The control-monitor, used in combination with a percussive ventilation breathing head and internal reciprocating injector shuttle, includes in a casing a generator, sensory pulse amplitude, frequency and MAP modules and a gas amplitude and pulsatile frequency control knobs. First and second AMP control indicia include a bent conical AMP indicia (a wide span indicating greater amplitude, a narrow span indicating lesser amplitude) and a single waveform with an adjacent double-headed arrow vertical line. First and second F control indicia include a bent conical F indicia (a wide span indicating greater F and a narrow span indicating lesser F) and multiple waveforms with an adjacent double-headed arrow horizontal line.

Systems and methods are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a housing defining a sump, the sump configured to hold a self-contained supply of liquid anesthetic agent, a heating element electrically coupled to an electrical mating component, a gas inlet passage and a gas outlet passage, a manifold fluidically coupled to the gas inlet passage and the gas outlet passage, the manifold coupled to the housing and forming a gas-tight seal with the sump, and a quick disconnect pneumatic system coupled to the gas inlet passage and the gas outlet passage, sealing the gas inlet passage and the gas outlet passage from atmosphere.

A breath-enhanced nebulizer adapted for use in administering an aerosolized pharmaceutical composition to a patient by inhalation wherein the patient is connected to a mechanical ventilator is disclosed. The nebulizer has a Venturi driven by a nebulizer air supply that draws a solution of a pharmaceutical composition into a shear zone where the solution is atomized. The Venturi effect is amplified by the internal configuration of the nebulizer to increase the rate of nebulization of drug. Optionally, breath-actuated nebulization is used, employing a pressure sensor interposed between the nebulizer and mechanical ventilator that controls the nebulizer air supply, such that nebulizer air and concomitant nebulization only occurs during the inhalation phase of a breathing cycle.

A ventilator includes an enclosure, a tubing configured to receive an input gas, and a flow outlet airline in fluid communication with the tubing. The flow outlet airline includes an airline outlet. The ventilator further includes a breath detection airline including an airline inlet. The airline inlet is separated from the airline outlet of the flow outline airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The ventilator includes a controller in electronic communication with the pressure sensor and an internal oxygen concentrator in fluid communication with the tubing. The internal oxygen concentrator is entirely disposed inside the enclosure.

Systems and methods may include a gas source, a gas delivery circuit, and a nasal interface allowing breathing ambient air through the nasal interface. A gas flow path through the nasal interface may have a distal gas flow path opening. A nozzle may be associated with a proximal end of the nasal interface a distance from the distal end gas flow path opening. At least a portion of an entrainment port may be between the nozzle and the distal end gas flow opening. The nozzle may deliver gas into the nasal interface to create a negative pressure area in the gas flow path at the entrainment port. The nasal interface and the nozzle may create a positive pressure area between the entrainment port and the distal end gas flow path opening. Gas from the gas delivery source and air entrained through the entrainment port may increase airway pressure or lung pressure or provide ventilatory support.

A system for reducing airway obstructions of a patient may include a ventilator, a control unit, a gas delivery circuit with a proximal end in fluid communication with the ventilator and a distal end in fluid communication with a nasal interface, and a nasal interface. The nasal interface may include at least one jet nozzle, and at least one spontaneous respiration sensor in communication with the control unit for detecting a respiration effort pattern and a need for supporting airway patency. The system may be open to ambient. The control unit may determine more than one gas output velocities. The more than one gas output velocities may be synchronized with different parts of a spontaneous breath effort cycle, and a gas output velocity may be determined by a need for supporting airway patency.

Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: first and second air inlet openings for receiving external air a first air outlet opening for providing the external air to a first opened blister pocket and a first medicament inlet opening for receiving air-entrained medicament from the first opened blister pocket, the first air outlet opening and the first medicament inlet opening being arranged side-by-side to enable simultaneous communication with the first opened blister pocket; a second air outlet opening for providing the external air to a second opened blister pocket and a second medicament inlet opening for receiving air-entrained medicament from the second opened blister pocket, the second air outlet opening and the second medicament inlet opening being arranged side-by-side to enable simultaneous communication with the second opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the first and second opened blister pockets to the user, the first and second medicament inlet openings being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The first and second air inlet openings are fluidly connected to the first and second air outlet openings by respective first and second air conduits in the manifold component, wherein the air conduits are separately provided so that the external air from each of the first and second air inlet openings does not mix with the external air from the other of the first and second air inlet openings before reaching the first and second opened blister pockets.

The present invention provides for an improved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.

A flow generator for generating a mixed oxygen air flow, the flow generator including a body having a first inlet, a second inlet, an outlet, and one or more inner surfaces that define a first inner chamber in fluid communication with the first inlet and the second inlet, a second inner chamber in fluid communication with the first inner chamber, and a third inner chamber in fluid communication with the second chamber and the outlet of the body. The flow generator includes a connector disposed in the first inlet and a nozzle disposed within at least a portion of the connector and extending into the first inner chamber. The flow generator further includes an adapter engaged to the nozzle to form a fluid tight path such that the adapter connects to an external oxygen source and transports oxygen into the nozzle.

A chilled-air inhaler device for the alleviation of respiratory symptoms includes a body containing a hollow chamber through which air is forced or drawn past at least an air-chilling surface. In an embodiment the air-chilling surface may include water ice. Connected to the body and hollow chamber at one end is a mouthpiece including an opening that connects from environmental air outside of the hollow chamber to the hollow chamber. Connected to the hollow chamber at a second end is an inlet which connects to a source of air. In an embodiment, the inlet may connect to an external device such blower or nebulizer.