A storage and mixing device for PMMA bone cements having a cylindrical interior of the cartridge that is delimited on a front side by a cartridge head with a closed delivery opening, a plunger which is arranged to be axially movable in the cylindrical interior of the cartridge and which is spaced from the cartridge head. The plunger circumferentially rests against the inner wall of the interior, so that the plunger divides the interior of the cartridge into two sections in a gas-tight manner, a powdery first parent component of the bone cement, which is contained in the interior between the plunger and the cartridge head, a feed-through which is arranged in the cartridge head or in the cylinder barrel of the cartridge between the plunger and the cartridge head, wherein the feed-through is connected to a fluid line in which a monomer liquid as a second parent component of the bone cement is contained or into which a monomer liquid is fillable or introducible. A filter is arrangeable in the cartridge head, in the feed-through and/or in the fluid line, wherein the filter is permeable to the monomer liquid and impermeable to the first parent component, wherein the plunger is spaced from a back side of the cylindrical interior, located opposite the front side, to an extent that, by moving the plunger in the direction of the back side, a reduced pressure is producible in the interior of the cartridge between the plunger and the cartridge head, wherein the reduced pressure is able to suck the monomer liquid out of the fluid line into the interior of the cartridge.

The present invention provides a negative pressure guided bone cement injection systme comprising a negative pressure system, comprising a negative pressure introduction device, a pushing system for implant bone cement to the target area, a control systmem for regulating the negative pressure system and the pushing system, and at least one sensing device disposed at any position of the negative pressure system, which can sense at least one environmental paramtere for observing the physiological condition of a patient's spinal vertebral body can be monitored immediately, and the result is actively or passively sent back to the system or the operator for adjusting the injection parameters.

A handle connectable to a screw-type mechanical drive component for transmitting to the latter a first torque comprises first connection means, defining a constraint axis, for the connection of the handle to the mechanical drive component, a ring nut to which a second torque is manually applicable, support means of the ring nut for rotatably supporting the latter around an axis of rotation coinciding, in use, with the constraint axis, second means for connecting the ring nut to the support means, for connecting/disconnecting the ring nut and the support means in a mechanical and selective way, so that the ring nut is kinematically connected to the support means when rotated around the axis of rotation with a second torque lower than a threshold value and kinematically disconnected from the same upon exceeding such a threshold value.

A filter assembly for a surgical suction system. The filter assembly has a containment defining a filter chamber an intake fitting on an upstream end of the chamber, an output fitting on an opposite downstream end of the chamber, and a filter element in the filter chamber and made at least partially of a bioresorbable bone substitute so that autologous tissue components carried in a fluid flowing from the fitting through the filter element in the filter chamber are trapped by the filter element.

Inflatable medical devices and methods for making and using the same are disclosed. The inflatable medical devices can be medical balloons. The balloons can be configured to have a through-lumen or no through-lumen and a wide variety of geometries. The device can have a high-strength, non-compliant, fiber-reinforced, multi-layered wall. The inflatable medical device can be used for angioplasty, kyphoplasty, percutaneous aortic valve replacement, or other procedures described herein.

One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder and for delivering the bone cement paste, the device having a cartridge with a cylindrical interior, the interior of the cartridge being closed at the front side apart from a delivery opening for discharging the bone cement paste from the interior. A delivery plunger is arranged in the interior of the cartridge and mounted so as to be pushable in the direction of the delivery opening. The cement powder is arranged in the interior of the cartridge between the delivery opening and the delivery plunger. A closure closes the delivery opening and is mounted so as to be movable relative to the delivery opening. A line element is arranged at the front side of the delivery opening and includes a closure receptacle for receiving at least part of the closure. The closure is pushable into the closure receptacle by pressure on the bone cement paste such that the delivery opening is opened, when the closure has been pushed into the closure receptacle, the line element provides a free line cross-section through which the bone cement paste is pushable out through the delivery opening and out of the device.

One aspect relates to a device to produce a bone cement paste from a monomer liquid and a cement powder as starting components of the bone cement paste, and to dispense the mixed bone cement paste. The device includes a cartridge with a cylindrical interior, a dispensing plunger movable towards the front of the cartridge; a receptacle extending along a longitudinal direction, a front of the receptacle connected with the rear of the cartridge; a pumping plunger arranged and in the receptacle movable towards the front of the receptacle; a breakable ampoule containing the monomer liquid, the ampoule with ampoule body arranged in the receptacle between the pumping plunger and the dispensing plunger with at least some sections of the ampoule body in contact with the receptacle; and a spacer arranged in the receptacle between the dispensing plunger and the ampoule body, the spacer extending in the longitudinal direction of the receptacle and the spacer being separated from the inner wall of the receptacle by a distance at least as large as the wall thickness of the ampoule body.

One aspect relates to a bone cement applicator having a cartridge with an interior, a cartridge head with a delivery opening, a mixing member which is movable in the interior with a mixing rod. A delivery plunger is arranged in the cartridge and is mounted in the interior and is pressable in the direction of the delivery opening. The delivery plunger rests with an outer cylindrical circumferential surface against an inner wall of the cartridge. A clamping element is arranged on the inner wall of the cartridge in the region of a back side of the interior. The clamping element projects out of the inner wall of the cartridge. The cylindrical circumferential surface of the delivery plunger is resiliently deformable by the clamping element in the direction of a central cylinder axis, such that the delivery plunger is clampable in place with the at least one clamping element on the back side of the cartridge.

Devices used to pressurize, depressurize, or otherwise displace fluid are disclosed. The devices may be configured as a syringe. The syringe may be configured to generate high-pressure within the syringe to inflate or deflate a medical device, such as a balloon, or to inject a substance, such as bone cement, into a bone, such as a vertebra. The syringe may include a pressure reduction mechanism used to depressurize the syringe.

An inflatable bone tamp includes an outer shaft defining a passageway. An inner shaft is positioned within the passageway. The inner shaft defines a lumen. A balloon has a first end coupled to the outer shaft and a second end coupled to the inner shaft such that material can flow through the lumen and into the balloon and exit the balloon through a channel between the inner and outer shafts. A valve is positioned within the channel. The valve is configured to move from a closed orientation in which the valve blocks the channel and an open orientation in which the does not block the channel. Kits, systems and methods are disclosed.