Nocilytic devices and methods for treatment of dyspareunia are provided. In particular, a device is provided, which inserts intravaginally with inflatable balloons to map the location of pain during application of force exerted against/on the luminal side of the vaginal wall and/or vulva of a human patient, or sensors to detect locations for application of nocilytic therapy.

The present invention relates to adaptor (30) for a drug delivery device having a reservoir (12) and a longitudinal tip (20), the adaptor (30) comprising a distal part defining a connecting ring (31) intended to receive a connector, and a proximal part defining a mounting ring (33) having an inner surface (34), the mounting ring (33) being shaped and configured such that, when the adaptor (30) is mounted around the longitudinal tip (20) of the drug delivery device, at least one annular space (38) is created between said inner surface (34) of the mounting ring (33) and said outer surface (20a) of the longitudinal tip (20), said at least one annular space (38) being able to accommodate an adhesive layer (40) in order to bond said adaptor (30) to said longitudinal tip. The invention further relates to a drug delivery device comprising such an adaptor.

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

A sealed and cryoresistant device for injecting a solution, the device being designed to be associated with a needle for subsequent injection of the solution and including an injection body, a plug and a plunger head. The injection body includes a first, proximal end closed in a sealed manner by the plunger head and a second, distal end closed in a sealed manner by the plug. The plug is held on the injection body by a fastening and includes a breakable portion allowing a needle to be mounted, the plug being a divisible plug, the separation of a divisible portion releasing an element for fastening an injector including a needle. The materials forming the device are cryoresistant.

An apparatus for injecting a fluid includes: an injector including a cylindrical container, a coupling portion, and a peripheral section; a needle assembly including a needle and a hub defining a contact area, the coupling portion configured to be coupled with the hub; and a needle retention device including a needle-retainer portion having a finger configured to radially extend over at least a part of the contact area of the hub, a container-contact portion defining a first opening configured to be attached in a form-fitting way onto the peripheral section of the container. When the apparatus is in its operational state, the hub of the needle assembly is coupled to the coupling portion, the container-contact portion is attached to the container, and the finger of the needle-retainer portion extends over the contact area of the hub when the needle retention device is in its retaining position.

A syringe assembly includes a syringe body, needle assembly, retaining clip, gasket, needle latch, and needle hub. The syringe body has a syringe interior, longitudinal axis, proximal and distal ends, and needle attachment interface disposed at the distal end thereof. The gasket is configured to be compressed to provide a liquid-tight seal around an outer diameter of the needle assembly and the distal end of the syringe body. The needle latch assembly includes first and second latching tabs configured to retain the needle assembly in a close state and to be plastically deformed to an open state to release the needle assembly, and a gasket backstop configured to provide a flat surface for compression of the gasket, where the first and second latching tabs are spaced apart from the gasket such that neither of the first and second latching tabs contact the gasket during compression of the gasket.

The present invention relates to an assembly comprising an injection device comprising a container for a product, wherein the container includes a distal tip encompassing a channel providing a passageway for transferring the product, and an adaptor mounted onto the distal tip. The assembly further includes a heat-shrinkable film covering at least part of the container and at least part of the adaptor, wherein the heat-shrinkable film maintains the adaptor blocked in rotation and in translation relative to the container when the heat-shrinkable film is in heat-shrunk condition.

The present disclosure relates to a rigid sensor stopper adapted for use in a drug delivery device. In one implementation, a rigid sensor stopper may include a transducer, a power source, a rigid molding or casing, and at least one elastomeric seal. The molding may be formed from overmolding or insert molding, and the casing may be formed from injection molding, machining, or forged casing. The at least one elastomeric seal may include at least two o-rings.

The present invention relates to adaptor (30) for a drug delivery device having a reservoir (12) and a longitudinal tip (20), the adaptor (30) comprising a distal part defining a connecting ring (31) intended to receive a connector, and a proximal part defining a mounting ring (33) having an inner surface (34), the mounting ring (33) being shaped and configured such that, when the adaptor (30) is mounted around the longitudinal tip (20) of the drug delivery device, at least one annular space (38) is created between said inner surface (34) of the mounting ring (33) and said outer surface (20a) of the longitudinal tip (20), said at least one annular space (38) being able to accommodate an adhesive layer (40) in order to bond said adaptor (30) to said longitudinal tip. The invention further relates to a drug delivery device comprising such an adaptor.

An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.