The invention relates to a dialysis machine comprising an apparatus for the treating of fluids, in particular for the treating of water for the dialysis, wherein the apparatus comprises one or more hollow fiber membrane filters, fluid lines, one or more sampling points and valve connections, wherein the apparatus is configured such that contaminants can concentrate in a first hollow fiber membrane filter and conclusions can be drawn as to the contamination of the provided fluid, in particular water, from an analysis value determined from samples of the concentrated contaminants. The invention further relates to a method for monitoring the apparatus for treating fluids, in particular water, for contamination.

A method and apparatus for evaluating a condition of a water purification system (40, 110) comprising a water purification apparatus (110) arranged to output purified water through an outlet (128) and through at least one sterilizing grade filter (70a, 70b) of a line set (40) fluidly connected to the outlet (128), the method comprises: monitoring a flow rate (S1) correlated with the flow rate of the purified water flowing through the at least one sterilizing grade filter (70a, 70b); monitoring a pressure (S2) correlated with the pressure of the purified water flowing to the at least one sterilizing grade filter (70a, 70b); and evaluating (S3) a condition of the water purification system based on a relationship between the monitored flow rate and the monitored pressure.

The reverse osmosis system with at least one high pressure pump, which supplies untreated water to at least one module pipe, in which a membrane with a permeate collecting pipe is arranged, includes a permeate outlet of the at least one module pipe that is connected by means of a first conduit to a permeate tank, which is in communication by means of a further conduit, connected into which there is a permeate supply pump, with a loop feed line, to which a plurality of dialysis devices are connected and that branching off from the first conduit there is a bypass conduit, which discharges into the further conduit downstream of the permeate tank and the permeate supply pump.

A peritoneal dialysis device includes a disposable tubing set that includes a fill line with a patient access connector at one end and a dialysis fluid receiving end opposite the patient access connector end. The device also includes a fill-side pressure measuring sensor attached at the fill end and forming a disposable component of the tubing set and a patient-side pressure measuring sensor located at the fluid receiving end. The patient-side and fill-side pressure measuring sensors are adapted for measuring pressure in the fill line at the respective ends thereof. The device also includes a controller configured to regulate a rate of flow in the fill line responsively to a signal from the at least the patient-side pressure measuring sensor.

A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor.

A portable device for removal of metabolic waste from the blood of patient having kidney disease or in need of hemodialysis is provided. Methods of hemodialysis employing the portable device beneficially obtain a dialysate by electrokinetic means from excess fluid in the peripheral blood of the patient in need thereof. The methods employ a branched microfluidic channel for the use of ion concentration polarization to separate charged from neutral species in blood to obtain the dialysate for undergoing hemodialysis. Beneficially the methods and device are resistant to biofouling, remove the need for a dialysate and/or dialysate reservoir, and provide a disposable, wearable device.

A dialysis system includes a sorbent device positioned along a fluid circuit for regenerating dialysate during a dialysis treatment carried out at the dialysis system, a filter coupled to an outlet of the sorbent device such the any fluid flowing through the sorbent device must first flow through the filter before reentering the fluid circuit, and a pump positioned downstream of the filter along the fluid circuit. The pump is operable between first and second dialysis treatments carried out at the dialysis system to circulate a fluid through the sorbent device to prevent matter within the sorbent device from solidifying and circulate the fluid through the filter to remove contaminants from the fluid.

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

The reverse osmosis system with at least one high pressure pump, which supplies untreated water to at least one module pipe, in which a membrane with a permeate collecting pipe is arranged, includes a permeate outlet of the at least one module pipe that is connected by means of a first conduit to a permeate tank, which is in communication by means of a further conduit, connected into which there is a permeate supply pump, with a loop feed line, to which a plurality of dialysis devices are connected and that branching off from the first conduit there is a bypass conduit, which discharges into the further conduit downstream of the permeate tank and the permeate supply pump.

A dialysis system is provided that includes a dialysis machine and a potassium sensing device that is configured to measure the concentration of potassium in the patient's blood, in spent dialysate resulting from treating the patient, or in both. The potassium sensing device can be configured to generate a sensed value of the concentration of potassium. A control and computing unit, including a processor and a memory, is configured to receive the sensed value, compare the value with one or more values stored in the memory, and generate a control signal based on the comparison. A potassium infusion circuit uses the control signal to infuse supplemental potassium solution into the treatment dialysate, a replacement fluid, or both. The memory can include stored patient-historical and population data.