A gas sterilizable syringe includes an enclosure having walls that define a fluid chamber. A flowable material is disposed within the fluid chamber of the enclosure. A plunger is assembled with the enclosure and is moveable toward a distal end of the enclosure for dispensing the flowable material. One or more apertures are formed in at least one of the walls of the enclosure. A gas permeable barrier covers at least one of the apertures formed in at least one of the walls of the enclosure for enabling sterilization gases to pass through the at least one aperture covered by the gas permeable barrier while preventing the flowable material from passing through the at least one of aperture. The gas permeable barrier is permeable to the sterilization gases and impermeable to the flowable material disposed within the fluid chamber of the enclosure.

A start of medicament delivery notification mechanism is presented where the notification mechanism is positioned within a housing of a medical device and includes a rear cap secured to a distal end of the housing, where the rear cap has a hollow tubular housing extending proximally from a distal end of the rear cap such that the tubular housing is cantilevered within and rotatably fixed relative to the housing and is parallel with a longitudinal axis of the housing. A rotator rotatably is positioned around the tubular housing such that rotator can rotate relative to the tubular housing from a first position to a second position, where the second position coincides with an initiation of a delivery of a dose of medicament. The rotator further has a contact surface that engages with and subsequently disengages from a corresponding contact surface located on the rear cap or on an inside surface of the housing.

In general, systems for administering a dmg are provided. In an exemplary embodiment, a dmg administration system includes a dmg administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The dmg administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

An injection device for injecting a substance into a body, including: a barrel provided with the substance a stopper in sliding engagement inside the barrel and an injection needle; a plunger rod coupled to the stopper and moveable in order to inject the substance, a locking clip fixed relative to the barrel and provided with at least two jaws engaging the plunger rod so as to prevent an injection movement of the plunger rod with regard to the barrel, and a needle shield including a triggering portion, the needle shield being configured in sliding engagement with respect to the injection needle, where the triggering portion is configured to open the locking clip when the needle shield moves from an initial position to a retracted position.

Provided is a device for injecting a fixed quantity of liquid medicine, to which a syringe may be mounted and which may inject the liquid medicine held in the syringe by a fixed quantity due to a user's pushing operation. The device for injecting the fixed quantity of liquid medicine is advantageous in that a user can operate the device with one hand to inject the fixed quantity of medicine into various areas, thus maximizing operability and convenience. Furthermore, the device is advantageous in that it is possible to maximize medicine delivery efficiency even when operated by a person who is not a medical staff not in a hospital but at home.

The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a body adapted to receive a medical container in a fixed position relative to the body. The injection device includes a spring-loaded piston rod translationally movable inside the body between a proximal rest position allowing inserting of the medical container in the body and a distal operative position wherein the piston rod engages a stopper of the medical container and pushes the stopper in the medical container. The injection device includes a blocking system comprising a locking member mounted on the body and configured to engage the piston rod. The piston rod includes a proximal end extending out of the body and configured to be pushed by the user in a distal direction to accelerate the movement of the piston rod to the distal operative position.

An injection device includes: a housing with a product container in which a stopper with a bearing face can be moved to a stopper end position and which, proximally to the stopper end position, has a minimum product container cross section; a drive configured to move the stopper, which includes a plunger rod with a drive face that contacts the bearing face; a plunger rod guide is arranged outside the product container and guides the plunger rod, with a plunger rod guide cross section adapted to a plunger rod cross section. The product container only incompletely guides movement of the plunger rod and the plunger rod cross section is not prevented from moving in a tilting direction by the minimum product container cross section, and a plunger rod centering aid a distal end of the plunger rod limits the movement of the plunger rod in the tilting direction.

An injection device includes a syringe barrel for holding medication, a collar positioned on a proximal end of the syringe barrel, a piston assembly including a piston arranged in the syringe barrel, and a rod member extending through the collar to the piston, and a blocking member arranged on the rod member. The piston assembly is movable distally relative to the syringe barrel in a priming stroke. The piston assembly is movable relative to the collar during the priming stroke of the piston assembly such that the blocking member longitudinally abuts the piston assembly and the collar at an end of the priming stroke of the piston assembly.

Devices and methods for use with syringes are disclosed. A plunger rod includes an outer housing having proximal and distal ends and a lumen between the ends, as well as an inner body axially slidable within the lumen between a first and second position. The inner body has a retention member extending therefrom. When the inner body is in the first position, the plunger rod has a first length, and, when the inner body is in the second position, the plunger rod has a second length greater than the first length. When the inner body is in the second position, the inner body is configured to be rotated relative to the outer housing until the retention member is received within the outer housing to preclude the inner body from moving in the axial direction.

Devices, systems, and methods for minimization of backlash in a syringe pump are described herein. Syringe pumps may comprise a syringe including a cylindrical body and a plunger, and a controller. The plunger may comprise a linear gear that may operably couple with a circular gear in the controller. The controller may be configured to bias the circular gear in a biasing rotational direction, thereby positioning the plunger to move towards a biasing translational direction. The methods may comprise determining a backlash compensation amount, determining a fluid transfer movement amount, moving at least one component of the syringe pump the backlash compensation amount and the fluid transfer movement amount in a first direction, and moving the at least one component of the syringe pump a biasing movement amount in a second direction opposite the first direction to re-engage the first gear and the second gear to minimize backlash.