A device and a method for the metered dispensing of a liquid for the purpose of releasing an active substance in a human or animal body, and to a use of a device. A device for the metered delivery of a liquid for the purpose of releasing an active substance in a human or animal body comprises a metering apparatus for metering a defined volume of a liquid, an inlet in fluidic communication with the metering apparatus for supplying liquid into the metering apparatus and an outlet in fluidic communication with the metering apparatus for dispensing the defined volume of the liquid. The metering apparatus comprises a wall which encloses a metering cavity for receiving the liquid. By means of manual pressure on the wall, the metering cavity may be reduced, so that the defined volume of the liquid is delivered from the metering cavity to the outlet.

Infusion devices and methods are provided for a drug delivery system and can include an infusion needle (1) having a tip end (2) and a drive unit (D) coupled to the infusion needle and arranged for advancing the tip end of the infusion needle to penetrate any fibrosis when the infusion device is implanted in a patient's body. The infusion needle and drive unit are designed for implantation in a patient's body. Other components of the drug delivery system may be part of the implantable infusion device or, alternatively, be for extracorporal use cooperating with the implanted infusion device. Preferably, the infusion needle can be advanced and retracted with each infusion cycle. Furthermore, upon each advancement and/or retraction, the needle may be moved laterally so as to vary the injection site. Needle (1) and drive unit (D) are preferably disposed within a body (15), with the infusion needle being arranged for penetrating a self-sealing penetration membrane (18).

An at least partly implantable system for injecting a substance into a patient's body. The system comprises at least one flexibly bendable infusion needle with a tip end of each of said at least one infusion needle arranged in at least one first housing for penetrating the first housing's outer wall in at least one penetration area and having the respective other end arranged in at least one second housing, the first and second housings being adapted for implantation inside the patient's body, wherein the at least one second housing is provided for implantation inside the patient's body remote from the at least one first housing and wherein the injection needle is sufficiently long to bridge the distance from the at least one second housing for remote implantation to the at least one first housing and further through the first housing up to the outer wall of the first housing. The system further comprises at least one drive unit adapted for being coupled to the at least one infusion needle and arranged at least for advancing the tip end of the at least one infusion needle so that the at least one infusion needle penetrates with the tip end or ends thereof said at least one first housing's outer wall in said at least one penetration area.

A catheter system may include a catheter assembly, a fluid storage unit, and fluid. The catheter assembly may include a catheter hub, a catheter, an extension tube, and an adapter. The catheter hub may include a distal end, a proximal end, a lumen extending between the distal end and the proximal end, and a side port. The catheter may extend distally from the distal end of the catheter hub. A distal end of the extension tube may be coupled to the side port. The adapter may be coupled to a proximal end of the extension tube. The fluid storage unit may be coupled to the adapter and may include a reservoir, a barrier, and an actuator. The fluid may be disposed within the reservoir. In response to breach of the barrier by the actuator, the reservoir may be in fluid communication with the lumen of the catheter hub.

A catheter system may include a catheter assembly, a fluid storage unit, and fluid. The catheter assembly may include a catheter hub, a catheter, an extension tube, and an adapter. The catheter hub may include a distal end, a proximal end, a lumen extending between the distal end and the proximal end, and a side port. The catheter may extend distally from the distal end of the catheter hub. A distal end of the extension tube may be coupled to the side port. The adapter may be coupled to a proximal end of the extension tube. The fluid storage unit may be coupled to the adapter and may include a reservoir, a barrier, and an actuator. The fluid may be disposed within the reservoir. In response to breach of the barrier by the actuator, the reservoir may be in fluid communication with the lumen of the catheter hub.

The present invention relates to an at least partly implantable system for injecting a substance into a patient's body. The system is provided with at least one infusion needle disposed at least partly within at least one housing with a tip end of the at least one infusion needle arranged for penetrating the at least one housing's outer wall, and at least one drive unit adapted for implantation inside the patient's body, the at least one drive unit being coupled to the at least one infusion needle and arranged for advancing and retracting the tip end of the at least one infusion needle so that the at least one infusion needle penetrates, upon advancement of the tip end thereof, said at least one housing's outer wall in at least one penetration area so as to allow for injecting the substance through said at least one penetration area via the at least one infusion needle.

A method of determining a presence of suction in a patient having an implantable blood pump from down-sampled log files. The method comprising calculating a waveform index for each of a plurality of flow rate data points from the down-sampled log files. The calculated waveform index is compared with a predetermined waveform index threshold. A non-suction trough baseline is calculated from the plurality of flow rate data points. A difference between a measured trough and a calculated non-suction trough baseline is compared with a predetermined threshold. The presence of suction for each of the plurality of flow rate data points is determined if the calculated waveform index is greater than the predetermined waveform index threshold and the difference between the measured trough and a calculated non-suction trough baseline is greater than the predetermined threshold.

A medical device and system for the administration of a medical substance or for dosing body fluids comprising a rotor, rotating around an axis X-X, operatively connected to an injection device of said medical substance, and a rotor locking/unlocking device mechanically separate from the rotor and integral in rotation therewith. The locking/unlocking device comprises, in one piece, a disc, centered with respect to said axis X-X, from which a plurality of flexible fins radially unravel. The flexible fins are configured to flex around transverse hinges at a connection portion with the disc, and are angularly spaced so as to define gaps between adjacent pairs of fins which prevent interferences between adjacent fins in the respective flexing movement. The flexible fins are associated with ferromagnetic means for the operation of the same fins and locking/unlocking means of the rotation of the disc. The disc and fins are formed from a single plastic body.

The present invention relates to a method of replenishing a system for injecting a substance into the patient's body, when the system is implanted in the patient's body. The method involves replenishing the implanted reservoir by a replenishing needle penetrating the patient's skin and injecting infusion liquid comprising the substance through the replenishing needle directly or indirectly into the reservoir.

The device presented is designed to cause, in a mode of operation referred to as “normal” mode, a fluid to flow along this fluid path successively through the first cavity, the filter, the second cavity then the flow restrictor. The device is also designed to cause, in a mode of operation referred to as “purge” mode, a fluid to flow along this same fluid path through the filter but in the opposite direction to the normal flow of the fluid (in the normal mode of operation). Thanks to the “purge” mode, the fluid will detach impurities that have become trapped on the filter in order to clean same.