Particulate alloplastic bone replacement material and methods have a multitude of particles, wherein the particles have a core and at least six pins extending from the core, wherein the pins each have at least one connecting element, and wherein the pins are deformable elastically such that, upon multiple particles being pressed together, the connecting elements of different particles interlock with and/or snap into each other and the particles that are interlocked with and/or snapped into each other form an open-pored body of particles that are interlocked with and/or snapped into each other.

An expandable implant for inserting within a skeletal space is provided, and a method for using the implant to expand the skeletal space. The implant is preferably designed to be inserted into an intervertebral space to replace at least part of an intervertebral disc between adjacent vertebral bodies. The expandable implant contains at least one first expansion compartment and at least one second expansion compartments, which compartments can be inflatable balloons that are inflated by a catheter. Inflating the first expansion compartment expands the implant in a first direction and inflating the second expansion compartment expands the implant in a second direction.

The invention in certain aspects relates to a surgical fastener for fastening tissue segments having tissue surfaces. The fastener includes a first fastener member having a base and a piercing element connected to the base for piercing the tissue segments to be fastened, a second fastener member having an opening for receiving and retaining the piercing element of the first fastener member such that the tissue segments to be fastened are retained between the first and second fastening members, and means for promoting adhesion between the tissue surfaces. The invention also relates to related methods and devices for promoting adhesion of tissue segments and preventing fastener migration, especially in an endoscopic procedure for the treatment of GERD.

An implant for performing interbody fusion within a human spine, inserters for such an implant, and associated methodology. The implant is preferably formed in situ from at least two separate but lockable members (a base member and a closure member). The base member may be implanted into an interbody space first, after which the end plates may be finally prepared and the base member packed with fusion promoting substances before engaging and locking the closure member. The closure member provides structural support for the adjacent vertebral bodies (along with the base member) and may be selected after implantation of the base member having a specific length, width, height, taper, etc. . . . to ensure an optimal sizing of the implant for desired restoration of disc height, coronal taper, sagittal taper, etc. . . .

An implant for spinal fusion includes a base member, a closure member, pins, and recesses. The base member includes a U-shaped configuration with an open end defined by first and second free ends of first and second side walls extending away from an end wall. The closure member is configured to form an enclosed interior when coupled with the base member. The closure member includes first and second overlapping portions configured to engage the first and second free ends. First and second pins are embedded in a respective one of the first and second free ends. First and second recesses are formed in a respective one of the first and second overlapping portions. The pins cooperate with the recesses to align and frictionally couple the base member with the closure member.

Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Planar alloplastic bone replacement material and methods comprise at least one plate for augmentation of bone defects, whereby the bone replacement material consists of a biocompatible plastic material, a biocompatible metal and/or a biocompatible metal alloy, whereby the at least one plate comprises a planar structure and comprises a plurality of pins extending outwards from the planar structure of the at least one plate, whereby the pins each comprise at least one connecting element, whereby the pins are deformable elastically and are arranged sufficiently close to each other such that pressing the surfaces of multiple plates onto each other causes the connecting elements of different plates to interlock with and/or snap into each other and the mutually interlocked and/or snapped-in plates form an open-pored body of mutually interlocked and/or snapped-in plates.

Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.