A61K38/1735

COMPOSITIONS FROM GASTROINTESTINAL TRACT MUCINS, AND USES THEREOF
20230295256 · 2023-09-21 ·

Disclosed are compositions comprising glycopeptides obtained from gastrointestinal mucins that have superior microbiota affects, and methods of manufacture and use thereof. Such compositions are advantageous for pharmaceutical, food stuff and pet food applications.

EGG PROTEIN FORMULATIONS AND METHODS OF MANUFACTURE THEREOF
20230158081 · 2023-05-25 ·

The present technology relates generally to formulations comprising egg white protein, methods of manufacturing egg protein formulations and uses for egg protein formulations. In particular, several embodiments are directed to egg protein formulations for oral administration in immunotherapy of subjects affected by egg allergies.

MUCIN ISOFORMS IN DISEASES CHARACTERIZED BY BARRIER DYSFUNCTION

The present invention relates to the field of mucin isoforms, more in particular for use in the diagnosis, monitoring, prevention and/or treatment of a disease characterized by barrier dysfunction, such as but not limited to a gastrointestinal disorder (e.g. Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), cancer, gastro-intestinal infections, obesitas, non-alcoholic fatty liver disease (NAFLD)), neurodegenerative disorders, respiratory infections, . . . In a specific embodiment, said mucin isoform is selected from the list comprising: MUC1 isoforms and MUC13 isoforms.

NME INHIBITORS AND METHODS OF USING NME INHIBITORS

The present application discloses inhibitors of NME family of proteins.

MICROBIOME MARKERS AND USES THEREOF
20220240543 · 2022-08-04 ·

Bacterial species acting as biomarkers for obesity in domesticated cats and/or dogs are disclosed herein. Also disclosed are methods for diagnosing and/or treating cats and/or dogs having obesity or a predisposition to obesity as well as methods of screening for agents to treat or prevent obesity.

NME INHIBITORS AND METHODS OF USING NME INHIBITORS

The present application discloses inhibitors of NME family of proteins.

COMPOSITIONS DERIVED FROM GASTROINTESTINAL TRACT MUCINS
20220104528 · 2022-04-07 ·

Disclosed are methods and compositions comprising glycopeptides obtained from gastrointestinal sources that have superior microbiota effects. Such compositions are advantageous for food stuff, including infant formulations.

COMPOSITIONS DERIVED FROM GASTROINTESTINAL TRACT MUCINS
20220104528 · 2022-04-07 ·

Disclosed are methods and compositions comprising glycopeptides obtained from gastrointestinal sources that have superior microbiota effects. Such compositions are advantageous for food stuff, including infant formulations.

Pharmaceutical composition containing a stabilised mRNA optimised for translation in its coding regions

The present invention relates to a pharmaceutical composition comprising a modified mRNA that is stabilised by sequence modifications and optimised for translation. The pharmaceutical composition according to the invention is particularly well suited for use as an inoculating agent, as well as a therapeutic agent for tissue regeneration. In addition, a process is described for determining sequence modifications that promote stabilisation and translational efficiency of modified mRNA of the invention.

Systems, devices, and methods for treating a pulmonary disorder with an agent
11103684 · 2021-08-31 · ·

A medication delivery device for treatment of a pulmonary disorder in a patient includes an elongate member, an expandable member is coupled to a distal end of the elongate member, and an agent delivery portion coupled to an external surface of the expandable member. The agent delivery portion includes an agent that disrupts nerve activity.