Threaded sacro-iliac joint stabilization (e.g., fusion, fixation) implants and methods of implantation and manufacture. Some implants include a threaded distal region, an optionally threaded central region, and an optionally threaded proximal region. The distal, central, and proximal regions have lengths such that when the implant is laterally implanted across a SI joint, the distal region can be positioned in a sacrum, the central region can be positioned across an SI-joint, and the proximal region can be positioned in an ilium.

The present invention provides a deformable body (2), wherein the deformable body comprises a force application surface (12) opposite a bone contact surface (52) to be pressed against periosteum of a bone surface (52) of a bone such that the bone contact surface adapts its shape to the shape of the bone surface, wherein the deformable body comprises one or more through-going openings (3) and/or one or more fixation locations (34) arranged to receive a fixation element such as as screw (20), and wherein the deformable body comprises an anaesthetic that is released from or through the bone contact surface. The anaesthetic can be bupivicaine, liposome bupivacaine, lidocaine or levobupivacaine. The anaestethic can be arranged in one or more compartments (6, 7) which have ifferent release rates. The screw can comprise a detent or rim to mate with the deformable body. A sleeve (80) can be arranged in the opening (3) to receive the screw. A pusher element (81) can push the deformable body from the sleeve into position on the screw.

Bone graft scaffold arrangements are described that can be used in minimally invasive posterolateral spinal fusion. The bone graft scaffold apparatus comprise a housing which comprises a cavity for receiving bone growth promoting materials and a plurality of apertures. In use these allow bone and blood vessels to grow through the plurality of apertures to form the bone bridge between vertebrae. Further the bone graft scaffold apparatus comprise at least one opening in the housing for receiving a shaft of an orthopaedic device, such as rod linking pedicle screws, or the shaft of a pedicle screw, or another suitable shaft in another surgical procedure. The apparatus can be attached to structural components such as rods and screws and used to form a continuous scaffold between vertebras to assist in forming a bone bridge.

An implant for fusing a joint between first and second bone portions. The implant includes a screw member, and a washer polyaxially rotatable relative to the screw member. The screw member includes a head, a lag zone, and a threaded engagement zone. The implant includes a fusion zone for joint compression, extending from the washer to the proximal end of the engagement zone. Fenestrations may be present in the fusion zone. The length of the fusion zone ranges from about 10 mm to about 37 mm. Different surface finishes including roughened and non-roughened may be applied selectively to selected portions of the implant. In an embodiment, the joint is a sacro-iliac joint, and upon implantation the implant extends from the exterior of the ilium, across the joint and into the sacral vertebral body. Instrumentation and methods for preparing the joint and implanting the implant are disclosed.

Apparatus and methods for delivery of an implant at a target site in an interior of a bone. The apparatus may include a plate. The plate may include a bottom surface complementing a surface contour of a bone. The plate may define first holes sized for receiving screws. The plate may define second holes sized for receiving fixation elements. The plate may define an opening. The opening may be sized for providing passage of the implant through the plate. When the bottom surface is seated complementarily against the surface contour, the first holes may point into an interior of the bone and into a volume occupied by the implant in the interior when the implant is positioned at a target site and radially expanded to form a mesh cage.

A tissue fixation implant that includes leading fixation and trailing fixation members, each fixation member having a proximal head and an elongate shank with a distal tip, and each fixation member adapted to at least partially contact the other fixation member at one or more points along their respective lengths. The tissue fixation implant includes a proximal inter-engagement feature for fixedly engaging each of the two fixation members relative to one another when engaged within tissue, including bone tissue, soft tissue, and combinations of these, and has an interior chamber suitable for receiving osteogenic material to enhance new bone growth and fusion of the fixation implant within bone.

A bone anchor locking device for receiving a bone anchor having a shank and an enlarged head, the device has a bone anchor, a dome and a conical split washer. The receiving portion has a base extending radially outward and inwardly to a wall. The dome has a center aperture sized to pass a bone anchor. The split washer has an inner conical surface sloped to slide and expand against at least a portion of the base on insertion of a bone anchor to allow a maximum diameter of a head of a bone anchor to pass and thereafter the split washer retracts overlying the maximum diameter of the head to prevent a bone anchor from backing out.

The invention provides a hydrogel for in-vivo release of medication comprising at least one medication, wherein the surface of the hydrogel comprises a coating such that the surface has one or more sub-surfaces with permeability that is at least 2× higher than the average permeability of the entire surface, wherein the hydrogel has an elastic modulus of between 50 and 1000 kPa.

An intramedullary nail implant for positioning in a bone having a head and a shaft defining an intramedullary canal. The implant includes a distal portion having a shaft extending along a central axis and configured for positioning within the intramedullary canal. A proximal portion extends proximally from the distal portion. The proximal portion defines a contact surface which extends at least in part medially of the central axis such that it is configured to extend within a medial portion of the bone head. A method of implanting the nail is also provided.

Orthopedic implants capable of compressing adjacent bone segments into which they are inserted, effective for the fusion, management and repair of bone joints and bone fractures, and methods for their installation, are described. One embodiment of such implants includes an elongated shaft coated to encourage bony in-growth, having a non-round cross section, and a flange at one end, which is laterally inserted into a preformed insertion path formed in adjacent bone segments traversing a joint or fracture location, to the point where further insertion is blocked by the flange intersecting one of the bone segments. The other end of the shaft may have a portion of male thread protruding out of the insertion path in the second of the bone fragments and adapted to be mated to a fastener having female thread. When the fastener is tightened against the outside of the second bone segment, perhaps using a washer, the joint or fracture is compressed and stabilized resulting in an effective fusion of the joint or fracture when the bone secures itself in the insertion path to the shaft's bony in-growth surfaces on both sides of the joint or fracture line.