Prosthetic device suitable for being implanted in a bone or joint site of the human body, including a prosthetic body, wherein the prosthetic device includes or can be added with antibiotic or a medical substance.

The present invention is directed to a medical implant, methods of use and making of such implants. A method of making an implantable device may include obtaining an anatomical model in a computer aided design (CAD) system, customizing the anatomical model per patient specific parameters and creating a virtual image of the anatomical model, incorporating at least one microchannel geometry within said anatomical model, adjusting the density infill to a measurement ranging per patient specific parameters, and using three-dimensional printing to form the implantable device based on the anatomical model. The implant can be made of suitable metallic or polymeric material, such as PLA.

The invention relates to a hip joint prosthesis comprising a shaft-like section that can be inserted into a femur, and a proximally arranged end cap assembly which closes a hollow space of the hip joint prosthesis. According to the invention the end cap assembly carries a coil assembly that is connected to a first electrode with a first pole and to a second electrode with a second pole. The first and the second electrodes enclose surfaces of the hip joint prosthesis, and in a state in which the end cap assembly closes the hollow space of the hip joint prosthesis, the coil assembly is predominantly arranged in the hollow space.

A patient specific mega spacer (1, 2) for the patients having severe bone loss resulted from both of malignant and benign tumours, infection of the primary implant, or factures and severe bone loss due to trauma. The spacer was designed to fit the bone shape and anatomy based on the images captured from the CT-scan, x-ray MRI and/or ultrasound. The spacer designed with specific shape to maintain the gap and treat the infection by using a mix of antibiotics stored in reservoir (12) inside the spacer body and released with certain rate based on the medical needs. The assembly and the mechanism of the space will fit the original range of motion and recover the bone loss. The spacer manufactured by 3D printing with accredited biomaterials Nylon PA2200 to be implanted into the patient body.

Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.

An orthopedic system for delivery of a therapeutic agent to a bone includes an elongate stem adapted to be inserted into an intramedullary canal, an inlet configured to receive the therapeutic agent, and one or more outlets configured to deliver the therapeutic agent to the bone. The elongate stem may comprise one or more protrusions to engage the bone, and one or more channels extending longitudinally therein, fluidly coupled to the inlet. The therapeutic agent flows from the inlet through the one or more channels and exits into the intramedullary canal through the one or more outlets. The system may be configured to allow one or more dimensions of the system to be adjusted to accommodate the anatomy of a patient.

Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.

A temporary disposable spacer device implantable in the human body for treatment of an infected bone seat or a joint seat includes a body provided with at least one coupling surface to the bone seat or joint seat to be treated and recesses along the coupling surface.

An orthopaedic implant includes an internal fixation device. The internal fixation device includes: an exterior surface; a threaded section including a reservoir and at least one threaded section channel fluidly communicating the reservoir with the exterior surface, each threaded section channel having an interior diameter and a length which is greater than the interior diameter; a head including a head channel fluidly communicating the reservoir with an exterior surface of the head, a channel diameter of the head channel being respectively larger than a largest interior diameter of each threaded section channel, the channel diameter of the head channel being the same as a large interior diameter of the reservoir; and a continuously tapering inner surface between the head channel and the reservoir.

An antibiotic delivery system including an intramedullary stem that is adapted to be removably mounted into a medullary canal of a bone. The stem includes a body having an inlet adapted to be in fluid communication with a source of liquid-borne antibiotic and a plurality of outlets disposed along the stem. A channel extends between the inlet and the plurality of outlets for delivering a fluid-borne antibiotic from the inlet to the plurality of outlets so as to distribute the antibiotic along the medullary canal in a controlled fashion. A method of treating an infected joint during a two-stage re-implantation of an orthopedic implant is also disclosed.