A61K9/2866

PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ACUTE TOOTH OR JAW PAIN
20170252346 · 2017-09-07 ·

The invention relates to a pharmaceutical composition for oral administration for the treatment of acute dental or jaw pain, containing ibuprofen, caffeine and at least one distintegrant.

PHARMACEUTICAL PREPARATION HAVING EXCELLENT DISSOLUTION PROPERTIES, CONTAINING ESOMEPRAZOLE AND SODIUM BICARBONATE
20220233514 · 2022-07-28 ·

The present invention relates to a pharmaceutical preparation comprising omeprazole, an enantiomer thereof or a pharmaceutically acceptable salt thereof, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention relates to a pharmaceutical preparation in which sodium bicarbonate is first disintegrated so as to raise pH, and then omeprazole is dissolved such that the release properties of an active ingredient are improved, and thus the dissolution pattern and bioavailability of a drug can be enhanced.

COMPOSITIONS OF FILM COATINGS FOR TABLETS WITH INCREASED GLOSS, METHOD FOR PRODUCTION THEREOF AND APPLICATION OF SAME

Compositions and procedures for applying pharmaceutical tablet coatings, recognized as film coating wherein it is possible to obtain a final product coated with brightness superior to that achievable with typical compositions. The main difference in the composition is in the inclusion of the product derived from isomaltulose, which is a mixture of 6-O-α-D-glucopyranosyl-D-mannitol dihydrate with 6-O-α-D-glucopyranosyl-D-sorbitol, known as Isomalt, combined with a variety of film-forming polymers such as ethylene glycol and polyvinyl alcohol copolymer, copovidone, polyvinyl alcohol, and cellulosic derivatives, wherein the process conditions are advantageous as it is possible to handle high concentrations of solids in their preparation and wider applying temperature ranges than normally recommended for film coatings.

EDIBLE IJ INK, TABLET, AND CAPSULE

An edible IJ ink that has good dispersion stability and printing resumability (intermission resumability), dries quickly, and provides good print quality (for example, prevents streaking), and to provide a tablet and a capsule including a printed part printed using the edible IJ ink, the edible IJ ink comprises water, titanium oxide, a dispersant, a wetting agent, and a water-soluble polysaccharide having a weight average molecular weight smaller than 10,000, and the dispersant includes at least one of sodium carboxymethyl cellulose, sodium alginate, and sodium carbonate.

SOLID DISPERSION FORMS OF RIFAXIMIN
20210401813 · 2021-12-30 ·

Provided herein are solid dispersions comprising rifaximin and pharmaceutical compositions and uses thereof.

Hypromellose acetate succinate powder excellent in dissolved state and production method thereof, and production methods for composition for solid dispersion, coating composition, drug-containing particle, and solid

Provided are HPMCAS powder having high solubility when dissolved in a solvent and being capable of suppressing generation of undissolved materials; and a method for producing the powder. More specifically, provided is hypromellose acetate succinate powder having an average ratio of L to D of from 2.0 to 3.0, wherein L and D mean maximum and minimum diameters of each particle, respectively. Also provided is a method for producing a hypromellose acetate succinate, comprising the steps of: dissolving hypromellose powder in a solvent, esterifying the dissolved hypromellose with succinic anhydride and acetic anhydride in the presence of a catalyst to obtain a reaction mixture, and mixing the reaction mixture with water to precipitate hypromellose acetate succinate, wherein the reaction mixture just before being mixed with the water has a viscosity of from 100 to 200 Pa.Math.s.

Controlled Release Dosage Form

The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to GABA.sub.B receptor agonist.

PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF

The present invention relates to certain SGLT-2 inhibitors for treating, preventing, protecting against and/or delaying the progression of chronic kidney disease in patients, for example patients with prediabetes, type 1 or type 2 diabetes mellitus.

COMPOSITIONS OF PROTEINS WITH DIPEPTIDES AS STABILISING AGENTS
20220226251 · 2022-07-21 ·

This invention relates pharmaceutical compositions comprising a protein as the active ingredient together with one or more dipeptides as stabilising agents, and optionally an enzyme inhibitor. The compositions are particularly useful for administration to the intestinal tract.

METHODS OF TREATING VIRALLY ASSOCIATED CANCERS WITH HISTONE DEACETYLASE INHIBITORS

Described herein are certain dosing schedules and amounts that effectively prevent and manage side effects associated with histone deacetylase inhibitor (HDACi) treatment. Optionally, these schedules and dosing regimens include treatment with an antiviral agent.