A percutaneous medication device, comprising a syringe to be filled with medical liquid and a needle formation attached to a leading-end of the syringe is provided. The needle formation comprises a needle formation body, from the surface of which a needle projects and a cover portion covers a leading-end of the needle formation body. The needle is inserted into a through-hole formed at the leading-end of the needle formation body and fixed by a fixation member. The needle formation body is mated to the cover portion, a space is formed between an inner surface of the cover portion and the leading-end of the needle formation body, and the needle projects from the leading-end surface of the cover portion through a needle insertion hole formed at the leading-end of the cover portion.

A needle hub assembly for a pen needle includes a needle hub, an inner shield and an outer cover. The open end of the outer cover is closed by a removable seal to access the needle hub. The needle hub has a body with a shoulder and a tower extending from the body for supporting a cannula. The inner shield fits over the tower and the cannula and includes a flange that has an outer dimension complementing the outer dimension of the needle hub and contacts the shoulder of the needle hub in the assembled condition. The outer cover encloses the needle hub and the inner shield and includes a stop member on an inner surface that contacts the flange of the inner shield to capture the inner shield between the shoulder of the needle hub and the outer cover.

The invention relates to a glass syringe-side assembly element for providing an interface element between a glass syringe including on its front side a syringe cone part with a syringe needle and including on its rear side a flange part and a glass syringe operating means, where the assembly element can be arranged on the outer contour of the glass syringe, and where the assembly element can be secured to the assembly element relative to the syringe needle in front of the flange part on the glass syringe such that a reference point of the assembly element is always at a defined distance from the needle tip of the syringe needle.

Disclosed is a pen needle including: a needle; a needle hub which comprises a coupling structure, which can be screw-coupled to a body, holds the needle and has protrusions formed on a supporting surface; a spring which has one side supported on the supporting surface and provides resilience; a plunger which has a plurality of resilient blades, which can be folded or unfolded, and has a hollow through which the needle passes; a small cap which is supported on the other side of the spring and receives the plurality of blades such that the plurality of blades can be received therein or be dislodged; and a medium cap which is coupled to the small cap, accommodates the small cap such that the small cap can move, and has serrations corresponding to the protrusions.

A syringe and detachable needle assembly having reduced dead space features includes an elongate syringe barrel having open distal end including a collar and a distally facing annular surface projecting inwardly from the collar. A needle assembly includes a hub having a proximally facing annular surface and an outwardly projecting annular sealing ring positioned distally from the surface. The needle assembly also includes a cannula having a lumen therethrough connected to the distal end of the hub. Structure is provided for engaging the hub to the barrel resulting in the annular surface of the barrel contacting the annular surface of the hub to form a primary seal between said barrel and said hub and the annular sealing ring contacting the collar to form a secondary seal between the barrel and the hub.

Junction assemblies for joining intravenous (IV) devices to tubing are provided. A junction assembly includes a component connector and a shaped memory polymer (SMP) member formed of a shape changing material. The junction assembly allows movement of the tube along the component connector when the SMP member is in an expanded state and the junction assembly retains the tube securely against the component connector when the SMP member is in a contracted state. The shape changing material changes to one of the expanded state and the contracted state upon being subjected to an external stimuli. Methods of assembling junction assemblies are also provided.

Junction assemblies for joining intravenous (IV) devices to tubing are provided. A junction assembly includes a component connector and a shaped memory polymer (SMP) member formed of a shape changing material. The junction assembly allows movement of the tube along the component connector when the SMP member is in an expanded state and the junction assembly retains the tube securely against the component connector when the SMP member is in a contracted state. The shape changing material changes to one of the expanded state and the contracted state upon being subjected to an external stimuli. Methods of assembling junction assemblies are also provided.

The invention relates to a pre-filled syringe, an auto-injector device comprising such pre-filled syringe, a method of administering a pharmaceutical composition with such auto-injector device, and a manufacturing method for such auto-injector device. The pre-filled syringe comprises a container and a needle. The container is filled with a pharmaceutical composition comprising epinephrine, a buffer, and water. The buffer is configured to buffer in a pH range between 3 and 4. The needle is adhered to the container by means of a urethane acrylate or urethane methacrylate acrylic light cure adhesive, which is configured to provide a pull out resistance of the needle relative to the container which is between 30 N to 100 N, preferably between 50 N to 70 N, more preferably greater than 60 N after 90 days exposure to the pharmaceutical composition at 40° C. and 75% relative humidity (RH). In an example, the pharmaceutical composition is for the treatment of an anaphylactic event.

A needle-bearing hub for a pen needle is provided with a distal patient-facing side having an enlarged surface for contact with the subject's skin. The enlarged surface is provided with a radius of curvature that increases the likelihood that the needle reaches full injection depth when an injection is performed at an inclined angle with respect to the surface of the skin and with to the desired depth less discomfort to the patient.

The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.