Injectable bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

A trapeziometacarpal joint implant includes a body defining a median plane, a metacarpal joint surface, and a trapezium joint surface. A first central region of the metacarpal joint surface is situated on an opposite side of the median plane from a second central region of the trapezium joint surface. The first and second central regions correspond to profiles of a first axial segment and a second axial segment, respectively. The first and second axial segments are one of a cylinder, a cone and a torus and are centered on a first axis and a second axis, respectively, where the first and second axes, as projected on the median plane, are substantially perpendicular to each other.

A bone graft delivery kit includes a hollow tube having a proximal end and a distal end. The hollow tube is configured to convey graft material to a graft receiving area in a patient. The hollow tube can be connected to an implant. The kit further includes a plunger to facilitate moving the graft material through the hollow tube.

The invention discloses a support element for humeral implant comprising a central body extending along an axis and at least three arms extending outwardly from the central body, the arms being transversal to said axis and bearing a ring element at their ends opposite to said central body, wherein at least a first and a second pair of arms form different angles.

The present disclosure is directed to composite bone grafts and to methods for providing such grafts for orthopedic and other surgical uses in a subject in need thereof. In some embodiments, the present disclosure provides a method for producing a composite bone graft, the method comprising, for example, the steps of: (i) selecting at least one donor site on at least one subject; (ii) removing at least one piece of bone, comprising cortical bone, from the at least one donor site; (iii) machining the at least one piece of bone to produce at least two bone components, each having a surface comprising at least one of a protuberance and a recess thereon; and (iv) joining the at least two machined bone components to produce a composite bone graft.

One aspect of the present disclosure relates to a tissue integration device. The tissue integration device can be produced by forming a polymer mixture into a shape. The polymer mixture can include a polymer resin and a growth-promoting medium. Next, at least one polymer forming the polymer resin can be oriented in at least one direction. The shaped polymeric material can then be formed into the tissue integration device.

Spinal spacing implants, spinal spacer assembly, expander and insertion instruments, kits and methods of assembly and use are disclosed. The spinal implant replacement instrument kit including a distraction instrument, a spacer inserter, and a spinal implant. A distraction instrument includes a first inserter member, a second inserter member, a first arm coupled to the first inserter member, a second arm coupled to the second inserter member, a distraction system coupled to the first arm and second arm, a first handle coupled to the first arm and the distraction system, and a second handle coupled to the second arm and the distraction system. Spinal spacing implants, spinal spacer assemblies, and methods of assembling and using the implants assemblies, and instruments are also disclosed.

The invention is directed to producing a shaped cartilage matrix isolated from a human or animal where the cartilage has been crafted to facilitate disinfection, cleaning, devitalization, recellularization, and/or integration after implantation. The invention relates to a process for repairing a cartilage defect and implantation of a cartilage graft into a human or animal by crafting the cartilage matrix into individual grafts, disinfecting and cleaning the cartilage graft, applying a pretreatment solution to the cartilage graft, removing cellular debris using an extracting solution to produce a devitalized cartilage graft, implanting the cartilage graft into the cartilage defect with or without an insertion device, and sealing the implanted cartilage graft with recipient tissue. The devitalized cartilage graft is optionally recellularized in vitro, in vivo, or in situ with viable cells to render the tissue vital before or after the implantation. The devitalized cartilage graft is also optionally stored between the removing cellular debris and the recellularizing steps.

An expandable intervertebral spacer includes a body, a proximal end, and a distal end. The body includes quadrants that form a substantially cylindrical shape in a first configuration and a substantially cuboidal shape in a second configuration. Each quadrant includes a ramp portion with a ramp and a landing and a sliding portion with a sliding side and a foot. The ramp portion of a first quadrant engages the sliding portion of a second quadrant. The proximal end and the distal end couple with the plurality of quadrants and transfer an actuating force to expand the body from the first configuration to the second configuration.

The invention concerns an arthrodesis implant (1) allowing promoting the bone fusion of two bones, said implant (1) comprising: a rigid and non-deformable anchoring body (4), designed to ensure the anchoring of the implant (1) in a first bone (2), a deformable portion (5) designed to ensure the anchoring of the implant (1) in a second bone, said deformable portion (5) comprising at least two anchoring arms (9, 10) which protrude beyond the anchoring body (4) from the base end (7) of the latter, the anchoring arms (9, 10) being separated from each other by a free space (E) so as to be able to be brought closer to each other by deformation of said anchoring arms under the action of the second bone. and being characterized in that at least one of the anchoring arms (9, 10) is provided with a longitudinal reinforcing fin protruding beyond the anchoring arm (9, 10) from a lateral side (20) of the latter. Osteosynthesis surgical implants.