An example aerosol delivery device includes a mouthpiece having an airflow outlet, and an airflow passage extending between an airflow inlet and the airflow outlet. The example aerosol delivery device further includes a housing configured to receive a cartridge that includes an aerosolizable substance and a vapor element configured to heat the aerosolizable substance, and an internal power source configured to provide electrical power. The example aerosol delivery device further includes a controller coupled to the internal power source to receive a portion of the electrical power and configured to, when the cartridge is installed at the housing, cause the vapor element of the cartridge to heat the aerosolizable substance to release an aerosol into the airflow passage during an inhalation through the airflow outlet, and a connector configured to receive power from an external source to recharge the internal power source.

A breathable gas inlet control device permits flow regulation at the inlet of a flow generator for a respiratory treatment apparatus such as a ventilator or continuous positive airway pressure device. The device may implement a variable inlet aperture size based on flow conditions. In one embodiment, an inlet flow seal opens or closes the inlet to a blower in accordance with changes in pressure within a seal activation chamber near the seal. The seal may be formed by a flexible membrane. A controller selectively changes the pressure of the seal activation chamber by controlling a set of one or more flow control valves to selectively stop forward flow, prevent back flow or lock open the seal to permit either back flow or forward flow. The controller may set the flow control valves as a function of detected respiratory conditions based on data from pressure and/or flow sensors.

A ventilator, or a breathing assistance apparatus, is disclosed to ventilate patients who may have breathing difficulties, said device comprising a inspiratory pressure control duct configured to be immersed in a first body of fluid; a positive end-expiratory pressure control duct configured to be immersed in a second body of fluid; at least one valve connected to the peak inspiratory pressure control duct and to the positive end-expiratory pressure control duct, and at least one controller communicably connected to the valve to control rate of cycling of the valve, thereby controlling number of breaths per minute, and to control the duration of peak inspiratory pressure also known as inspiratory time.

This invention provides ventilators that provide superior air-oxygen mixing and gas delivery. The ventilators that supply a gas mixture to the lungs of a subject. The gas mixture comprises a first gas (e.g. oxygen) and a second gas (e.g. ambient air). The ventilators comprise a first gas inlet, a second gas inlet, flow modulator of the first gas, a flow modulator of the second gas, a junction configured to mix the first gas and the second gas, a patient interface configured to deliver the gas mixture to a subject, a pressure sensor, a plurality of flow sensors comprising at least a first flow sensor and a second flow sensor, and at least one controller configured for obtaining data from the pressure sensor and flow sensors and controlling the flow modulators to provide a gas mixture having a target pressure and a target oxygen content.

A respiratory assistance device including a respiratory interface device configured to be worn by a user and deliver a gas, a gas temperature measurement unit configured to measure a gas temperature that is a temperature of the gas, a warming unit configured to warm the gas, and a temperature change unit configured to change the gas temperature by controlling the warming unit. The respiratory assistance device can administer comfortable respiratory assistance even during sleep.

Systems and methods are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a housing defining a sump, the sump configured to hold a self-contained supply of liquid anesthetic agent, a heating element electrically coupled to an electrical mating component, a gas inlet passage and a gas outlet passage, a manifold fluidically coupled to the gas inlet passage and the gas outlet passage, the manifold coupled to the housing and forming a gas-tight seal with the sump, and a quick disconnect pneumatic system coupled to the gas inlet passage and the gas outlet passage, sealing the gas inlet passage and the gas outlet passage from atmosphere.

A ventilator system, comprising: an inhalation pathway comprising an ambient air inlet, a bi-directional emergency valve, and a dynamic blower; and an exhalation pathway comprising a bi-directional exhalation valve and an exhalation port; wherein when a blockage occurs in the inhalation pathway, ambient air can be drawn from the exhalation port and through the bi-directional exhalation valve, and during exhalation exhalant exits the ventilator through the bi-directional exhalation valve and the exhalation port; wherein when a blockage occurs in the exhalation pathway, inhalant is delivered by the dynamic blower, and during exhalation the dynamic blower lowers its speed or stops and the exhalant exits the ventilator through the bi-directional emergency valve, the dynamic blower, and the ambient air inlet.

There is provided a ventilator to ventilate an airway of a patient. The ventilator has a conduit having an inlet and an outlet, said outlet configured to be connected to said airway; a gas delivery element in fluid communication with said inlet, said gas delivery element configured to deliver air in a sequence of ventilation cycles, each ventilation cycle defined by a corresponding tidal volume to be delivered to said airway via said conduit, each tidal volume corresponding to a difference between a start volume and an end volume of said gas delivery element for that ventilation cycle; a pressure sensor monitoring pressure within said conduit; a controller communicatively coupled to said gas delivery element and said pressure sensor, said controller performing reducing said tidal volume between a first ventilation cycle and a successive second ventilation cycle contingent upon said pressure exceeding a pressure threshold in said first ventilation cycle.

A device (102) provides respiratory treatment for SDB (including mild OSA) and other respiratory conditions. A flow generator warms and humidifies gas at controlled flow levels. For example, the device (102) delivers breathable gas to the upper airway at flow rates of about 10-35 Liters/minute. Levels of flow rate, temperature and/or humidification of the device may be automatically adjusted in response to the detection of SDB events. The device may also automatically deliver adjustments of any of the levels in accordance with detected phases of respiratory cycles. In sane embodiments, the device automatically delivers distinct levels to either of the nares based on independent control of flow to each nare. A warm-up procedure controls temperature and humidity at a desired target during a ramp-up of flow to the set therapy level. A cool-down procedure controls temperature above the dewpoint to avoid condensation internal to the device and patient interface.

A ventilation machine is disclosed that includes a conduit interface configured to be connected to a respiratory system of a human or animal patient, an air flow generator configured to deliver air through the conduit interface into the respiratory system of the patient, a processing unit in communication with the air flow generator and configured to control the airflow generator to deliver air into the respiratory system of the patient according to a breathing scheme, and an induction device for activating a diaphragm of the patient. The induction device is in communication with the processing unit. The processing unit is configured to control the induction device to activate the diaphragm in coordination with the breathing scheme.