Bacterial species acting as biomarkers for obesity in domesticated cats and/or dogs are disclosed herein. Also disclosed are methods for diagnosing and/or treating cats and/or dogs having obesity or a predisposition to obesity as well as methods of screening for agents to treat or prevent obesity.

The present invention provides pharmaceutical compositions and methods to treat inflammatory joint diseases and decrease cartilage degradation. In certain embodiments, the pharmaceutical compositions of the invention comprise an agent that binds to a -2,3-sialic acid transmembrane glycoprotein.

The present invention relates to a pharmaceutical composition comprising a modified mRNA that is stabilized by sequence modifications and optimized for translation. The pharmaceutical composition according to the invention is particularly well suited for use as an inoculating agent, as well as a therapeutic agent for tissue regeneration. In addition, a process is described for determining sequence modifications that promote stabilization and translational efficiency of modified mRNA of the invention.

Disclosed herein is mucin-coated silica, compositions comprising the same, and methods of promoting the aggregation and/or clearance of oral bacteria using such compositions.

The present application discloses inhibitors of NME family of proteins.

The present invention relates to methods and compositions for modifying mucous membranes. In particular, the present invention relates to treating diseases associated with mucous membranes by changing the intrinsic chemical composition and/or physical features of a target mucous membrane.

The present invention relates to methods and compositions for modifying mucous membranes. In particular, the present invention relates to treating diseases associated with mucous membranes by changing the intrinsic chemical composition and/or physical features of a target mucous membrane.

The present invention relates to the use of secreted proteins from mesenchymal stem cells and other cells for the treatment of myocardial infarction. In particular, the invention provides compositions and methods based on secreted proteins from mesenchymal stem cells and the genes encoding them.

Provided herein are methods and compositions for treating a tumor or increasing the anti-cancer effectiveness of an immune checkpoint inhibitor using glycopeptide containing compositions.

Provided herein are methods and compositions for treating a tumor or increasing the anti-cancer effectiveness of an immune checkpoint inhibitor using glycopeptide containing compositions.