Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.

Disclosed is a syringe for a micro-dosing syringe pump. The syringe includes a reservoir having an outlet port; a plunger having a track, with the plunger received inside a portion of the reservoir; a plunger driver comprising a gear connected to one end of a shaft and a pin located adjacent an opposite end of the shaft, with the plunger driver received inside the plunger and with the pin located inside and engaging the track. In use, rotation of the gear in a first direction advances the plunger into the reservoir a first distance as the pin travels in the track and rotation of the gear in a second direction opposite the first direction advances the plunger a further distance into the reservoir as the pin travels in the track. The design prevents excess dosing in a runaway motor failure.

A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system.

A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system.

Various fluid delivery systems are described comprising an infusion pump having a housing with a first opening and a hollow interior portion that is configured to receive a cartridge having a tubing. A pump unit can be disposed within the housing. The pump unit comprises a motor mechanically coupled with a crank shaft or eccentric cam that is configured to move a set of pistons or other objects to thereby compress one or more portions of the tubing over time as the crank shaft or eccentric cam rotates.

There is described a patch pump comprising a cartridge, a power source, a pump system, a drug delivery device and a control system configured to operate in particular the pump system and the drug delivery device. The pump system includes, on the one hand, a pump having a pump housing containing a pump piston and a valve piston and, on the other hand, a pump drive including a piston motor and a valve motor for driving the pump piston and the valve piston independently from each other through a first and a second transmission. The drug delivery device includes a transdermal delivery system having a needle actuation mechanism configured for transdermal insertion of a cannula.

A miniature patch-type control infusion device includes an infusion unit (102). The infusion unit (102) comprises a drug storage unit(s) (100), a metal piece (110), a piston(s) (120), a rigid screw(s) (130), a rotating shaft (160), a driving unit(s) (150), a driving wheel(s) (140) provided with wheel teeth (141), a power unit(s) (180) and a rebound unit(s) (170). The driving unit (150) includes at least two driving portions (151a, 151b). The driving unit (150) can rotate around the rotating shaft (160) in the driving direction and the returning direction. The power unit (180) and the rebound unit (170) cooperate with each other to apply force to the driving unit (150) to rotate the driving unit (150). The infusion device also includes a position detector(s) (190), the metal piece (110) and the position detector(s) (190) interact to generate signals. Using this infusion device, patients will have more infusion rate options, which increase the flexibility of controlling drug infusion.

A unilaterally driven drug infusion device includes: a reservoir, a piston and a screw, the piston connected with the screw and arranged in the reservoir; a driving unit including rotating shaft and driving member, and the driving member including driving end; driving wheel provided with wheel teeth; a linear actuator and a reset unit respectively connected to the driving member; and at least two blocking walls, arranged at one side of the driving unit to limit the advancing position of the driving unit. The infusion device is able to precisely control the rotation amplitude of the driving member and improve the infusion accuracy of the infusion device. The user or the closed-loop system is able to flexibly select different infusion modes to precisely control the body fluid level to meet the needs of the body, improving user experience.

A peristaltic infusion pump with improved low flow performance. The pump includes a cam shaft having cams offset in an axial direction, pump fingers that engage a tube, each finger coupled to a respective cam, the fingers creating a pumping region and an occlusion region within the tube, a motor coupled to the cam shaft, a memory, and a controller. The controller implements cam rotation instructions received from the memory to cause the pump to position the fingers in the occlusion region prior to beginning an infusion therapy to deliver fluid to patient through the tube at a patient fluid delivery rate, rotate the cam shaft to transition the fingers from the occlusion region to the pumping region at a startup rate that is faster than a patient fluid delivery rate, and rotate the cam shaft at the patient fluid delivery rate in the pumping region.