The present invention relates to a dialysis machine, in particular to a peritoneal dialysis machine, having a device for preparing dialysis solution, wherein the device has an RO system equipped with a filter for the provision of RO water and has a mixing device that is configured to mix a dialysis concentrate with the RO water or with a solution containing RO water; wherein a control device is provided that is configured to operate the RO system continuously; and wherein a storage container is provided that is connected downstream of the RO system and that is configured to store the water generated in the RO system.

A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder.

A method of performing a peritoneal dialysis treatment includes connecting a disposable unit to a source of water. The disposable unit includes at least a first container holding a sterile concentrate containing an osmotic agent, a second container holding a sterile concentrate containing electrolytes, an empty sterile mixing container, and a tubing set with a pre-attached peritoneal fill/drain line. The method also includes receiving a prescription command by a controller, indicating at least the fill volume and desired final concentration of the osmotic agent to be used for a current fill cycle under said treatment, and pumping a quantity of the concentrated osmotic agent that is at least sufficient to achieve the desired final concentration into the mixing container. The contest of the mixing container are mixed, further diluted or concentrated, and then flowed to a patient.

A method of performing a dialysis treatment includes using a pump and a dialysate supply line to transport peritoneal dialysis fluid, the supply line having a proximal end into which peritoneal dialysis fluid is supplied and from which spend dialysate is withdrawn, and a distal end which is connected to a patient's peritoneal access. The method further includes generating proximal and distal pressure signals using pressure detectors located at both the proximal and distal ends, respectively, of said supply line. During a drain cycle in which spent dialysate is pumped from the patient, the method includes, responsively to the proximal and distal pressure signals, detecting a characteristic of a pressure difference between the distal and proximal ends whose magnitude is determined by a predicted change in dialysate properties, and responsively to the characteristic, generating a signal indicating the change in dialysate properties.

Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

A method of performing a peritoneal dialysis treatment includes connecting a disposable unit to a source of water, the disposable unit including at least a first container holding a sterile concentrate containing an osmotic agent, a second container holding a sterile concentrate containing electrolytes, an empty sterile mixing container, and a tubing set with a pre-attached peritoneal fill/drain line. The method further includes receiving a prescription command by a controller, indicating at least the fill volume and desired final concentration of the osmotic agent to be used for a current fill cycle under said treatment, and using the controller, pumping a quantity of the concentrated osmotic agent that is at least sufficient to achieve the desired final concentration into the mixing container. The contents of the mixing container are mixed, further diluted or concentrated, and then flowed to a patient.

A disposable fluid circuit used in a medical device that performs peritoneal dialysis includes a peritoneal dialysis tubing set that has a connection tube with a connector for a peritoneal catheter at a distal end and a connector configured to connect to a peritoneal cycler at a proximal end. The circuit also includes a pressure pod at the distal end, the pressure pod being of the type that has a flow chamber for carrying a liquid and an air chamber separated from the flow chamber by a diaphragm and an air port in fluid communication with the air chamber. The flow chamber is connected in-line with a lumen of the connection tube and a length of tubing runs from the air-port along the length of the connection tube with a connector at the proximal end configured to connect to a pressure transducer.

The invention relates to an apparatus for preparing ready-to-use solutions for peritoneal dialysis that has a sterilization compartment; a filling line leading to the sterilization compartment and having a connector arranged at its end at the compartment side for connecting a disposable; a water treatment system arranged in the filling line; and a sealing system. The invention further relates to a disposable for preparing ready-to-use solutions for peritoneal dialysis in such an apparatus and to a method of preparing ready-to-use solutions for peritoneal dialysis using such an apparatus and such a disposable.

A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.

The invention relates to an apparatus for preparing ready-to-use solutions for peritoneal dialysis that has a sterilization compartment; a filling line leading to the sterilization compartment and having a connector arranged at its end at the compartment side for connecting a disposable; a water treatment system arranged in the filling line; and a sealing system. The invention further relates to a disposable for preparing ready-to-use solutions for peritoneal dialysis in such an apparatus and to a method of preparing ready-to-use solutions for peritoneal dialysis using such an apparatus and such a disposable.