The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion. Each of the first leg and the second leg has a distal portion extending from the inclined section, the distal portions being radially flexible and extending radially outwards in an axial direction away from the proximal portions to allow the gripping member to receive a medicament delivery member shield between the distal portions. The gripping member and an inner wall of the channel are configured to engage to retain the gripping member in the inner cap structure. Each distal portion is provided with a medicament delivery member shield gripper configured to engage with a medicament delivery member shield when the gripping member engages with the inner wall of the channel and the gripping member has received a medicament delivery member shield causing the proximal portions and the distal portions to flex radially inwards.

A puller assembly for removing a shield from around a needle of a syringe. The puller assembly includes a grip component and a cap. The grip component has a tubular body defining an interior hollow which axially receives the shield. The tubular body has a slit that allows it to be forcibly shifted from a first arrangement to a second arrangement to change the size of the interior hollow. The tubular body includes a radial inner face with at least one radial inward projection for directly engaging the shield. The cap is grippable by a user. The grip component is held by the cap when inserted within a cavity of the cap during manufacturing installation, and when so held at least one radial inward projection of the grip component engages the shield for removal of the shield from around the needle when the cap is moved. A method of mounting a puller assembly to a shield around a needle is also disclosed.

A safe auto-needle device for injection, comprising: a main housing; a syringe-support for receiving a disposable prefilled syringe; said syringe comprises: a piston; a proximal end; and a distal end terminating in a needle covered by a needle sheath (NS); a drive mechanism for advancing said syringe-support distally towards an injection site; a tubular needle shield; moveable from: a needle covering position, to partially exposed, to needle irreversibly concealed; said generally tubular needle shield comprising a distal end for contacting an injection site, and a proximal end; a spring urging distal movement of said needle shield; and said needle shield comprising a spring seat; an NS remover, designed to mate with and irreversibly grip said NS, for removal of said NS prior to injection; a locking mechanism preventing premature advancement of said needle; a plunger rod for engaging said piston, wherein depressing of said plunger is manually controllable; wherein in use of said device, said NS remover is removed; said distal end of said needle shield is pressed upon an injection site, releasing said locking mechanism, and driving said syringe-support and said syringe, distally until needle penetration; and upon depressing of said plunger, a medicament may be injected. The invention additionally provides a novel two-component NS remover.

This disclosure relates to a cap assembly for a medicament delivery device that has a cap body arranged to be connected to a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel with a friction fit and to receive a medicament delivery member shield. The gripping member has a first leg, a second leg, and a transverse portion extending between the first leg and the second leg, which transverse portion defines the leading edge of the gripping member when received by the channel.

A fluid injection device having a syringe body, a needle, and a needle protection device removable from the injection device and having a substantially flexible or deformable inner body and a substantially rigid outer body. In the stored position the inner body closes the dispenser orifice of the needle and the outer body co-operates with the injection device to fasten the protection device on the injection device. The protection device includes a protection system against accidental pricking, having protective flaps that are integral part of the outer body and movable between a covering position in which they cover the needle, and an open position in which the needle is uncovered. The protection system has a control ring that slides over the outer body so as to move the flaps from their covering position to their open position, before injection, and from their open position to their covering position, after injection.

Systems and methods encourage users to rotate injection sites and avoid lipodystrophy. Sleeves and/or lost-tooth gear dials and/or microswitches in or on injection pens or their caps, on vials, and on other portable devices manually adjust an indicator before or after an injection to show a current or next injection site in accordance with a site rotation plan. Injected medicine packaging and related printed indicia encourage site rotation. Optical devices employing optical mouse or projection technology help locate and/or distribute injection sites within a body area. A mobile phone app tracks injections and locations to select next injection site, and can use imaging to locate a target injection site and optionally diagnose lipodystrophic conditions and record them. Tactile and print media educational tools are presented to help users palpate and identify lipos in body areas having injection sites.

An injection system includes a handle assembly with a handle body having an outer surface surrounding a handle body interior and a plunger extending therethrough. A tubular handle collar is telescopically received in the handle body exterior and is axially movable with respect to the handle body. A syringe housing assembly is selectively connectable to the handle assembly and includes a syringe housing and a tubular syringe sleeve telescopically received through a distal end of the syringe housing and axially movable with respect thereto. The syringe housing has an exterior side surface surrounding a syringe housing interior configured to receive at least a portion of a syringe. The syringe sleeve has a proximal end, a distal end with a skin contact surface, and a generally cylindrically-shaped outer surface.

A device for administering a fluid medicament by injection comprises a dosing portion (1) with a collapsible reservoir (10). The reservoir (10) has a maximum volume in an extended state and a minimum volume in a collapsed state. Prior to injection, the reservoir (10) is in the extended state and contains a liquid to be administered, and the reservoir (10) is biased towards the collapsed state. The device further comprises a needle (2), wherein a lumen (20) of the needle (2) is in fluid communication with the reservoir (10). The device further comprises a shield portion (3) with a plug (30). Prior to injection, the shield portion (3) is in a deployed position where the plug (30) blocks the lumen (20) of the needle (2). The shield portion (3) is adapted to move in response to an actuation force from the deployed position to a retracted position where the lumen (20) of the needle (2) is open, thereby causing the reservoir (10) to shift to the collapsed state to expel the liquid through the needle.

An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.

The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support comprises a projecting portion, which projects from the syringe support in a distal direction and a flexible portion which axially adjoins the projecting portion. The flexible portion is adapted to axially bias the syringe in the distal direction within the housing. The disclosure further relates to an autoinjector.