A slit lamp and biomicroscope assembly can include a viewing system including a biomicroscope; an illumination system including a slit lamp with a light source and a light processing system with a first actuator; a positioning system supporting the biomicroscope and the slit lamp and including second and third actuators to position the biomicroscope along horizontal and vertical axes; and a user interface handle. The user interface handle can be graspable by a hand of a user and supported on the positioning system proximate to the biomicroscope such that a user looking into the biomicroscope can reach the user interface handle. The user interface handle can include a plurality of input devices including input devices in communication with the actuators.

An accommodating intraocular lens assembly can include a first lens, a first stanchion, a second lens, and a second stanchion. The first lens can have a first anterior side and a first posterior side. The first stanchion can have a first distal end connected to the first lens and a first base end. The second lens can have a second anterior side and a second posterior side. The second stanchion can have a second distal end connected to the second lens and a second base end. The first lens and the second lens can move laterally relative to one another during contraction of the ciliary muscle in a vertically-extending plane containing the optic axis of the eye and substantially centered in the eye.

A trephination apparatus can include a first member, a blade, and a second member. The first member can include a through-aperture and a first internal chamber. The first member can also include opening to the first internal chamber that can surround the through-aperture in a plane. The blade can have an outwardly-facing male profile at least partially matching the through-aperture and have a cutting edge. The second member can include a first body sized to be received in the through-aperture with the blade. The blade can be positionable between the first body and the female profile at the second opening. The second member can also include a second internal chamber with an opening extending about the aperture axis in the plane with an opening to the first internal chamber.

Exemplary light control devices and methods provide a regional variation of visual information and sampling (V-VIS) of an ocular field of view that improves or stabilizes vision, ameliorates a visual symptom, reduces the rate of vision loss, or reduces the progression of an ophthalmic or neurologic condition, disease, injury or disorder. The V-VIS devices and methods generate a moving aperture effect anterior to a retina that samples and delivers to the retina environmental light from an ocular field of view at a sampling rate between 50 hertz and 50 kilohertz. Certain of these V-VIS devices and methods may be combined with augmented or virtual reality, vision measurement, vision monitoring, or other therapies including, but not limited to, pharmacological, gene, retinal replacement and stem cell therapies.

The present disclosure provides an intralocular-lens (IOL) or ophthalmic device including an optic and at least one haptic, at least a portion of which is formed from a photoresponsive shape memory polymer network, such as a polydomain azo liquid crystalline polymer network (PD-LCN). The present disclosure further provides systems and methods for adjusting the position of such an IOL or other ophthalmic device using polarized laser radiation.

Exemplary light control devices and methods provide a regional variation of visual information and sampling (V-VIS) of an ocular field of view that improves or stabilizes vision, ameliorates a visual symptom, reduces the rate of vision loss, or reduces the progression of an ophthalmic or neurologic condition, disease, injury or disorder. The V-VIS devices and methods generate a moving aperture effect anterior to a retina that samples and delivers to the retina environmental light from an ocular field of view at a sampling rate between 50 hertz and 50 kilohertz. Certain of these V-VIS devices and methods may be combined with augmented or virtual reality, vision measurement, vision monitoring, or other therapies including, but not limited to, pharmacological, gene, retinal replacement and stem cell therapies.

Lens support structure for supporting an intraocular lens (IOL) is provided, the lens support structure being configured and operable to be securely implanted in a lens capsule of a human eye and hold the IOL in one of a plurality of positions, the support structure comprising a repositioning assembly configured and operable to be activated remotely by a remote energy source and controllably displace the IOL in at least one of directions along and around an optical axis of the IOL, thereby enabling moving the IOL between the plurality of positions. Lens control system is also provided, the control system comprising the lens support structure and a source energy for activating parts thereof. Intraocular lens system is also provided, the system comprising the lens support structure and a lens integrated therein.

Exemplary light control devices and methods provide a regional variation of visual information and sampling (V-VIS) of an ocular field of view that improves or stabilizes vision, ameliorates a visual symptom, reduces the rate of vision loss, or reduces the progression of an ophthalmic or neurologic condition, disease, injury or disorder. The V-VIS devices and methods generate a moving aperture effect anterior to a retina that samples and delivers to the retina environmental light from an ocular field of view at a sampling rate between 50 hertz and 50 kilohertz. Certain of these V-VIS devices and methods may be combined with augmented or virtual reality, vision measurement, vision monitoring, or other therapies including, but not limited to, pharmacological, gene, retinal replacement and stem cell therapies.

A multi-piece IOL assembly is provided that includes a platform and an optic. The platform has an inner periphery surrounding an inner zone of the platform. The optic has an optical zone, an outer periphery and a retention mechanism disposed on the outer periphery. The optic is configured to be disposed in the inner zone of the platform and to extend to a location between the inner periphery and the outer periphery of the platform to be secured to the platform at the location. The platform can be secured to an inner periphery of the eye or can be formed into a natural lens by cutting the lens using a laser or other energy source.

Accommodating intraocular lens including a combination of variable lenses. Firstly, a variable lens including two spherical lenses fitted onto two optical elements to provide variable optical power of which the degree depends on the degree of movement of at least one of spherical lens along the optical axis. Secondly, a variable lens comprising at least two cubic surfaces fitted onto the same two optical elements which provides a lens of variable optical power of which the degree depends on the degree of movement of at least one of the optical elements in a direction perpendicular to the optical axis. The combination of variable lenses is fitted into a mechanical construction providing said movements of the optical elements.