A medical manifold for use in providing access to a fluid flow path. The medical manifold can include a valve member having a diaphragm and first and second support members extending from a bottom surface of the diaphragm. The first and second support members can be positioned to define a line of symmetry that's bisects the bottom surface of the diaphragm. The diaphragm can have a first position in which a top surface thereof is generally planar and a second position in which the diaphragm is flexed downward around the line of symmetry.

Disposable set for an extracorporeal blood treatment system. The disposable set includes an extracorporeal blood circuit having a blood withdrawal line and a blood return line configured to be attached to a blood treatment device and an infusion circuit coupled to the extracorporeal blood circuit through infusion lines. The disposable set further includes an infusion valve unit configured to be releasably connected to an infusion pump of the extracorporeal blood treatment system, the infusion valve unit incorporating a one-way valve or seal to control the flow of infusion liquid through the infusion cicuit.

A check valve includes an upper housing defining an inlet of the check valve, a lower housing defining an outlet of the check valve, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve further includes a valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. The valve member includes a valve body and a valve stem portion extending axially through a central axis of the valve body.

A connector-with-integrated-check-valve for minimizing microbial migration to catheter-tubing is formed from three parts: a connector-for-catheter-tubing that is hollow and with an internal valve seat; an elastomer gate (sometimes with disc and stem); and a connector-for-extension-tubing that is hollow and with support-surfaces. When one end of the connector-for-catheter-tubing is attached to one end of the connector-for-extension-tubing, a pocket is formed where the seat is disposed opposite and facing the support-surfaces; the gate is disposed within this pocket; such that when the gate contacts this seat due to urine backflow (reflux), the connector-with-integrated-check-valve is closed to such urine backflow; and where a remaining end of the connector-for-catheter-tubing is attachable to catheter-tubing; and where a remaining end of the connector-for-extension-tubing is attachable to the extension-tubing, such that there is a continuous urine flow path from the catheter-tubing, to the connector-with-integrated-check-valve when open, and to the extension-tubing.

In one aspect, fluid flow control systems, such as for medical applications, may include a resistance barrier and a flexible ring that may receive a device. The resistance barrier may exert barrier forces on the device, and the flexible ring may exert ring forces on the device, in order to create a fluid tight seal.

A method for protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism is disclosed. The method includes associating the pressure transducer with an isolation port of the pressure isolation mechanism, placing a pressurizing device for delivering fluid under pressure in fluid connection with an inlet port of the pressure isolation mechanism, and actuating the pressurizing device to cause fluid flow in the inlet port such that a free floating, fluid flow responsive valve member positioned in an internal cavity of the pressure isolation mechanism engages a seal seat therein to attain a closed position, preventing fluid flow between the inlet port and the isolation port and thus prevent overpressure in the isolation port. Hemodynamic pressure signals read with the pressure transducer may be transmitted at least in part through a body of the valve member, or a portion thereof, when in the closed position.

A check valve assembly is configured to couple to a first container that retains a first fluid and a second container that retains a second fluid. The check valve includes a fluid inlet housing including a first fluid inlet port defining a first fluid inlet channel, and a second fluid inlet port defining a second fluid inlet channel. A fluid outlet housing is coupled to the fluid inlet housing. The fluid outlet housing includes a fluid outlet port defining a fluid outlet channel. A first diaphragm is seated over the first fluid inlet channel. At least a portion of the first diaphragm is configured to unseat over the first fluid inlet channel to allow the first fluid to pass from the first fluid inlet channel into the fluid outlet channel. A second diaphragm is seated over the second fluid inlet channel. At least a portion of the second diaphragm is configured to unseat over the first fluid inlet channel to allow the second fluid to pass from the second fluid inlet channel into the fluid outlet channel.

Disclosed herein are devices and methods related to UV disinfection of a transfer catheter during peritoneal dialysis. The transfer catheter comprises a first and second end, the second end comprising a transfer valve. The transfer valve body comprises an inlet, outlet, and a flush hole. The valve core comprises a notch configured to allow fluid flow between the various flow paths. The valve core and body are positioned off axis with respect to the fluid flow path. The transfer catheter can allow for a small volume kill zone, which can minimize the amount of UV required to disinfect the catheter.

A male reflux valve comprising a distal body portion and a proximal body portion, the proximal body portion having a male connection for connection to a female connection of an access device, a valve element operatively positioned within the distal body portion, a core operatively positioned within the distal body portion to retain the valve element into sealing engagement with the distal body portion and an actuator reciprocably retained within a generally circular cylindrical longitudinal bore of the proximal body portion in engagement with the valve element to open the valve element when engaged by the female connection of the access device.

The fluid delivery system includes a pressurizing device for delivering a pressurized injection fluid, a low pressure fluid delivery system, and a pressure isolation mechanism adapted for fluid communication with the pressurizing device and low pressure fluid delivery system. The pressure isolation mechanism includes a housing defining an inlet port, an isolation port, and an internal cavity. The housing defines a seal seat in the internal cavity between the inlet port and isolation port. A valve member is disposed in the internal cavity. The valve member is free floating in the internal cavity and is adapted to engage the seal seat. The valve member has an open position permitting fluid communication between the inlet port and isolation port, and is fluid flow responsive to fluid flow in the inlet port to engage the seal seat and attain a closed position preventing fluid flow between the inlet port and isolation port.