Ionized radiation-absorbed, dose sensitive, highly flexible polymeric compositions are provided that exhibits multidirectional changes in refractive index. Also provided are methods of producing a precision multi-directional nanogradient of refractive index in a polymeric composition.

An intraocular lens comprises a lens body customized for astigmatism in a particular eye. For the customization to work, the astigmatism in the lens has to be aligned with astigmatism in the eye. Thus the intraocular lens comprises four protrusions arranged outwardly around the lens body to form the four corners of a substantially rectangular profile. The profile locks the intraocular lens into a position of rotational stability when inserted into a capsular bag, thus preventing rotation of the intraocular lens, which would otherwise tend to occur both immediately after insertion into the capsular bag and later on during growth, shrinkage or other change to the capsular bag. The Intraocular lens may additionally be customized for other eye conditions and a multi-focal embodiment is also disclosed.

A multicomponent intraocular lens implantable in an optical system of a human eye, comprising: a base component and a front component, the front component comprising an attachment tab which extends from a circumferential side of the optical portion of the front component and engages the flange for attaching the front component to the base component, wherein the attachment tab of the front component comprises a resilient projection that protrudes away from the optical portion beyond the flange, wherein a portion of the resilient projection is located at a non-overlapping position with respect to the haptic of the base component in a circumferential direction around the optical portions, wherein the portion of the resilient projection has a back surface which is located backwards from a front surface of the haptic of the base component in the thickness direction of the base component.

Multifocal intraocular lens with extended depth of field that comprises, in at least one of the surfaces (2), a small zone with a multifocal profile with a defined optical axis (3) and, in the peripheral region and coaxial to the multifocal zone, a ring-shaped opaque mask (1) that partially or totally block light to produce a small aperture effect and, therefore, the multifocal profile has a radius equal or larger than the internal radius of the mask (1), and there is at least one transition between focal zones or one diffractive step inside the internal radius of the mask (1).

The embodiments disclosed herein include improved toric lenses and other ophthalmic apparatuses (including, for example, contact lens, intraocular lenses (IOLs), and the like) and associated method for their design and use. In an embodiment, an ophthalmic apparatus (e.g., a toric lens) includes one or more angularly-varying phase members comprising a diffractive or refractive structure, each varying the depths of focus of the apparatus so as to provide an extended tolerance to misalignment of the apparatus when implanted in an eye. That is, the ophthalmic apparatus establishes an extended band of operational meridian over the intended correction meridian.

The embodiments disclosed herein include improved toric lenses and other ophthalmic apparatuses (including, for example, contact lens, intraocular lenses (IOLs), and the like) that includes one or more refractive angularly-varying phase members, each varying depths of focus of the apparatus so as to provide an extended tolerance to misalignments of the apparatus. Each refractive angularly-varying phase member has a center at a first meridian (e.g., the intended correction meridian) that directs light to a first point of focus (e.g., at the retina of the eye). At angular positions nearby to the first meridian, the refractive angularly-varying phase member directs light to points of focus of varying depths and nearby to the first point of focus such that rotational offsets of the multi-zonal lens body from the center of the first meridian directs light from the nearby points of focus to the first point of focus.

Ionized radiation-absorbed, dose sensitive, highly flexible polymeric compositions are provided that exhibits multidirectional changes in refractive index. Also provided are methods of producing a precision multi-directional nanogradient of refractive index in a polymeric composition.

An intraocular lens (IOL) with a shape-changing optic is provided. The shape-changing optic includes an elastic anterior face located anterior to the equator. The anterior face has an anterior surface, a posterior surface, and a periphery. The shape-changing optic also includes a posterior face having an anterior surface, a posterior surface, and a periphery. An elastic side wall can extend across the equator and extend from the anterior face to the posterior face. A chamber can be located between the anterior face and the posterior face. The IOL can further include at least one haptic extending from the periphery of the anterior face, the periphery of the posterior face, or both.

The disclosure provides a method for selecting toric intraocular lenses (IOL) and relaxing incision for correcting refractive error. The one or more toric IOL and relaxing incision combinations can be used for off-axis correction of refractive errors such as astigmatism. The disclosure provides a method for selecting toric IOL and relaxing incision combinations that have combined astigmatism correcting powers and off-axis positions or orientations of the astigmatism correcting axes of the toric IOL and relaxing incision that are effective to yield lower residual astigmatism than on axis correction methods. The toric IOL and relaxing incision combinations also allow the user to avoid incisions that will radially overlap with a cataract incision thereby provided improved outcomes.

Provided is an intraocular lens including a lens body having a back surface disposed on a retinal side and a front surface disposed on a corneal side, wherein an entire back surface is shaped in such a way as to protrude from a peripheral edge of the back surface toward the retinal side in a direction of an optical axis, in a shape of a truncated cone, and the front surface has any of the following shapes (i) to (iii); (i) the front surface is shaped in such a way as to start to be recessed toward the retinal side in the direction of the optical axis when viewed toward a center from a peripheral edge of the front surface, (ii) the front surface is shaped in such a way that an initial part from the peripheral edge of the front surface toward the center is flat, (iii) the front surface is shaped in such a way as to start to protrude toward the corneal side in the direction of the optical axis when viewed toward the center from the peripheral edge of the front surface, but a rate of rise of a protrusion from the peripheral edge of the front surface is smaller than a rate of rise of a protrusion from the peripheral edge of the back surface.