An injection system has: a gasket having a plurality of engaging claws, wherein each of the engaging claws includes an inner surface S1 which defines a hole H having an inlet with an enlarged diameter and an outer surface S2 inclined in a direction away from a perpendicular line P passing through a center of the hole H, and the engaging claws are to be displaced between a widened position and a narrowed position; a rain to be inserted into the hole H so as to engage with the engaging claws; a cylinder, into which the gasket is to be inserted, contacting the outer surfaces S2; and an injection device configured to move the ram forward and injecting a chemical solution in the cylinder. An annular groove which serves as a starting point of deformation of the engaging claws is formed on the gasket.

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Multi-medicament infusion systems prevent cross-channeling of medicaments. A system may include one or more of an infusion pump, medicament reservoirs, a multi-channel fluid conduit, and an infusion set. Medicament reservoirs and/or collars may be sized and shaped differently such that the medicament reservoirs can only be inserted into the system under selected configurations.

A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engageable with the piston regardless of a rotational orientation of the piston relative to the plunger.

A syringe retaining element protruding radially outward relative to an outer surface of a sidewall of a barrel of a syringe is described. The syringe retaining element is configured for interacting with a locking mechanism of a syringe port of a fluid injector to releasably retain the ring. Features of the syringe retaining element allow the syringe to be axially ejected from the syringe port upon rotation of the syringe. Other features of the syringe retaining element allow the syringe to engage the locking mechanism of the syringe port and rotationally guide the syringe into self-orienting alignment with the locking mechanism.

A panel fastener is provided that has a head having a first surface and a second surface opposite the first surface; an engagement feature on the first surface of the head, the engagement feature being configured to be engaged by a driving tool; a shank extending from the second surface of the head; a threaded portion extending from the shank, the threaded portion having first and second helical threads arranged in an intertwined manner; the first thread extending farther radially from the central axis than does the second thread; and the shank being located between the head and the threaded portion.

A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe from the port upon rotational disengagement of the syringe from the port.

A system for inserting a pharmaceutical cartridge into a delivery device is described. The cartridge can be inserted in an arbitrary orientation and the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. The torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. When the cartridge reaches the locked orientation, an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Once the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.

A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

The present invention relates to a plunger capable of moving back and forth and a medicine injection device including same, in which, by manually or automatically moving the plunger backwards, user convenience may be provided. In addition, according to the present invention, when a rotation unit (20) is no longer rotated, first flat portions (151-1, 151-2) of a first adjusting portion (150-1) and a second adjusting portion (150-2) are slid in an inclined direction, that is, in a direction from a second housing (120) to the rotation unit (20), respectively along a first inclined portion (121) and a second inclined portion (122), so that the first adjusting portion (150-1) and the second adjusting portion (150-2) are spaced apart from each other, and thus a pushrod unit (10) can be moved in a direction of the rotation unit (20), that is, backwards.