A system for delivering a medicinal fluid to a patient includes a variable volume pressure delivery chamber, a variable volume medication chamber, an optional medication reservoir, a movable delivery element, a fixed reference volume chamber, a pressure source, and a control sub-system. The variable volume pressure delivery chamber is configured to store pressure controllably. The variable volume medication chamber is fluidically isolated from the pressure delivery chamber and is configured to store medicinal fluid. The movable delivery element is disposed between the medication chamber and the pressure delivery chamber. The pressure source is coupled to the pressure delivery chamber. The control system is configured to selectively cause the pressure source to deliver pressure to the pressure delivery chamber causing the movable delivery element to apply pressure to the medicinal fluid in the medication chamber thereby causing the medicinal fluid to exit the medication chamber at an outlet along the fluid communication path to the patient.

Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an interior surface defining an enclosed space, and an exterior surface releasably attachable to a patient. A container may be disposed in the enclosed space and include a reservoir containing a drug and a stopper. A drive assembly may also be disposed in the enclosed space and configured to move the stopper through the reservoir to expel the drug from the reservoir. The drive assembly may include a rotational power source and a gear module. The gear module may include a mounting plate and a plurality of gears rotatably connected to the mounting plate. Furthermore, the mounting plate may be separate from the main housing.

A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of the user. The housing comprises a communication device configured to wirelessly communicate a physiological characteristic to a communication component of a fluid infusion device. The fluid infusion system includes a fluid flow path from the fluid infusion device into the anatomy of the user, and the fluid flow path is configured to extend from the housing for insertion into the anatomy of the user.

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

A method, computer program product, and infusion pump assembly for determining a first rate-of-change force reading that corresponds to the delivery of a first dose of an infusible fluid via an infusion pump assembly. At least a second rate-of-change force reading is determined that corresponds to the delivery of at least a second dose of the infusible fluid via the infusion pump assembly. An average rate-of-change force reading is determined based, at least in part upon the first rate-of-change force reading and the at least a second rate-of-change force reading.

A fluid delivery system includes a control interface and multiple unique loading guides. The control interface of the fluid delivery system receives a fluid pump assembly. The multiple loading guides are retractable from the fluid delivery system to retain and control movement of a facing of the fluid pump assembly to contact the control interface on the facing of the fluid delivery system. In one configuration, the control interface is disposed in a cavity of the fluid delivery system; the multiple loading guides are disposed at locations in proximity to the cavity. The multiple loading guides slidably retract in unison to support substantially orthogonal insertion of the fluid pump assembly into the cavity of the fluid delivery system.

A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

A removable power supply cover assembly (116) for an infusion pump is disclosed. The assembly includes a housing body configured to removably attach to an infusion pump, a conductor assembly (1020) attached to the housing body, a power supply contact assembly, and a spring (1002) attached to the power supply contact assembly and the conductor assembly. An electrical coupling between a power supply to the conductor assembly is formed through the spring.

The present invention relates to a medical apparatus, methods and system for fluid medication delivery. The apparatus has a drive mechanism module and a fluid container engaged to the drive mechanism. The drive mechanism includes a resilient member compressed to act against a gasket movably disposed in the fluid container. When extending to its original shape, the resilient member pushes the gasket to move inside the fluid container to eject the fluid out of the fluid container. The fluid container is connected to a flow restrictor tube that allows a predetermined flow rate of medication to be infused or injected to a patient.

A connecting arrangement for connecting a syringe to an electromechanical pump for drug infusion is provided. The syringe comprises a hollow cylindrical syringe body having a first, tapered open end for discharging the drug and a second open end. The syringe body is surrounded by connecting means arranged to firmly connect the syringe to the pump in a removable manner, an axially sliding plunger being housed in the syringe body for causing suction and injection of the drug through the first end. The pump comprises a pump body housing electromechanical members comprising a sliding rod partially projecting out of the pump body to cause sliding of the plunger within the syringe body of the syringe connected to the pump. The pump body being provided with connecting means arranged to receive in an engaging configuration the syringe body. The connecting means provided on the pump body comprise a cylindrical collar axially extending around the sliding rod and being internally provided with engaging elements, the collar defining a sealing end. The connecting means surrounding the syringe body comprise engaging elements arranged to cooperate with the engaging elements provided in the collar for firmly connecting the syringe to the pump in a removable manner. An annular flange extends radially around the syringe body. The flange cooperates with the sealing end defined in the collar to establish a tight sealing between the syringe body and the collar, whereby, when the syringe is attached to the pump, any moisture that may be present in the surrounding environment outside the pump and the syringe attached thereto does not penetrate into the pump body.