multidose powder composition for oral suspension.

Methods and products for preventing and/or treating microorganism infections comprising iron chelators and non-iron porphyrins

The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.

Methods and products for preventing and/or treating microorganism infections comprising iron chelators and non-iron porphyrins

The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.

Methods and products for preventing and/or treating microorganism infections comprising iron chelators and non-iron porphyrins

The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.

Methods of treating amyloid-beta peptide diseases
20220110902 · 2022-04-14 ·

The present invention is directed to a method of treating an amyloid-β peptide disease in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a compound that enhances mitochondrial proteostasis.

Non-Aqueous Liquid Nimodipine Compositions
20220110925 · 2022-04-14 ·

Non-aqueous liquid compositions comprising nimodipine having improved stability over aqueous compositions comprising nimodipine are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the non-aqueous liquid compositions of the present invention are also detailed herein.

Non-Aqueous Liquid Nimodipine Compositions
20220110925 · 2022-04-14 ·

Non-aqueous liquid compositions comprising nimodipine having improved stability over aqueous compositions comprising nimodipine are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the non-aqueous liquid compositions of the present invention are also detailed herein.

Non-Aqueous Liquid Nimodipine Compositions
20220110926 · 2022-04-14 ·

Non-aqueous liquid compositions comprising nimodipine having improved stability over aqueous compositions comprising nimodipine are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the non-aqueous liquid compositions of the present invention are also detailed herein.