The present invention refers to an intraocular lens provided with specific diffractive profile, in which each step height is individually defined, with no fixed pattern. The intraocular lens provides a better control of the luminous efficiency of each focal point, guaranteeing more flexibility and customization, being adaptable to the optical quality that the patient needs.

Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable accommodating intraocular lens comprises an optic portion and at least one haptic. At least part of the haptic can be made in part of a composite material comprising an energy absorbing constituent and a plurality of shrinkable and/or burstable microspheres. At least one of a base power of the optic portion can be configured to change in response to an external energy directed at the composite material.

Devices and methods for novel retinal irradiance distribution modification (IDM) to improve, stabilize or restore vision are described herein. Also encompassed herein are devices and methods to reduce vision loss from diseases, injuries and disorders that involve damaged and/or dysfunctional and/or sensorily deprived retinal cells. Conditions that may be treated using devices and methods described herein include macular degeneration, diabetic retinopathy and glaucoma. Therapy provided by retinal IDM devices and methods described herein may also be used in combination with other therapies including, but not limited to, pharmacological, retinal laser, gene and stem cell therapies.

An accommodation-facilitating intraocular implant has: a ring sized to fit within a capsular lens bag of an eye; and a plurality of haptics angularly spaced around and radially extended from the ring. A multi-curve implantable accommodating intraocular lens has a convex anterior and concave posterior.

Hybrid Accommodating Intra Ocular Lens (AIOL) assemblages including two discrete component parts in the form of a discrete base member for initial implantation in a vacated capsular bag and a discrete lens unit for subsequent implantation in the vacated capsular bag for anchoring to the discrete base member. The lens unit includes a lens optics having at least two segmented lens haptics radially outwardly extending therefrom.

Method to design manufacture an intraocular lens, comprising an optical part and haptics part, in which the optical part comprises an anterior surface with negative refractive power and a posterior surface with positive refractive power, in which in order to determine the refractive power D of the anterior surface of the optical part and the refractive power D′ of the posterior surface of the optical part the following steps are performed: a plurality of light rays are provided over the normal eye, both on the optical axis (1001) and forming different angles (714, 715, 716) with respect to the optical axis (1001), for each light ray with its angle the axial length of the eye and the refractive power of the cornea are measured, determination of the shape of the retina (200) through a mathematical fit to an aspherical surface that contains the measured points, calculation of the arc length S that goes from the intersection of the optical axis with the retina (200) of the eye to the intersection of the light ray with the retina (200) of the eye for each angle, as a function of the shape of the retina (200) and the angle of the light ray, fit of the refractive power D of the anterior surface of the optical part and refractive power D′ of the posterior surface of the optical part using ray tracing optimization in a pseudophakic eye model.

A substrate carries electrical components. It is bent into a non-planar shape to fit into a contact lens. For example, the substrate may be constructed from a flexible circuit board. The circuit board has certain regions for mounting electrical components. The flexible circuit board is bent into a three-dimensional shape that fits into the contact lens. The regions used to mount electrical components remain flat.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes applying a plurality of laser pulses to the IOL. The laser pulses can be configured to produce, by refractive index writing on the IOL, a predetermined change in phase profile of the IOL to increase spectacle independence.

A transmissive ophthalmic lens has a first surface opposite a second surface. The first surface includes a centrally disposed diffractive multifocal zone surrounded by a peripherally disposed refractive non-multifocal zone. The second surface is a refractive non-multifocal surface. The refractive non-multifocal zone forms the far focus. The diffractive multifocal zone is no more than 2.5 millimeters in diameter to produce a far focus and an Add focus and no less than 1.5 mm in diameter for Multipeak performance. A first groove and a second groove of the diffractive multifocal zone may be the only two grooves. At least 20% of light is directed within the diffractive multifocal zone to one of the far and the Add focus. The diffractive multifocal zone may have a base curve that together with a peripheral zone is bi-sign aspheric around far focus and aspheric grooves configured for minimum spherical aberration at the Add focus.

Method to design manufacture an intraocular lens, comprising an optical part and haptics part, in which the optical part comprises an anterior surface with negative refractive power and a posterior surface with positive refractive power, in which in order to determine the refractive power D of the anterior surface of the optical part and the refractive power D′ of the posterior surface of the optical part the following steps are performed: a plurality of light rays are provided over the normal eye, both on the optical axis (1001) and forming different angles (714, 715, 716) with respect to the optical axis (1001), for each light ray with its angle the axial length of the eye and the refractive power of the cornea are measured, determination of the shape of the retina (200) through a mathematical fit to an aspherical surface that contains the measured points, calculation of the arc length S that goes from the intersection of the optical axis with the retina (200) of the eye to the intersection of the light ray with the retina (200) of the eye for each angle, as a function of the shape of the retina (200) and the angle of the light ray, fit of the refractive power D of the anterior surface of the optical part and refractive power D′ of the posterior surface of the optical part using ray tracing optimization in a pseudophakic eye model.