A method for producing an injection device are disclosed. The injection device comprises a hollow needle which is positioned in a basic body of the injection device. The injection device is produced by a two-stage injection process. At least one first slider and a second slider are provided in a tool block. Together with the tool block, the first slider and the second slider form free space, which defines a shape of a pre-injection molded part of the basic body of the injection device.

The present invention provides devices and methods for establishing aseptic connections between two or more components or subassemblies. The devices may be used in medical devices such as drug delivery pumps (10). In some embodiments, a connection is made between a drug container (50, 1050, 2050) and a fluid pathway connection assembly (300, 1300, 2300). The fluid pathway connection assembly may include a connection hub (312, 1312, 2312), a piercing member (316, 1316, 2316), and a piercing member retainer (314, 1314, 2314). The assembly may further include a first film (318, 1318, 2318) covering a cavity (312A, 1312A, 2312A), thereby maintaining the aseptic condition of the cavity. The drug container may hold a fluid drug and include a pierceable seal (326, 1326, 2326). A second film (322, 1322, 2322) may cover a recess (328, 1328, 2328) formed by the seal and thereby maintain the aseptic condition of the interior of the chamber. The piercing member may be caused to pierce the first and second film and the pierceable seal to open a fluid pathway for delivery of the fluid drug through the fluid pathway connection assembly.

An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

A hollow needle, for use in medical and other areas where thin hollow needles are used to inject or aspirate fluids and gases, is provided and comprises of a thin, rigid tube body that is open on both ends and throughout the length with one sharp end. A flexible section is provided, either as part of the needle or as an addition at its proximal end allowing the needle to be oriented such that the needle central axis is non-colinear and non parallel to the central axis of the needling system. Depending upon the desired use, needle orientation relative to the central axis can be limited from a conical volume to a planar or multi planar angular orientations. The needling system so configured advantageously allows the user to circumvent an obstacle and or obstacles that otherwise inhibit direct linear access to a point-of-interest by providing a device that can fit around or between obstructions providing optimal direct path towards the desired therapy delivery point.

An injector device comprises a needle support member for supporting a distal end of a needle within a collar region of the device. On insertion of the neck of a drug cartridge into the collar region, the tip of the needle pierces a septum in the drug cartridge and is thereafter supported by the septum. The needle support member is then displaced by the drug cartridge as it moves further into the collar region. The displacement may comprise hinging or sliding of the support member. By supporting the needle as it pierces the septum and by providing controlled resistance to rapid or violent insertion of the drug cartridge, the needle support member enables a single, fine needle to be used for both the distal end and the proximal end without buckling, even if the needle is curved so that the two ends are mutually inclined.

A syringe cartridge comprising a reservoir part and an extension extending from said reservoir part, said extension defining a fluid path and comprising a molding and a first needle extending from said molding, the extension turning to a finite angle with respect to an axis of said reservoir part and wherein at least part of said first needle is likewise at said finite angle, at least some of said part of said first needle at said finite angle being enclosed within said molding of said fluid path.

A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

A tool and a method for producing an injection device are disclosed. The injection device comprises a hollow needle which is positioned in a basic body of the injection device. The injection device is produced by a two-stage injection process. At least one first slider and a second slider are provided in a tool block. Together with the tool block, the first slider and the second slider form free space, which defines a shape of a pre-injection molded part of the basic body of the injection device.

A drug delivery device may include sterile needle covered by removable a sterility preserving protector. The device optionally includes skin contact surface and a needle protector for preventing a stick hazard upon removal of the skin contact surface from an injection site or angle without Removing completely. Optionally, the needle protector may include a shield that interferes with replacement of the needle protector. In some embodiments, the needle cover may interfere with deployment of the needle protector.

A syringe cartridge comprising a reservoir part and an extension extending from said reservoir part, said extension defining a fluid path and comprising a molding and a first needle extending from said molding, the extension turning to a finite angle with respect to an axis of said reservoir part and wherein at least part of said first needle is likewise at said finite angle, at least some of said part of said first needle at said finite angle being enclosed within said molding of said fluid path. A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

The present invention provides devices and methods for establishing aseptic connections between two or more components or subassemblies. The devices may be used in medical devices such as drug delivery pumps (10). In some embodiments, a connection is made between a drug container (50, 1050, 2050) and a fluid pathway connection assembly (300, 1300, 2300). The fluid pathway connection assembly may include a connection hub (312, 1312, 2312), a piercing member (316, 1316, 2316), and a piercing member retainer (314, 1314, 2314). The assembly may further include a first film (318, 1318, 2318) covering a cavity (312A, 1312A, 2312A), thereby maintaining the aseptic condition of the cavity. The drug container may hold a fluid drug and include a pierceable seal (326, 1326, 2326). A second film (322, 1322, 2322) may cover a recess (328, 1328, 2328) formed by the seal and thereby maintain the aseptic condition of the interior of the chamber. The piercing member may be caused to pierce the first and second film and the pierceable seal to open a fluid pathway for delivery of the fluid drug through the fluid pathway connection assembly.