The invention relates to a device (10) for degassing dialysis concentrates for automatic density measurement in mixing systems, comprising: an overflowable filter element (53), wherein the overflowable filter element (53) converts gas bubble-laden dialysis concentrate at the input end into a gas bubble-free dialysis concentrate at the output end. The invention also relates to a mixing system (M) having a device (10) according to the invention and a method for degassing dialysis concentrates for automatic density measurement in mixing systems (M), comprising the steps: Introducing (100) the dialysis concentrate laden with gas bubbles into the overflowable filter element (53), Filtering out (200) gases, Diverting (300) the gas bubble-free dialysis concentrate, Measuring (400) the density of the gas bubble-free dialysis concentrate.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

An extracorporeal blood treatment apparatus comprises a blood treatment device (2), an extracorporeal blood circuit, a blood pump (8) configured to be coupled to a blood withdrawal line (6) of the extracorporeal blood circuit. A closed fluid line (10) is connected to an inlet port (4a) and to an outlet port (4b) of a fluid chamber (4) of the blood treatment device (2), wherein the closed fluid line (10) together with the fluid chamber (4) forms a recirculation loop. An evacuation line (15) departs from the closed fluid line (10). A warming device (13) and a recirculation pump (17) are coupled or configured to be coupled to the closed fluid line (10). At least one temperature sensor (22) is operative on the extracorporeal blood circuit and it is configured to sense a blood temperature (Tb). A control unit (25), connected to the warming device (13), to the recirculation pump (17) and to the temperature sensor (22), is configured to execute the following procedure: receiving from the temperature sensor (22) at least a signal correlated to the blood temperature (Tb); adjusting the blood temperature (Tb) by controlling at least one of the warming device (13) and the recirculation pump (17).

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

The present invention relates to a dialysis machine having an extracorporeal blood system; a dialysis fluid system having a dialyzer; having a control unit, wherein the dialysis machine furthermore comprises a balancing chamber having two balancing chamber halves for a balanced infeed and draining of dialysis fluid to and from the dialyzer, wherein a line is provided through which the dialysis fluid is conducted to the balancing chamber, and wherein a mixing chamber is provided in which the fresh dialysis fluid or a component thereof is located and which is directly or indirectly connected to a de-airing line closable by a valve; wherein the dialysis machine has a control unit that is configured such that the control unit opens and closes the valve once, or a number of times, in the operating state of the special air separation of the dialysis machine when the balancing chamber half of the balancing chamber in fluid communication with the named line is in its high-pressure phase.

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing and including a reusable pump body that accepts PD fluid for pumping; a dialysis fluid inline heater housed by the housing and including a reusable heater body that accepts PD fluid for heating; at least one reusable PD fluid line extending from the housing; at least one disinfection connector supported by the housing and configured to accept one of the at least one reusable PD fluid line; and a control unit configured to run a disinfection sequence after a PD treatment, wherein each of the at least one reusable PD fluid line is connected to one of the at least one disinfection connectors, and wherein at least one of the dialysis fluid pump or the dialysis fluid inline heater is actuated by the control unit during the disinfection sequence.

In some examples, a connector includes a plug configured to mechanically couple with a socket to establish fluid communication from a first conduit to a second conduit. The plug is configured to mechanically engage the first conduit and the socket is configured to mechanically engage the second conduit. In examples, the plug is configured to insert into a socket well of the socket. The connector includes a clamp head configured to mechanically engage the plug when the plug mechanically couples with the socket. The clamp head is configured to mechanically engage the plug to help sustain the mechanical coupling of the plug and the socket. In some examples, the connector may include an output device configured to provide an output indicating when the plug is mechanically coupled with the socket.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Devices, systems, and methods for high capacity degassing of dissolved gases and gas bubbles from fluid such as a dialysate are provided. The devices, systems, and methods can include a degassing vessel with at least two degassing chambers. The fluid can be degassed in a first degassing chamber and recirculated through a second recirculating degassing chamber to remove a desired amount of gas such as carbon dioxide.