Methods of implanting a device in the lumen of a blood vessel are described. The method includes providing a microcatheter and a device. The device includes a first hub, a second hub, a support structure including a plurality of struts disposed between the first hub and the second hub, and a layer of material disposed over the plurality of struts. The support structure has a low profile, radially constrained state with an elongated tubular configuration suitable for delivery from a microcatheter. The support structure also has an expanded state, a smooth outer surface, and has an axially shortened configuration relative to the radially constrained state. The microcatheter is advanced to a region of interest within the blood vessel. The support structure is advanced through the lumen of and out the distal end of the microcatheter where it expands to the expanded state.

Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

An intragastric device including (1) a first wire mesh structure having a pre-deployment shape, a post-deployment shape greater than the pre-deployment state, and one or more openings on an upper portion of the first wire mesh structure that are configured to permit food to enter the device, (2) a second wire mesh structure having a pre-deployment shape a post-deployment shape greater than the pre-deployment state, and one or more openings on a lower portion of the second wire mesh structure that are configured to permit food to exit the device. A sleeve may be coupled to the lower portion of the wire mesh structure. An anti-migration collar may interconnect the wire mesh structure and the sleeve. In use, food enters the upper portion of the first wire mesh structure, passes through both wire mesh structures, and then exits the lower portion of the second wire mesh structure.

The stent having self-expandability, the stent including: a body part formed in a tubular shape by a wire; and a first locking part and a second locking part protruding outward in a radial direction of the body part and formed by the wire. A first angle formed by a protrusion direction of the first locking part and an axial direction of the body part is different from a second angle formed by a protrusion direction of the second locking part and the axial direction.

Methods, systems, devices and apparatuses to support the walls of one or more blood vessels and perfuse blood through the one or more blood vessels. The stent device allows perfusion through one or more vessels. The stent device includes a tubular member. The tubular member has a single body that includes a main body lumen, a bypass lumen and one or more branch lumens. The tubular member is configured to be inserted into the aorta. The main body lumen is configured to expand and support a vessel wall of the aorta and the one or more branch lumens are configured to connect to one or more extension grafts that extend within one or more branch vessels. The stent device includes multiple rings of stents. The multiple rings of stents are positioned within the tubular member and are configured to be expandable to expand the tubular member to support the tubular member against the vessel walls.

A stent includes wavy-line pattern bodies having a wavy-line pattern and arranged side-by-side in an axial direction LD, and coiled elements arranged between the wavy-line pattern bodies adjacent and extending in a spiral manner around an axis. All apices on opposite sides of the wavy-line pattern of the wavy-line pattern bodies that are adjacent are connected by way of the coiled element. When viewing in a radial direction RD, a circular direction CD of the wavy-line pattern bodies is inclined with respect to the radial direction RD, and a winding direction of one of the coiled elements located at one side in the axial direction LD with respect to the wavy-line pattern bodies and a winding direction of one other of the coiled elements located at the other side in the axial direction LD are opposite.

Expandable introducer sheaths and associated laser cut frames for the insertion of a medical device into a blood vessel. In some examples, an expandable sheath may have a frame including a plurality of radial expansion bands and a plurality of connecting bridges for connecting adjacent radial expansion bands. The radial expansion bands are configured to accommodate radial expansion and the plurality of connecting bridges are configured to be longitudinally expandable and to impart column strength as a medical device (e.g., an intracardiac heart pump) is passed through the sheath, such as during insertion or removal of the medical device.

A prosthetic heart valve can include a stent and a leaflet assembly mounted to the stent. The stent is formed by a plurality of struts and includes an inflow end and an outflow end. The stent is deformable from a radially compressed configuration to a radially expanded configuration. The plurality of struts forms a plurality of rows of cells. The plurality of rows of cells includes a row of inflow cells at the inflow end, a row of outflow cells at the outflow end, and a row of intermediate cells that follows the row of outflow cells towards the inflow end. Each inflow cell comprises an inflow free apex. Each outflow cell comprises an outflow free apex and extends along an axial direction of the stent up to an end of said row of intermediate cells that points towards the inflow end of the stent.

A handle for a prosthetic heart valve delivery apparatus includes a housing, a motorized mechanism, and a holding mechanism. The housing is configured to be hand-held by a user and includes a distal opening. The motorized mechanism is disposed within the housing and is configured to be releasably coupled to a proximal end portion of a first shaft of the prosthetic heart valve delivery apparatus. When actuated, the motorized mechanism is configured to rotate the first shaft relative to the housing. The holding mechanism is disposed inside the housing and is configured to engage a proximal end portion of a second shaft of the prosthetic heart valve delivery apparatus such that the second shaft is axially and rotationally fixed relative to the housing, and the first shaft extends through the second shaft.

A prosthetic heart valve can include a stent and a leaflet assembly mounted to the stent. The stent is formed by a plurality of struts and includes an inflow end and an outflow end. The stent is deformable from a radially compressed configuration to a radially expanded configuration. The plurality of struts forms a plurality of rows of cells. The plurality of rows of cells includes a row of inflow cells at the inflow end, a row of outflow cells at the outflow end, and a row of intermediate cells that follows the row of outflow cells towards the inflow end. Each inflow cell comprises an inflow free apex. Each outflow cell comprises an outflow free apex and extends along an axial direction of the stent up to an end of said row of intermediate cells that points towards the inflow end of the stent.