Embodiments of the invention are directed to flush syringe assemblies comprising an integrated contamination-prevention device integrated with device connector flushing positioned so that the practitioner cannot forget to apply disinfectant. The flush syringe assemblies comprise a barrel with an elongate plunger rod disposed therein and a cap comprising a passageway. The plunger rod includes a stopper of which at least a portion can be embedded in the passageway of the cap to form a plug in the cap.

Embodiments of the invention are directed to flush syringe assemblies comprising an integrated contamination-prevention device integrated with device connector flushing positioned so that the practitioner cannot forget to apply disinfectant. The flush syringe assemblies comprise a barrel with an elongate plunger rod disposed therein and a cap comprising a passageway. The plunger rod includes a stopper of which at least a portion can be embedded in the passageway of the cap to form a plug in the cap.

A container for storing and mixing two components is provided. The container includes a body, a first plug, and a second plug. The body has a first end, a second end, and a bypass with a length L disposed between the first and second ends. The first and second plugs are slidably disposed in the body and define a first compartment. A second compartment is in the body between the second plug and the second end. The second plug has a first edge, a second edge, and a primary conduit extending therein, a plurality of secondary conduits extending from the primary conduit through the second plug. The primary conduit has a first opening. A distance D extends longitudinally from the first edge to the second edge and a distance E extends longitudinally from the first edge to the first opening. DL and E<L.

This disclosure is directed to a piston configured to be used with a dispensing syringe and a dispensing syringe having the piston. The piston has a body configured to be slidably positioned within an interior reservoir of the dispensing syringe. The body defining a wall that circumferentially surrounds the piston. The piston also has a wiper seal that extends outwardly and circumferentially from the wall. The wiper seal define a lip, a first portion, a second portion, and a junction that connects the first portion and the second portion. The second portion extends outwardly from the junction and away from the body to the lip.

The present invention provides a plunger head designed to absorb the increased pressure applied against it during heat sterilization to thereby minimize or prevent plunger head movement during autoclaving. The present invention provides the plunger head as part of a syringe or as part of a kit including a syringe, a plunger rod, and optionally, a pharmaceutical product fluid such as a contrast media. Some pharmaceutically-tolerable gas may be provided in the syringe with the product fluid.

The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10) having a tubular portion (12) with an inner thread, a piston rod (30) having a threaded portion (31) and a distal end, and a bearing (140) having a distal face and a proximal face. The bearing (140) comprises a retaining stem (142) protruding from the proximal face. The piston rod (30) comprises a distal portion having an outer diameter which is smaller than the inner diameter of the inner thread of the tubular portion (12) and comprising at its distal end at least one retaining clip (33, 33) engaging the retaining stem (142). The axial length of the tubular portion (12) is smaller than or equal to the axial distance between the proximal face of the bearing disc (141) and the distal end of the threaded portion (31) of the piston rod (30). During manufacturing of the device, the retaining clip (33, 33) engages the retaining stem (142) prior to the inner thread of the tubular portion (12) engages with the threaded portion (31) of the piston rod (30).

A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.

An injection device includes: a body for receiving a product, a needle and a piston attached to a piston rod movable between a storage position and an end-of-injection position. The device further includes a sleeve for protecting the needle which is movable between an initial position where the needle is uncovered and a final position where the needle is covered, as well as biasing means for moving the sleeve from its initial position to its final position and immobilization means for keeping the sleeve in its initial position. The piston rod includes a first portion and a second portion, the second portion being able to switch between a locked position in which the second portion is fixed to the first portion and an unlocked position in which the second portion is movable with respect to the first portion on a predetermined distance along the longitudinal axis of the piston rod.

A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.