An implant comprising a porous microstructure is disclosed which has an external surface, where at least a region of the external surface is formed of the porous microstructure. The microstructure is defined by at least one lattice of cells. Each cell has a predetermined cell topology and a plurality of edges. One or more of the edges of each cell connect to an adjacent cell along a corresponding edge thereof. Collectively, the cells have a periodic or aperiodic arrangement within the at least one lattice.

A method of manufacturing a femoral stem for a hip implant includes forming a femoral neck extending from a proximal end of the femoral stem towards a distal end of the femoral stem, forming an upper section connected to and extending from the femoral neck towards the distal end of the femoral stem, and forming a lower section connected to and extending from the upper section to the distal end of the femoral stem. Further, a method for designing a femoral stem for a hip implant includes generating a customized femoral stem model to match an information of a patient, generating at least one proximal-distal solid rib in the upper section, calculating density and stress distributions for an open lattice and for a closed lattice, and selecting a unit cell type and a pore size for the open lattice and the closed lattice to match a density and/or a stiffness of the patient's femur.

A hip/shoulder prosthesis includes: a head component; a metaphyseal component; a diaphyseal nail, and a locking device. The head component includes: a front face and rear face; with a bore, and first and second shaped recesses in the rear face. The metaphyseal component includes: a central transverse aperture at an angle to the metaphyseal component's axis; a first end configured for threaded engagement within the bore of the head component; and a longitudinal hole that begins at the second end, transects the transverse aperture and reaches the first end, to receive the locking device. The diaphyseal nail is inserted in the femoral or humeral canal, and includes: fastening apertures that receive corresponding screws for fastening the diaphyseal nail to the femur or humerus; a portion configured to be received within, and engage, the transverse aperture of the metaphyseal component, and a transverse hole configured to receive the locking device.

An assembly for attachment to a first implant component has a size and shape of a second implant component to be implanted together with the first implant component. The assembly includes a first body including a plug having a projection, and a second body including a recess having an internal surface defining at least one indentation. In a temporary configuration, when the plug is disposed within the recess and the projection is disposed at least partially within one of the at least one indentations, the first and second bodies are removably connected such that the first and second bodies are prevented from separating. A method of assembling the assembly includes removably connecting the plug of the first body into the recess of the second body by locating the projection within an indentation, such that the bodies are prevented from separating, and positioning the assembly on the first implant component.

Particular aspects provide novel devices for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior macroporous structure in which porosity may vary from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device suitable for bone tissue engineering in a recipient subject. In certain aspects, the device further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless and the growth of cells extending from the surface region inward is promoted.

The invention relates to a revision prosthesis shaft of a revision joint endoprosthesis for anchoring in an elongate bone (9), in particular femur. The surface is designed for adhesive agent-free fastening in the proximal epimetaphysis (91) and the diaphysis (92) of the bone. According to the invention, a distal epimetaphyseal extension (2) is provided at the far end of the shaft (12), the tip of which extension reaches into the distal epimetaphysis (93) of the bone. The extension (2) is designed for fastening in the distal epimetaphysis (93) by means of an adhesive agent (3), in particular bone cement. The invention combines the advantages of cement-free fastening, namely of the shaft in itself in the diaphysis (92), with the advantages of cemented fastening, namely of the extension in the distal epimetaphysis (93). Even in difficult cases in which sufficient hold previously could not be achieved for lack of fastening distance in the diaphysis, stable anchoring can thus be achieved. This increases the safety and longevity of the revision. The invention further relates to a corresponding implantation method.

An implant or endoprosthesis suitable to be implanted in human or animal tissue includes two (or more than two) parts to be joined in situ. Each one of the parts includes a joining location, the two joining locations facing each other when the device parts are positioned for being joined together, wherein one of the joining locations includes a material which is liquefiable by mechanical vibration and the other one of the joining locations includes a material which is not liquefiable by mechanical vibration and a structure (e.g. undercut cavities or protrusions) suitable for forming a positive fit connection with the liquefiable material. The joining process is effected by pressing the two device parts against each other and by applying ultrasonic vibration to one of the device parts when the two parts are positioned relative to each other such that the two joining locations are in contact with each other.

An implant or endoprosthesis suitable to be implanted in human or animal tissue includes two (or more than two) parts to be joined in situ. Each one of the parts includes a joining location, the two joining locations facing each other when the device parts are positioned for being joined together, wherein one of the joining locations includes a material which is liquefiable by mechanical vibration and the other one of the joining locations includes a material which is not liquefiable by mechanical vibration and a structure (e.g. undercut cavities or protrusions) suitable for forming a positive fit connection with the liquefiable material. The joining process is effected by pressing the two device parts against each other and by applying ultrasonic vibration to one of the device parts when the two parts are positioned relative to each other such that the two joining locations are in contact with each other.

A method of manufacturing a femoral stem for a hip implant includes forming a femoral neck extending from a proximal end of the femoral stem towards a distal end of the femoral stem, forming an upper section connected to and extending from the femoral neck towards the distal end of the femoral stem, and forming a lower section connected to and extending from the upper section to the distal end of the femoral stem. Further, a method for designing a femoral stem for a hip implant includes generating a customized femoral stem model to match an information of a patient, generating at least one proximal-distal solid rib in the upper section, calculating density and stress distributions for an open lattice and for a closed lattice, and selecting a unit cell type and a pore size for the open lattice and the closed lattice to match a density and/or a stiffness of the patient's femur.

A hip stem prosthesis is provided for treating a deficient hip joint.