A pump for pumping fluid includes a tube platen, a plunger, a bias member, inlet and outlet valves, an actuator mechanism, a position sensor, and a processor. The plunger is configured for actuation toward and away from the infusion-tube when the tube platen is disposed opposite to the plunger. The tube platen can hold an intravenous infusion tube. The bias member is configured to urge the plunger toward the tube platen.

A fluid container is encompassed by a custom fluid container pressure sleeve, which is configured to wrap around, connect and form to the malleable fluid container such that, when the fluid container pressure sleeve is inflated with a gas, the fluid container pressure sleeve applies an inward directional pressure to the malleable fluid container from an exterior of the malleable fluid container to compress the malleable fluid container. A pump connected to the fluid container pressure sleeve is activated to provide the gas to the fluid container pressure sleeve to compress the malleable fluid container and direct a fluid (e.g., the blood product) within the malleable fluid container toward and through a connected infusion tubing

A method for detecting an occlusion in a fluidic channel of an infusion device that includes flowing a fluid within the fluidic channel during a first period of time in which a flow rate of the fluid is set to a first flow rate; pausing, the flow rate for a second period of time; measuring, a first pressure at a location along the fluidic channel during the second period of time; increasing, after measuring the first pressure, the flow rate to a second flow rate; pausing, the flow rate for a fourth period of time; measuring, after pausing the flow rate, a second pressure at the location during the fourth period of time; computing, at a processor, a difference between the first and second pressures; and in accordance with a determination that the magnitude of the difference satisfies the threshold, providing an indication, of a presence of the occlusion.

An apparatus and method to enable clinicians to verify needle or catheter location within an anatomic site by relying upon combined sensing of two signals, such as a pressure signal and a heart rate pulse signal, in which the detection of a correlation between both signals is identified to confirm location of the needle or catheter.

The present disclosure provides systems that include a flow probe that senses fluid flow or mass flow of fluid delivery to a patient. Based at least in part on the sensed fluid or mass flow, the flow probe provides flow-related data (e.g., volume or mass flow rate) that the system uses to derive a volume of fluid being delivered. The fluid can be delivered from an IV bag, another in-line port, or a combination of the two. The disclosed systems provide fluid volume and/or fluid rate for display to a clinician and an informative understanding of what volume of fluid/mass a patient has received.

A method for measuring a size of a fluid-filled conduit in a fluid-delivery device includes (A) isolating a segment of the fluid-filled conduit by occluding a first site of the fluid-filled conduit and a second site of the fluid-filled conduit (B) iteratively increasing pressure within the isolated segment, by incrementally squeezing a portion of the isolated segment of the fluid-filled conduit, (C) for each iteration of squeezing, measuring an increase in force exerted by the isolated segment of the fluid-filled conduit, associated with a respective pressure change during that incremental squeezing, and (D) measuring an indication of the size of the conduit when an increase in force exerted by the isolated segment, measured in response to an incremental squeezing of the portion of the isolated segment of the fluid-filled conduit, passes above a threshold value. Other applications are also described.

A system and method for monitoring a fluid delivery is disclosed. The system includes a processor and one or more sensors configured to measure one or more fluid state parameters associated with a fluid delivery channel through which a fluid is delivered to an infusion site of a patient. The processor receives fluid information for the fluid and at least one measured fluid state parameter from the sensor, determines at least one expected fluid state parameter for the infusion site based on the fluid information and patient information associated with the patient, and provides a communication at an output device when the at least one measured fluid state parameter deviates from the at least one expected fluid state parameter by more than a threshold deviation.

A pump for pumping fluid includes a tube platen, a plunger, a bias member, inlet and outlet valves, an actuator mechanism, a position sensor, and a processor. The plunger is configured for actuation toward and away from the infusion-tube when the tube platen is disposed opposite to the plunger. The tube platen can hold an intravenous infusion tube. The bias member is configured to urge the plunger toward the tube platen.

The invention comprises a cardiovascular state monitoring apparatus and a method for operating a drug delivery system, comprising the steps of: (1) receiving to the cardiovascular state monitoring/drug delivery system a first time-varying cardiovascular input waveform from at least one of: a pulse oximeter and a blood pressure monitor; (2) operating on the time-varying cardiovascular input waveform to generate transient cardiovascular state information, comprising at least one of: a current left ventricle stroke volume, a current blood pressure, a current arterial compliance, and a current blood flow rate; and (3) directing the drug delivery system to deliver a drug based on the generated transient cardiovascular state information.

A system may include an intravenous (IV) catheter comprising a first portion configured to be inserted into a vein of a patient and a second portion configured to remain outside a patient when the first portion is inserted into the patient. The IV catheter may include a pressure sensor configured to detect a pressure of a fluid associated with the IV catheter. A method may include receiving data associated with the pressure of the fluid associated with the IV catheter, and determining whether the IV catheter is inserted into the vein of the patient based on the pressure of the fluid associated with the IV catheter.