An absorbent article such as disposable diaper, training pant, and adult incontinence undergarment comprising an absorbent structure comprising superabsorbent polymer particles, the article being able to absorb and contain body exudates and having improved absorption properties and therefore being able to reduce leakage, especially at the first gush, i.e. when the article starts to be wetted.

A pulpless core is provided with flexibility for superabsorbent expansion by using elastic strands stretched and coupled to a nonwoven layer, and then relaxed partially to create receiving valleys (puckers) and the puckers are provided with superabsorbent polymer, and then a layer of nonwoven or acquisition film can be coupled on top of nonwoven/elastic/sap carrier layers to create an absorbent core laminate.

A method of making an absorbent structure is provided. The method contains the steps of placing a supporting sheet onto raised portions with a shape and dimensions corresponding to first and second channels, depositing absorbent material onto the supporting sheet, and applying a pressure to the supporting sheet of the absorbent structure, the pressure being applied selectively to the portions of the supporting sheet that correspond to the channels.

In some aspects, the present invention provides methods of treating a subject in need of treatment for neuropathic pain, the method comprising administering a compstatin analog to the subject. In some embodiments, the compstatin analog is administered parenterally, e.g., intravenously.

A disposable absorbent article may include a topsheet, a backsheet, an absorbent core disposed between the topsheet and the backsheet, and a leg gasketing system. The leg gasketing system may include an inner cuff and an outer cuff. The inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge.

The present invention is an absorbent structure comprising a fibrous matrix (110), meltfusionable material and superabsorbent polymer particles (140). The absorbent structure is bonded by a meltfusion bond point (200) pattern, which is preferably created by ultrasonic welding.

A disposable absorbent article may include a topsheet, a backsheet, an absorbent core disposed between the topsheet and the backsheet, and a leg gasketing system. The leg gasketing system may include an inner cuff and an outer cuff. The inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge.

A disposable absorbent article may include a topsheet, a backsheet, an absorbent core disposed between the topsheet and the backsheet, and a leg gasketing system. The leg gasketing system may include an inner cuff and an outer cuff. The inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge.

An absorbent article such as disposable diaper, training pant, and adult incontinence undergarment comprising superabsorbent polymer particles able to absorb and contain body exudates having improved absorption properties and, therefore, reduce leakage, especially at the first gush, i.e. when the article starts to be wetted.

An absorbent article such as disposable diaper, training pant, and adult incontinence undergarment comprising superabsorbent polymer particles able to absorb and contain body exudates having improved absorption properties and, therefore, reduce leakage, especially at the first gush, i.e. when the article starts to be wetted.