An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

User-friendly attachment mechanisms for pen needles provide improved handling and ease of use, including locking installation and removal features and sensory feedback when a needle-bearing hub is seated on a pen. Embodiments include a needle-bearing hub includes a circumferentially oriented flexible tab that engages a radially inward rib on an outer cover to assist in attaching a pen device to the pen needle.

A needle-bearing hub for a pen needle is provided with a distal patient-facing side having an enlarged surface for contact with the subject's skin. The enlarged surface is provided with a radius of curvature that increases the likelihood that the needle reaches full injection depth when an injection is performed at an inclined angle with respect to the surface of the skin and with to the desired depth less discomfort to the patient.

A needle-bearing hub for a pen needle is provided with a distal patient-facing side having an enlarged surface for contact with the subject's skin. The enlarged surface is provided with a radius of curvature that increases the likelihood that the needle reaches full injection depth when an injection is performed at an inclined angle with respect to the surface of the skin and with to the desired depth less discomfort to the patient.

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

A needle-equipped outer cylinder includes: a needle tube; a joining member comprising: a needle tube accommodation hole that accommodates a proximal end side portion of the needle tube and penetrates the joining member from a distal end of the joining member to a proximal end of the joining member, and a joining outer peripheral portion provided on an outer peripheral portion of the needle tube accommodation hole; and an outer cylinder member comprising: a distal end joint that comprises an inner cavity that receives the joining outer peripheral portion of the joining member from a distal end side, and a projection located at a proximal end portion of the inner cavity and projecting into the inner cavity. The joining member comprises, at a proximal end portion of the joining member, an abutment portion that abuts the projection of the outer cylinder member.

Method for coating a glass syringe body for a hypodermic pre-filled glass syringe, wherein at least one emulsion and/or one solution containing at least one layer-forming substance is applied to at least one inner surface of the hypodermic pre-filled glass syringe, which defines an axial direction, wherein at least a partial surface of the inner surface in a syringe cone of the pre-filled glass syringe is subsequently exposed to a plasma, wherein a negative pressure source is arranged in relation to the syringe cone in the axial direction opposite the atmospheric-pressure plasma source, wherein a negative pressure of less than atmospheric pressure is provided by means of the negative pressure source.

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

A hypodermic interface assembly is disclosed. The hypodermic interface assembly includes a hub, a cannula, and a cannula carrier. The cannula carrier is non-removably-connected to the cannula. The cannula carrier is controllably separable from the hub.