A hemodialysis system includes a blood treatment machine, a blood pump housed by the blood treatment machine, a first dialysate pump housed by the blood treatment machine, a second dialysate pump housed by the blood treatment machine; and a fluid cassette including an upper portion and a lower portion. The fluid cassette further includes a blood pumping tube extending from the upper portion to the lower portion of the fluid cassette, a first dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette, and a second dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette.

The present invention concerns a method for testing the rigidity of a particular disposable for volumetric balancing, for a blood treatment device, comprised of the following steps: filling the disposable or portion thereof with a liquid, enclosing the filled liquid, so that a certain volume of liquid is present in the disposable unit or the portion thereof, supplying and/or discharging a certain volume of liquid, and measuring the change in pressure caused by the supply and/or discharge of the volume of liquid. The present invention further concerns a blood treatment device.

A method for priming a hemodialysis treatment includes: providing a disposable cassette including at least a portion of a dialysate circuit and at least a portion of a blood circuit; placing a dialyzer in fluid communication with the dialysate circuit via a to-dialyzer dialysate line and a from-dialyzer dialysate line; placing the dialyzer in fluid communication with the blood circuit via an arterial blood line and a venous blood line; placing a source of dialysis fluid in fluid communication with the dialyzer; priming the dialysate circuit with dialysis fluid from the source while both the to-dialyzer dialysate line and the from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and priming the blood circuit with dialysis fluid from the source by actuating at least one valve provided by the disposable cassette.

A renal failure therapy machine includes a blood cleaning filter, a dialysis fluid circuit including a balance chamber, the balance chamber including a fresh dialysis fluid compartment configured to send fresh dialysis fluid to the blood cleaning filter and a used dialysis fluid compartment configured to receive used dialysis fluid from the blood cleaning filter, a fresh dialysis fluid line in fluid communication with the fresh dialysis fluid compartment of the balance chamber and the blood cleaning filter, and a flow restrictor in fluid communication with the blood cleaning filter, the flow restrictor configured to cause fresh dialysis fluid delivered from the fresh dialysis fluid compartment, through the fresh dialysis fluid line, to the blood cleaning filter to be pressurized so that a first amount of the fresh dialysis fluid performs convective clearance and a second amount of the fresh dialysis fluid performs diffusive clearance.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

A balancing device and a method for balancing between an inflow into a blood treatment unit of a medical treatment device and an outflow out of the blood treatment unit are disclosed. The balancing device: includes a balancing unit, which has at least one exchange vessel; means for conveying fluid into and/or out of the exchange vessel and means for interrupting the inflow of fluid into the exchange vessel and/or the outflow of fluid out of the exchange vessel; and a control unit for controlling the means for conveying fluid and the means for interrupting the inflow and/or outflow of fluid by an equalization of pressure between a first work cycle and a second work cycle.

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.

A dialysis system includes an on-line dialysate generator, a first dialysate pump in fluid communication with the on-line dialysate generator, and a second dialysate pump in fluid communication with the on-line dialysate generator. The dialysis system also includes a dialyzer in fluid communication with the first and second dialysate pumps. The dialysis system further includes a first valve located between the first dialysate pump and the dialyzer and a second valve located between the second dialysate pump and the dialyzer. The dialysis system is configured to alternate pumping of dialysate from the first and second dialysate pumps to the dialyzer using the first and second valves.

The disclosure relates to a dialysis system comprising a dialysate side and a blood side. In particular, and for example, in some embodiments, a dialysis system is provided and comprises a dialyzer including and a blood filter configured to divide the dialyzer and dialysis system into a blood side and a dialysate side. The blood side includes a blood circuit comprising a blood pump, a blood removal line, a blood return line, and a blood return line valve (BRV). The blood removal line and blood return line converge to a single venous access line in blood communication with a patient. The dialysate side includes a dialysate fluid circuit comprising first and second pump chambers each having a plurality of respective valves configurable to enable or prevent fluid communication with both the dialyser side of the dialyser and a drain. Each of the first and second pump chambers are configurable, based on the configurations of the valves, to comprise a blood accumulation chamber.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.