An infusion pump (100) includes a plunger (110) configured to squeeze a section of an infusion tube (150). A proximal valve (120), proximal to the plunger, ascends to allow infusion fluid intake from a reservoir to the infusion tube and descends to inhibit infusion fluid intake from the reservoir to the infusion tube. A distal valve (125), distal to the plunger, ascends to allow infusion fluid flow past the distal valve, and descends to inhibit infusion fluid flow past the distal valve. A controller (141) controls the plunger, proximal valve, and distal valve by initiating descending of the plunger concurrently with or prior to the ascending of the distal valve, such that the descending of the plunger compensates for suction produced by the ascending of the distal valve, thereby reducing backflow of fluid from the subject. Other applications are also described.

Certain embodiments are directed to an inline device(s) for monitoring a fluid path.

The invention is a process and system, consisting of a reinjection pump, connecting tubing, a reinjection cannula and a recipient site, with fluid management features including a peristaltic pump head and controls for pressure limits, flow rates and flow distribution wherein the process of controlling the reinjected fat and fluid is unique because of the control of flow rates, pressures, matching cannula hole sizes, and maintaining a closed continuous system where the harvesting and reinjection is done all together with a completely closed system. The process utilizes a method and control system to manage pressure levels during reinjection procedures of viable soft tissue. Although this case specifically relates to its use in the reinjection of adipose fat and other tissue back into the body during liposuction procedures, it can be applied to any medical procedure of introducing or re-introducing materials into the body.

Disclosed is an infusion pump which may include a native pumping mechanism to drive fluids through a functionally associated conduit, at least one native sensor to sense a physical characteristic of the fluid within the conduit and computing circuitry having a decalibration test mode to determine whether the infusion pump is decalibrated. The computing circuitry may be adapted to receive output from at least one native sensor during the decalibration test mode.

An infusion pump includes upstream and downstream valves, a pressing surface disposed between the valves which presses on an infusion tube, a pressure sensor which measures pressure within the infusion tube, and a controller. In response to the pressure, the controller determines that there is an occlusion in the infusion tube downstream of the downstream valve, and in response thereto, toggles the upstream valve and the downstream valve. The toggling includes sequentially, (a) while the upstream valve remains closed, isolating a segment of the infusion tube between the valves by closing the downstream valve, (b) while the downstream valve remains closed, reducing pressure in the isolated segment by opening the upstream valve, (c) while the downstream valve remains closed, closing the upstream valve, and (d) while the upstream valve remains closed, reducing pressure downstream of the downstream valve by opening the downstream valve. Other applications are also described.

An infusion pump includes inlet and outlet valves and a squeezing element configured to squeeze a fluid line coupled to the infusion pump. A method includes at least one round of valve operation check prior to initiation of a delivery session of fluid to a subject, and subsequently, after an intake phase and before a delivery phase of at least one infusion pump cycle, determining for the at least one pump cycle, an absolute amount of air in the fluid line. The valve operation check and the determining of the amount of air each include: (A) closing the inlet valve to confine a section of the fluid line between the inlet and outlet valves; (B) squeezing the confined section; (C) measuring the pressure within the confined section; and (D) subsequently, relieving the pressure in the confined section. Other applications are also described.

A method of pressure management for a drug delivery device including a pump, a fluid line, and a power source, includes: delivering fluid through the fluid line via the pump; determining a parameter indicative of pressure within the fluid line; determining whether the parameter indicative of pressure within the fluid line exceeds a pressure threshold level; pausing the delivery of fluid through the fluid line until a predetermined condition is satisfied; and resuming the delivery of the fluid through the fluid line after the predetermined condition is satisfied.

A drug delivery device includes a power source, a reservoir configured to receive a fluid, a fluid line in fluid communication with the reservoir, a pump configured to deliver a fluid from the reservoir to the fluid line, and a power limitation subsystem configured to limit a power level supplied to the pump.

An implantable pump configured to enable tuning of a delivery velocity of a fixed quantity of medicament. The implantable pump including a pump, an accumulator and a valve configured to enable tuning of a delivery velocity of a fixed quantity of medicament, wherein operating the pump with the valve continuously in the open state enables a steady-state delivery of medicament at a first velocity, and wherein closing of the valve enables the pump to at least partially fill the accumulator and subsequent opening of the valve enables the at least partially filled accumulator to dispense medicament, thereby delivering a bolus of medicament at a second velocity, wherein the second velocity is greater than the first velocity.

An infusion pump includes a housing with a door pivotally mounted to the housing, a tube channel on the housing configured to hold a tube in the infusion pump, a pumping mechanism including a shuttle, and a slide clamp ejection device.