An implant for treating a bone defect wherein the implant comprises osteoconductive supporting bodies and an insertion aid. The insertion aid is designed for insertion of the osteoconductive supporting bodies into a bone defect and for holding together the osteoconductive supporting bodies. Also disclosed is a kit comprised of an implant for treating a bone defect.

A delivery device includes a guide tool and an impact tool. The guide tool includes an elongate body formed with a longitudinal guide channel, whose inner perimeter is made to complement an outer contour of an implant. The elongate body is formed with a longitudinal impact-tool channel, whose inner perimeter is made to complement an outer contour of the impact tool.

A medical implant (1) designed to enable bony fusion between a first bone (20) and a second bone (21), said implant being in the form of an elongate part comprising, extending along the longitudinal axis of the part, a head (2) and a body (3) spaced apart from each other by a connection zone (4) connecting the head (2) to the body (3), said head (2) being suitable for being inserted into the first bone (20), said body (3) being suitable for being inserted into the second bone (21), said body (3) being a hollow body that is slotted longitudinally along at least a portion of its length in order to define at least three elastically deformable longitudinal tabs (5) by means of which said body (3) is suitable for being inserted into the second bone (21).

Each longitudinal tab (5) of the body (3) is an arcuate tab (5) that presents an outer face (6), i.e. directed towards the outside of the body (3), extending longitudinally in curved manner with curvature having its concave side directed towards the outside of the body (3).

A 3-dimensional block type bone graft includes a plurality of first channels extending horizontally in forward and backward directions and arranged at a predetermined interval in left and right directions and upward and downward directions, a plurality of second channels extending horizontally in the left and right directions and arranged at a predetermined interval in the forward and backward directions and the upward and downward directions, and a plurality of third channels extending vertically in the upward and downward directions and arranged at a predetermined interval in the forward and backward directions and the left and right directions, wherein the first channels, the second channels, and the third channels intersect perpendicularly to each other to communicate with each other so that the first channels, the second channels, and the third channels are configured in a 3-dimensional shape.

Particulate alloplastic bone replacement material and methods have a multitude of particles, wherein the particles have a core and at least six pins extending from the core, wherein the pins each have at least one connecting element, and wherein the pins are deformable elastically such that, upon multiple particles being pressed together, the connecting elements of different particles interlock with and/or snap into each other and the particles that are interlocked with and/or snapped into each other form an open-pored body of particles that are interlocked with and/or snapped into each other.

Bone particle compositions and kits are provided that include a biologically-resorbable cement and a plurality of processed bone particles. A first portion of the processed bone particles in the compositions have a shape configured to interconnect with one another, while a second portion of the processed bone particles having an irregular shape. Methods for treating a bone defect are also provided wherein an effective amount of the bone particle compositions are administered to a site of a bone defect in a subject.

A bone replacement material having reinforcing elements and a modelable mass which is curable on contact with water or an aqueous liquid as well as a process for producing a bone replacement material, to a further bone replacement material and to medical kits for treatment of bone defects.

A bone implant includes a body having a porous structure and having a size and shape configured for fitting to a bone, preferably in a bone defect. The porous structure is comprised of regularly arranged elementary cells whose interior spaces form interconnected pores, the elementary cells are formed by basic elements arranged in layers, wherein the basic elements are shaped like tetrapods, the tetrapods in each layer being arranged in parallel orientation and being positioned in-layer rotated with respect to tetrapods of an adjacent layer. The layers with rotated and non-rotated tetrapods are alternatingly arranged. Thereby a porous structure can be achieved which features improved mechanical characteristics, leading to improved biocompatibility.

A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of spaced apart walls comprising a biodegradable polymeric material (e.g., polycaprolactone); an osteoconductive mineral coating (e.g., a calcium compound) on at least a portion of the walls; and a bioactive agent (e.g., a bone morphogenetic protein) associated with the polymeric material and/or the coating. The bioactive agent is present in amount that induces ossification between the bones or adjacent bone surfaces. The cage may also include a fixation plate connected to at least one of the walls.

A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient. A method of 3D printing nitinol to create a patient-specific device to facilitate the establishment of a normal stress-strain trajectory in grafted bone.