A device has a drainage conduit for draining fluids from a patient. The drainage conduit may be flexible. One or more flexible delivery conduits deliver medication to the patient. The one or more flexible delivery conduits are attached to the flexible drainage conduit. The one or more flexible delivery conduits are detachable from the flexible drainage conduits at at-least one end of the drainage conduit so that the delivery conduits can be peeled off the drainage conduit at the proximal and deployed with the proximal ends of the delivery conduits separated from the proximal end of the drainage conduit.

Clot removal from a patient's vessel, such as an artery, are described using aspiration and hydraulic forces supporting the removal process. Hydraulic forces can be generated by occluding the vessel distal to the clot and delivering liquid between the clot and the occlusive device. The aspiration catheter is positioned proximal to the clot. Catheters designed to facilitate the delivery of hydraulic forces can be based on single lumen designs or dual lumen designs. The catheters may have a fixed internal wire, or in some embodiments the catheters can ride over a wire with a valve/seal positioned to restrict flow into or out from the guide lumen such that the guide lumen can further function for balloon inflation and/or for infusion of liquid.

A medical device, for example a delivery catheter, may include a handle portion, a shaft portion extending distally from the handle portion, a deployment mechanism, and an actuation member positioned on the handle portion. The shaft portion may include a working channel and a distal tip portion having a payload chamber configured to receive a payload, such as a bio-absorbable foam. The distal tip portion may be operatively connected to the working channel. The deployment mechanism may be positioned in the working channel, and may be operable to deploy the payload out from the distal tip portion. The actuation member may be actuatable to operate the deployment mechanism.

A method of assisting a heart of a patient using a dual lumen cannula includes inserting the dual lumen cannula into the patient, positioning a first infusion tube of the dual lumen cannula in an artery near the heart to pump blood thereto, positioning a second drainage tube of the dual lumen cannula in a chamber of the heart to drain blood therefrom. The dual lumen cannula has a plurality of infusion apertures extending through a sidewall of the first infusion tube at a distal end of the first infusion tube; and a plurality of drainage apertures extending through a sidewall of the second drainage tube at a distal end of the second drainage tube. The distal end of the first infusion tube has a tapered portion extending distally beyond a distal-most infusion aperture of the plurality of infusion apertures and to a terminal surface at a tip of the first infusion tube.

A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site. A delivery machine may control the blood circuit and catheter assembly in order to both deliver perfusate to, and drain some or all perfusate from, the localized site in a manner that provides perfusate to substantially only the localized site.

The present invention relates to a sheath system that enables endovascular imaging and treatment of concomitant multiple lesions, both in antegrade and retrograde direction in a blood vessel. Further, the present invention relates to a method for using the sheath system enabling endovascular imaging and treatment of concomitant multiple lesions, both in antegrade and retrograde direction.

A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site. A delivery machine may control the blood circuit and catheter assembly in order to both deliver perfusate to, and drain some or all perfusate from, the localized site in a manner that provides perfusate to substantially only the localized site.

A catheter for insertion into a body of a patient, and methods of making and using. The catheter can include a distal portion that remains stable during fluid infusion into the patient, thus reducing or eliminating whipping of the catheter distal tip. The catheter can include a proximal portion including a first cross sectional lumen area; a distal portion including a second cross sectional lumen area larger than the first cross sectional lumen area such that the distal portion prevents whipping when the catheter is disposed in a patient and a fluid exits the catheter. The catheter can be attached to a vascular access port and a method can include power injecting a fluid through the vascular access port and the catheter.

The present disclosure relates to a hemodialysis catheter that can monitor intravascular pressure using a MEMS sensor. The hemodialysis catheter comprises a venous lumen, an atrial lumen, and at least one MEMS system sensor. The hemodialysis catheter also comprises a data acquisition and processing system. The hemodialysis catheter can communicate with a monitor system to display pressure data.

A single or multiple lumen catheter is disclosed which includes an expandable lumen. The expandable lumen is movable from a collapsed or sealed configuration to an open or expanded configuration. In the open configuration, the expandable lumen is dimensioned to receive a guidewire or stylet or facilitate the introduction of fluids into a patient.