A method for beam therapy is provided. The method includes receiving first data indicating a plurality of target volumes within a target region inside a subject for particle beam therapy relative to a particle beam outlet on a gantry for directing a particle beam from a particle beam source. The method further includes moving automatically, one or more energy modulator components to reduce an energy of the particle beam and deliver the particle beam to the target region such that a Bragg Peak is delivered to at least one target volume of the plurality of target volumes. The method further includes repeating the moving automatically as the particle beam source rotates with the gantry around the subject, without changing the energy of the particle beam at the particle beam outlet, until every target volume is subjected to a Bragg Peak.

Described herein is a system and method of controlling real-time image-guided adaptive radiation treatment of at least a portion of a region of a patient. The computer-implemented method comprises obtaining a plurality of real-time image data corresponding to 2-dimensional (2D) magnetic resonance imaging (MRI) images including at least a portion of the region, performing 2D motion field estimation on the plurality of image data, approximating a 3-dimensional (3D) motion field estimation, including applying a conversion model to the 2D motion field estimation, determining at least one real-time change of at least a portion of the region based on the approximated 3D motion field estimation, and controlling the treatment of at least a portion of the region using the determined at least one change.

A patient supporting device includes: a base; a positioner; a platform having a first end and a second end; and a controller; wherein the positioner is operable by the controller to place the platform at one of a first plurality of possible positions or at one of a second plurality of possible positions, wherein in any of the first plurality of possible positions, the second end of the platform is closer to one of a left side and a right side of a treatment machine; wherein in any of the second plurality of possible positions, the second end of the platform is closer to another one of the left side and the right side; and wherein a size of a first spatial region defined by the first plurality of possible positions is different from a size of a second spatial region defined by the second plurality of possible positions.

The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.

A radiation device directs a beam of radiation onto a target. The beam can be adjusted using, for example, a control for setting beam shape and a control for setting beam intensity. The target is supported on a surface that can be adjusted using, for example, a control for setting surface position and a control for setting a speed for moving the surface. Controls are selected to adjust the beam and the surface cooperatively in order to compensate for movement of the target.

A computer-implemented method for a radiation therapy system includes: acquiring a first X-ray image of a region while the region is in a first location, the gantry is in a first imaging position, and a center axis of an imaging beam passes through an isocenter of the radiation therapy system along a first imaging path; acquiring a second X-ray image of the region while the region of patient anatomy is in the first location, the gantry is in a second imaging position, and the center axis of the imaging beam passes through the isocenter along a second imaging path, wherein an angle between the first imaging path and the second imaging path is a non-orthogonal angle; and based on the first X-ray image, the second X-ray image, and a three-dimensional treatment planning image of the region, determining an offset between a planning location for the region and the first location.

According to some embodiments, an image processor includes an image generator, a region acquirer, and a label applicator. The region acquirer acquires at least one two-dimensional region designated on at least one first perspective image generated from three-dimensional volume data of a target. The label applicator applies a label on at least one first three-dimensional region. The at least one first three-dimensional region is a part of a second three-dimensional region. The second three-dimensional region is defined by the at least one two-dimensional region, a point and a surface which is defined by a set of straight lines between the point and the boundary of the two-dimensional region. The first three-dimensional region is defined to be a first overlapping region where the three-dimensional volume data and the second three-dimensional region overlap.

A medical image processing device of an embodiment includes a first image acquirer, a second image acquirer, a generator, and a calculator. The first image acquirer acquires a first fluoroscopic image of a patient. The second image acquirer acquires a second fluoroscopic image according to radiation with which the patient is irradiated at a time point different from a time point of acquisition of the first fluoroscopic image from a photography device that detects radiation with a detector and performs an imaging process. The generator generates a reconstructed image obtained by reproducing the second fluoroscopic image from the first fluoroscopic image virtually arranged in a three-dimensional space on the basis of an installation position of the detector in the three-dimensional space. The calculator obtains a suitable position on the first fluoroscopic image in the three-dimensional space on the basis of a degree of similarity between the second fluoroscopic image and the reconstructed image. The generator generates the reconstructed image which is for use in the calculator and has a range larger than a range corresponding to the second fluoroscopic image.

In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.

A more accurate radiotherapy is implemented by using a vessel marker for radiotherapy having a deformation fixed shape for engaging with the inner wall of a vessel by deformation after being inserted into the vessel, and a position notification shape for notifying an outside of a radiation irradiation position. Also provided are a radiotherapy support method for supporting radiotherapy to be performed by using the vessel marker, a radiation irradiation control apparatus that irradiates, with radiation, a patient in which the vessel marker is indwelled, and a vessel marker indwelling support apparatus to be used when indwelling the vessel marker.