A system and method for delivering a therapeutic agent such as filler materials, biocompatible gels, and other substances through a catheter. The therapeutic agent can be a single component or multiple components that are delivered separately or mixed just prior to delivery or at the delivery site. The system and method use an automated delivery mechanism to maximize delivery of the therapeutic agent to the target tissue and minimize loss of the therapeutic agent within the catheter. The system and method are particularly useful for interventional approaches that deliver therapeutic agents to the wall of the heart.

Method and system for controllably administering and/or withdrawing fluid from a patient. In one embodiment, the system may include an infusion needle, a pump adapted to be operably coupled to the infusion needle for creating fluid flow through the infusion needle, and a hands-free switch for activating and/or deactivating the pump.

A patch pump includes a needle assembly, a reservoir, a preparation, and an inflatable component. The needle assembly includes a cannula, and a plunger slidably disposed in the cannula. The plunger has a pointed tip and is structured to move within the cannula upon application of a force on the plunger such that the pointed tip of the plunger extends from the cannula to form a channel in a tissue of a subject. The reservoir is fluidically coupled to the needle assembly, and the preparation is contained in the reservoir. The inflatable component is structured to, upon inflation, press against the reservoir to force the preparation from the reservoir and into a flowpath between the reservoir and the cannula.

An electrochemical pump adopts a hybrid pulse to intermittently activate an electrochemical reaction. The abovementioned electrochemical pump can save power effectively to prolong the lifetime of the electrochemical pump. In addition, an electrochemical pump increases the bonding strength between electrodes and a substrate by covering edges of the electrodes with an insulating layer to avoid electrode delamination caused by high-power electrochemical reactions. A delivery device using the abovementioned electrochemical pump is also disclosed.

An injection device (1) for injecting a medical liquid, comprising: —a piston (6) arranged within an inner space (4) delimiting an upper space (4b) and a lower space (4a), —an evacuation path, said evacuation path traversing the piston (6) the lower space (4a) to the upper space (4b) of the inner space, —a selector (24) between a lower portion (17a) and an intermediate portion (17b) of the evacuation path, configured for selectively allowing the gas to go through and preventing the medical liquid from going through said selector (24, 50, 60), —a purge valve (22) between between a blocking and a passing configuration which requires an overpressure in the intermediate portion (17b) caused by the piston (6) travelling towards the lower end of the body (2).

Provided is an epidural device configured to inhibit or substantially or completely prevent further progression of an epidural needle upon entry of the needle into the epidural space. When the needle is inserted into the ligamentum of the patient's back, the device may be pressurized with fluid using the resistance of the dense ligament to maintain pressure. This pressurization may lock a pushing mechanism in place relative to the needle such that the pushing mechanism can be used to advance the needle. Once the epidural space is reached, the fluid (e.g., saline or air) enters the epidural space, and the release of pressure may cause the trigger mechanism to disengage from the sliding pusher, allowing the pusher to slide along the body of the construct. The device thus may provide the ability to detect the epidural space using pressure loss while preventing the needle from advancing into the dura once the space is reached. In a preferred aspect, the device may prevent premature triggering when there is a slow flow of fluid from the epidural needle into the surrounding tissue.

Systems and methods for delivering a medication to a person experiencing an emergency medical event without requiring intervention or action on the part of the person. A device encases a reservoir of medication and a delivery mechanism. Sensors in the housing sense a physical attribute of the person and circuitry monitors information collected by the sensors to determine if the person is experiencing a severe medical condition or event based on the information. An input device on or in the housing, such as a button, may be used or activated by the person if the detected condition or event is a false positive to cancel further action. If the system does not include the button or if the user does not press it in time, the system activates the delivery device and injects the medication into the person.

A drug delivery device includes a container for storing a drug, the container having a stopper for expelling the drug; an injection drive comprising an energy source for directly or indirectly acting on the stopper to expel the drug; a sensor for detecting contact between the drug delivery device and a body of a patient; and a user interface (UI) for activating or causing the activation of the injection drive. The device is operative for drawing attention to the UI, if the sensor detects contact between the drug delivery device and the body of the patient, to thereby indicate that the injection drive is ready to be activated, which activation is the next step in the drug administration process.

A drug delivery device includes a housing releasably coupled with a patient, a pressure chamber disposed in the housing and including a vent, a container at least partially disposed in the pressure chamber for storing a drug connectable in fluid communication with a fluid conduit, an activation mechanism, and a relief mechanism. The activation mechanism releases a pressurized drive fluid into the pressure chamber for expelling the drug from the container into the fluid conduit. The relief mechanism is operably coupled to the fluid conduit and is adapted to open the vent to release the drive fluid from the pressure chamber in response to a predetermined condition.

A micro-delivery device includes a substrate having an upper surface; a shell disposed on the upper surface of the substrate and defining a chamber between the shell and the substrate; a planar electrode disposed on the upper surface of the substrate; a separator disposed in the chamber and dividing the chamber into an upper reservoir and a lower reservoir; and a cannula inserted in an opening of the rigid shell and in fluid communication with the upper reservoir.