A therapeutic product delivery device is described which comprises a device body and a cartridge for holding a therapeutic product. An engagement structure is provided for releasably engaging the cartridge with the device body. A fault detector is provided for detecting a fault in the delivery of the therapeutic product from the cartridge. A release trigger is responsive to the detection of a fault to cause the engagement structure to release the cartridge from the device body. In this way, a fault causes the cartridge to be released from the device body, which will prevent any further delivery of the therapeutic product to the patient. This solution is strongly preferable to a solution in which a product delivery mechanism (e.g. a pump) is merely paused or stopped, since when the cartridge separates then no further delivery is possible at all, until the cartridge is reattached (or more probably replaced with a new cartridge in case the fault is with the cartridge).

Device for dispensing a substance having: a dispensing element through which the substance can be dispensed, a displaceable protective element for the dispensing element, a drive element that is coupled with the protective element and a feedback element which can generate a signal when or after a predefined quantity or the entire quantity of the substance to be dispensed has been dispensed characterized in that the feedback device is coupled with the drive element.

The present disclosure relates to a cartridge assembly provided with a fixing member, wherein the fixing member is configured for fastening to a cartridge, wherein the cartridge is configured for insertion into a housing component of a drug delivery device, wherein the housing component comprises a sidewall confining a cartridge receiving space, the cartridge receiving space extending in a longitudinal direction (z), the fixing member comprising: a fastening portion for fastening to a neck portion of the cartridge, a fixing structure comprising a first fixing element configured to engage with a counter fixing structure of the housing component, and an alignment portion configured to align with a counter alignment structure provided on or in the sidewall of the cartridge holder.

An automatic injector for delivering a pharmaceutical substance from a reservoir of a cartridge, the cartridge interconnected to a needle at its distal end and mechanically coupled to a plunger driver at its proximal end, the injector comprising a connecting feature on the cartridge a contact surface for contacting an injection site a frame connected to the contact surface, the frame having an interference element with a distal stop, the interference element sized to slidably link to the connecting feature and allow the cartridge to slide up to the distal stop, a snap element allowing the interference element to receive the connection feature, but inhibiting disconnection of the cartridge; the frame further comprising a driver mount, for fixedly containing a plunger driver, the driver for driving a plunger to empty the reservoir of the cartridge through the needle to inject fluid from the reservoir into the injection subject.

Container holder assembly for use in a medicament delivery device, comprising a tubular body elongated in an axial direction, said tubular body having a proximal end and an opposite distal end, and a retaining member releasably arranged to said tubular body for securing an elongated container placed inside the tubular body, wherein said retaining member comprises a resilient structure capable of exerting an axial force on said container in said tubular body for holding the container in a fixed position inside the tubular body and thereby avoiding displacement or breakage of the container and wherein a distal end of said container protrudes from a distal end of said tubular body.

The present invention relates to an autoinjector device (10) for use in combination with a syringe (30), said syringe 0 comprising a movable plunger; a needle; and a tubular needle shield (34). The claimed autoinjector device (10) comprises: an elongated housing having a proximal (11) and a distal end (12); a drive mechanism; a syringe holder (40) in order to support the fragile Csyringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

A cassette for a drug delivery device is described that includes a sleeve, a syringe having a barrel disposed in the sleeve, and a plunger-stopper slidably disposed within the barrel. The cassette further includes a spacer that is configured to be coupled to the sleeve. The cassette can form a part of an apparatus for injection of a therapeutic product along with a drug delivery device.

Syringe carriers for medicament delivery devices are described where a medicament delivery device sub-assembly extending along a longitudinal axis from a proximal end to a distal end is described having a tubular housing, a tubular syringe carrier inside the housing and a syringe inside the syringe carrier. The syringe includes a needle shield and a medicament container comprising a shoulder. The housing includes a flexible arm extending in the axial direction relative to the longitudinal axis, the flexible arm having an inwardly extending protrusion arranged in a gap between the shoulder and the needle shield. The syringe carrier has a proximal portion and a distal portion, and the proximal portion is arranged adjacent to the flexible arm of the housing so that movement of the flexible arm of the housing in a radial direction relative to the longitudinal axis is restricted by the proximal portion of the syringe carrier.

A dispensing device and cartridge for simultaneous delivery and mixing of multiple co-reactive materials, the cartridge having proximal and distal ends, and having an elongated holder body with substantially parallel longitudinal voids. Multiple syringe bodies are disposed parallel within the voids and multiple co-reactive materials are separately disposed in the syringe bodies. The dispensing device also includes a longitudinal housing which is structured and arranged to receive the cartridge.