A combination positive airway pressure (PAP) or continuous positive airway pressure (CPAP) and resuscitation system and related methods. The systems can be well-suited for use in providing CPAP therapy for a neonate or infant patient, with the ability to also provide resuscitation therapy at a peak inspiratory pressure (PIP) as needed or desired without switching to another system or switching the patient interface. The system can include an expiratory pressure device capable of regulating a positive end expiration pressure (PEEP) of the system, which preferably can also induce pressure oscillations relative to a mean PEEP.

An apparatus for oxygenation and/or CO2 clearance of a patient. The apparatus comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow. The controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with at least two oscillating components. One oscillating component has a frequency based on the heart activity and/or trachea flow of the patient. One oscillating component has a frequency to: promote bulk gas flow movement, or promote mixing.

Ventilator enables operator to enter into the microprocessor estimate of a patient's individual characteristic, such as weight, which the microprocessor uses to control delivered tidal volume and other parameters to match the patient. The operator can select one of several ventilator operational modes (intube, mask, CPR). Sensors input data to the microprocessor to maintain parameter optimizations and accuracy. Visual/audible alarms and tools activate when one or more parameters exceed or fail to exceed predetermined values for patient's weight. Manual over-ride is available. The ventilator has a quick start capability in which the operator turns on power, selects the automatic operating mode, enters patient's characteristic, selects control option starting automatic ventilation of proper volumes inhalation/exhalation periods, pressure, and oxy-air mixture.

The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

An apparatus for delivery of a flow of gases to a user, such as a respiratory therapy apparatus, is provided. The apparatus may have first and second inlets for receiving supplementary gases flows, a blower to generate the gases flow to the user, and a controller. A valve and a sensor may be provided in the second inlet. The controller may be configured to detect the disconnection of a gases source from the second inlet, and to respond by operating the valve and/or triggering an alarm. The controller may be configured to determine whether a gases flow is being provided at one or both of the inlets, and to accordingly control an operational mode of the apparatus.

Embodiments of the present invention provide systems and methods for delivering respiratory treatment to a patient. For example, a treatment system may include a mechanism for delivering a positive pressure breath to a patient, and one or more limb flow control assemblies which modulate gas flow to and from the patient. Exemplary treatment techniques are embodied in anesthesia machines, mechanical ventilators, and manual ventilators.

High flow therapy is used to treat Cheyne-Stokes respiration and other types of periodic respiration disorders by periodic application of high flow therapy, adjustment of high flow therapy flow rates and/or periodic additions of CO2 or O2 into the air flow provided to the patient.

The disclosure relates to a method and respiratory system, comprising: a flow generator to provide a gas-flow to a patient, the gas flow comprising an oxygen fraction, and a controller configured to: receive input relating to oxygen fraction at a patient's nose and/or mouth, adjust the gas-flow flow rate based on the oxygen fraction at the patient's nose and/or mouth.

A ventilator system configured to switch between one or more invasive ventilation modes and one or more non-invasive ventilation modes is provided, the ventilator system comprising: an externally pressurized source of pre-mixed gas comprising air and oxygen; one or more inspiratory valves configured to deliver incoming pre-mixed gas to a patients breathing circuit; and one or more expiratory valves configured to remove outgoing gas from the patients breathing circuit; wherein in the one or more invasive ventilation modes, the inspiratory valves and the expiratory valves are configured to open and close to allow or prevent the passage of gas as needed in order to enforce a respiration cycle within the patient; and wherein in the one or more non-invasive ventilation modes, the inspiratory valves and the expiratory valves are kept open in order to allow the gas to pass freely through the system.

In a first embodiment, a ventilator has a housing with a first fixed port and a rotatable shutter configured to cooperate with the housing to enclose an interior of the housing. The shutter has a first orifice at a first radial distance from its axis of rotation. A stationary plate abuts the shutter and includes a first stationary orifice configured to at least partially align with the first orifice of the shutter over a first rotational distance of the shutter. In this way, the first orifice and the first stationary orifice form a first variable port. The stationary plate may have a second stationary orifice and the shutter may have a second orifice configured to at least partially align with the second stationary orifice over a second rotational distance of the shutter.