The invention is a needle valve comprising at least one hollow needle and a seat. The hollow needle is comprised of a smooth surfaced hollow shaft and a port adapted to allow fluid communication between the interior and the exterior of said needle located in the side of the shaft at the distal end close to the tip of said needle. The seat comprises at least one bore adapted to accommodate one of the at least one needles through it. The needle and the bore can move one relatively to the other and the bore is provided in, or is fitted with, resilient material such that the outer diameter of the needle is greater than the inner diameter of at least part of the bore. As a result the passage of the shaft of the needle in the bore creates a closely-matched shaft and sheath, which blocks the passage of fluid through the port.

The invention relates to a valve unit for a system for producing parenteral nutrition, in which unit a three-way valve is used for each pair of connections to a source container. The valve unit is a component that can be mounted on die system and removed again after use. The valve unit is in particular provided as an interchangeable disposable component.

Apparatus, systems, methods and articles are described to prepare and track medications and medication containers as they are prepared, administered to patients and, in some cases, disposed of. Information such as medication type, concentration, and volume are associated with medication containers during preparation and this information can later be consumed/utilized when administering the medication from a container to a patient. Disposing of any remaining medication can also be tracked.

A liquid medicine filling device includes a container mounting unit, a liquid delivery flow conduit, a ventilation flow conduit, a syringe, a connection flow conduit, a first flow path switching unit, and a second flow path switching unit. The first flow path switching unit may switch between a flow path for filling through which the syringe communicates with a liquid medicine container via the ventilation flow conduit and a flow path for air removal through which the syringe communicates with the connection flow conduit via the ventilation flow conduit. The second flow path switching unit may switch between a flow path for filling through which the liquid medicine container communicates with the liquid medicine storage unit via the liquid delivery flow conduit and a flow path for air removal through which the liquid medicine storage unit communicates with the connection flow conduit via the liquid delivery flow conduit.

Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container. Some embodiments of the device can include a motor and a controller for automatically actuating a plunger of the syringe to transfer the desired amount of fluid.

Fluid transfer systems are disclosed that can be configured to transfer precise amounts of fluid from a source container to a target container. The fluid transfer system can have multiple fluid transfer stations for transferring fluids into multiple target containers or for combining different types of fluids into a single target container to form a mixture. The fluid transfer system can include a pump and a destination sensor, such as a weight sensor. The fluid transfer system can be configured to flush remaining fluid out of a connector to reduce waste, using air or a flushing fluid.

A method for treating a medical condition of a patient with Alpha-2 Macroglobulin (?2M) molecules in an allogeneic or xenogeneic manner, the method includes: drawing whole blood from a donor, separating plasma containing ?2M molecules from other components of the whole blood; isolating the ?2M molecules from the other components of the plasma; and administering at least some of the isolated ?2M molecules to the patient via injection or inhalation, wherein the donor and the patient are different individuals.

Fluid transfer systems are disclosed that can be configured to transfer precise amounts of fluid from a source container to a target container. The fluid transfer system can have multiple fluid transfer stations for transferring fluids into multiple target containers or for combining different types of fluids into a single target container to form a mixture. The fluid transfer system can include a pump and a destination sensor, such as a weight sensor. The fluid transfer system can be configured to flush remaining fluid out of a connector to reduce waste, using air or a flushing fluid.

A cap for a fluid container includes: (i) a body, (ii) a first port, and (iii) a second port. The first port includes a first port housing with a first opening and an elastic first seal member accommodated in the first port housing and sealing the first opening. The second port includes a second port housing with a second opening and an elastic second seal member accommodated in the second port housing and sealing the second opening. The first seal member is formed as a pierceable septum. The outer surface of the first seal member is flush with an edge surface of the first opening. The second seal member includes a valve opening configured to provide a fluid-tight connection with a fluid manipulation device.

An infusion apparatus including a body having an infusion reservoir and one end of the body adapted to receive a pierceable end of a vial, a barrel rotatably disposed in an opposing end of the body and having an internal fluid chamber, and a plunger received in one end of the barrel, wherein the barrel rotates relative to the body between a first position allowing bi-directional fluid flow between the barrel and the vial, and a second position allowing bi-directional fluid flow between the barrel and the infusion reservoir, and wherein the plunger is movable relative to the barrel to control the bi-directional fluid flow between the barrel and the vial and the bi-directional fluid flow between the barrel and the infusion reservoir.