A syringe plunger loop for improved aspiration and injection is disclosed herein. Generally, the loop disclosed herein improves both aspiration and injection by providing stability to the aspiration or injection finger or thumb of the injector. The loop disclosed herein may be integrally attached to the plunger of the syringe. Alternatively, the loop may be a separate piece from the syringe that may be removably attached to the plunger.

A syringe plunger loop for improved aspiration and injection is disclosed herein. Generally, the loop disclosed herein improves both aspiration and injection by providing stability to the aspiration or injection finger or thumb of the injector. The loop disclosed herein may be integrally attached to the plunger of the syringe. Alternatively, the loop may be a separate piece from the syringe that may be removably attached to the plunger.

A component for a syringe is disclosed. The component has formed a structure which has a friction-reducing effect due to its shape in the syringe. The component can be, for example, a cylinder, a piston or a seal for the syringe. The structure comprises, for example, elevations or depressions which have a linear, punctiform, elliptical or polygonal design. Also disclosed is a syringe which has at least one such component. The use of a component with a friction-reducing structure makes it unnecessary to use an additional friction-reducing coating, for example silicone, which can lead to undesirable effects on the medicament to be administered with the syringe.

Drive systems for a drug delivery device are provided. The drive systems can be positioned within a container that stores a liquid drug to be delivered to a user. The drive systems can be coupled to a plunger positioned within the container. The drive systems can be incrementally advanced to drive the plunger further into the container, thereby expelling a portion of the stored liquid drug from the container for delivery to the user. The container can be any type of container including a pre-filled, standardized drug cartridge. The drive systems and container can be components of a wearable drug delivery device.

A needle syringe has a plunger and a needle for filling and dispensing liquid from the cavity. The cavity has finger clip with movable locking pins. The plunger has at least one set of grooves corresponding to a specific dosage for the needle syringe, the specific dosage of the groove being demarked by a marking ledge that indicates a change to a deeper depth section of the groove. The locking pins are configured to rest in the at least one set of grooves, such that when the plunger is removed, the locking pins pass within a first shallow section of the groove, pass over the ledge, and continue to pass in the deeper depth section of the groove. When the plunger is depressed in a first partial dispensing movement, the locking pins pass in the deeper depth section of the groove until the plunger depression is temporarily locked when the locking pins reach the ledge, where the dose remaining in the cavity is the specific dosage.

A method for administering a medicament suitable for treating a migraine or cluster headache to a patient in need thereof includes placing a mounting surface of a fluid delivery apparatus with the medicament in contact with at least a portion of the skin of said patient. A flow rate of the medicament from the fluid delivery apparatus is adjusted such that the medicament is delivered to the patient for at least a predetermined time period. The fluid delivery apparatus includes a controller assembly having a body component defining an axis and a plunger component slidably coupled to the body component. The plunger is positionable between a first position in which the plunger is nearest to the body component and a second position in which the plunger component is furthest from the body component. A bias assembly is positioned between the body component and the plunger component. The bias assembly is configured to apply a two stage force profile to the plunger component. Also disclosed is a method for administering sumatriptan to a patient in need thereof such that the C.sub.max, T.sub.max and AUC are within predetermined, therapeutically effective values.

An improved hypodermic syringe including finger-holding surfaces that substantially or completely surround the operator finger and include an interior tapered portion to better engage a finger, which facilitates one-handed use by allowing the same hand that holds the syringe to operate the plunger conveniently to accomplish both the distal (injecting) stroke and the proximal (aspirating) stroke.

The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring. The clutch comprises a first ring of crown teeth on the drive member and a second ring of corresponding crown teeth on the driven member with each crown tooth having in the clockwise and the anti-clockwise direction different ramped tooth angles such that the teeth are allowed to override each other in the de-coupled state of the clutch with a different resistance in the clockwise and the anti-clockwise direction.

A syringe is provided having a hub with an orifice, first and second barrels having interior surfaces to form respective lumens, a slider, and an optional test indicator. The first and second barrels slideably receive respective first and second plungers for movement therein. The slider is operable to provide a fluidly communicative path between the orifice of the hub and the first and second barrel lumens. The optional test indicator is responsive to at least one characteristic of bodily fluid, the test indicator positioned to be exposed to any bodily fluid drawn into the first barrel lumen and visible from an exterior of the first barrel.

A segmented piston rod for an injection device includes multiple segments joined together via a hinge located on one side of each segment. The piston rod can be bent in one direction by articulating subsequent hinges while an axial force can be transmitted by the segmented piston rod to the stopper when the subsequent hinges are closed and the segments abut each other opposite to the one side of the hinge. The segmented piston rod is secured against rotation relative to the housing around the longitudinal axis of the segmented piston rod. The segmented piston rod has a last element which abuts the stopper in the reservoir and a first segment which is opposite to the last segment. The first segment is includes an internal thread matching an external thread of a drive sleeve and rotation of the drive sleeve advances the piston rod towards the stopper of the reservoir.