This application describes an implantable device for tissue repair comprising at least two fabrics with interconnecting spacer elements transversing, connecting, and separating the fabrics, forming the device. Some embodiments have fixation points which can be an extension of at least one of the fabrics. The implantable device allows modification of the two fabrics having varying constructions, chemistries, and physical properties. The spacer elements create a space between the two fabrics, which can be used for the loading of biological materials (peptides, proteins, cells, tissues), offer compression resistance (i.e. stiffness), and compression recovery (i.e., return to original dimensions) following deformation and removal of deforming load. The inclusive fixation points of the fabrics are designed to allow for fine adjustment of the sizing and tension of the device to promote integration with the surrounding tissues as well as maximize the compressive resistance. The fixation points can include either the first fabric, the second fabric, or the combination of both fabrics. This device is suitable for soft and hard tissue regeneration or replacement with a preference for musculoskeletal tissues including but not limited to cartilage (including hyaline (referred to as articular; e.g. cartilage on the ends of long bones), fibrous (e.g. meniscus or intervertebral discs), elastic (e.g. ear, epiglottis)), bone, muscle, tendon, ligament, and fat.

Embodiments of an artificial meniscus implant are disclosed herein. An artificial meniscus includes at least one circumferential fiber and at least one non-circumferential fiber embedded within an arc-shaped body. The non-circumferential fibers may form loops extending through a peripheral edge of the implant, and the circumferential fibers may extend out of anterior and posterior horns of the implant to terminate in ends that are configured for fixation to bone. The ends may be interconnected, and covered by horn extensions to protect the ends from wear at the bone interface. Methods of making and implanting artificial meniscus are also disclosed herein. The method of making includes stepwise molding, layering, and curing of polymer material around the circumferential fibers and sewing the non-circumferential fibers into the polymer material. Methods of implanting may include threading ends of circumferential fibers through first and second bone tunnels.

A method for fabricating a resorbable scaffold for regeneration of meniscal tissue is disclosed. The method includes fabricating a polymer filament network using 3D printing in accordance with a digital model of the polymer filament network, such that the polymer filament network will include a first plurality of layers comprising the circumferentially-oriented filaments alternating with a second plurality of layers comprising the radially-oriented filaments, the polymer filament network having a three-dimensional shape and geometry between a first layer and a second layer which is substantially the same as a three-dimensional shape and geometry of the resorbable scaffold.

Embodiments of an artificial meniscus implant are disclosed herein. An artificial meniscus includes at least one circumferential fiber and at least one non-circumferential fiber embedded within an arc-shaped body. The non-circumferential fibers may form loops extending through a peripheral edge of the implant, and the circumferential fibers may extend out of anterior and posterior horns of the implant to terminate in ends that are configured for fixation to bone. The ends may be interconnected, and covered by horn extensions to protect the ends from wear at the bone interface. Methods of making and implanting artificial meniscus are also disclosed herein. The method of making includes stepwise molding, layering, and curing of polymer material around the circumferential fibers and sewing the non-circumferential fibers into the polymer material. Methods of implanting may include threading ends of circumferential fibers through first and second bone tunnels.