Patent classifications
A61K31/4745
COMBINATION THERAPY COMPRISING AN FGFR INHIBITOR AND A KRAS INHIBITOR
- Alejandro Amador Arjona ,
- Angela Abdollahi ,
- Margaret Favata ,
- Jonathan Rios-Doria ,
- Hui Wang ,
- Susan Wee ,
- Pei Gan ,
- Jeffrey C. Yang ,
- Yong Li ,
- Le Zhao ,
- Chunhong He ,
- Chunyin Marshall Law ,
- Wenyu Zhu ,
- Xiaozhao Wang ,
- Wenqing Yao ,
- Peter Niels Carlsen ,
- Fenglei Zhang ,
- Qinda Ye ,
- Matthew S. McCammant ,
- Rocco Policarpo ,
- Artem Shvartsbart ,
- Jeremy Roach ,
- Gia Hoang ,
- Bin Hu ,
- Gencheng Li ,
- Robert Susick ,
- Padmaja Polam ,
- Chao Qi ,
- Alexander Sokolsky ,
- Haolin Yin ,
- Chang Min
The present disclosure relates to methods of treating cancer by administering a compound, which is a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in combination with a Kirsten rat sarcoma (KRAS) inhibitor.
COMBINATION THERAPY COMPRISING AN FGFR INHIBITOR AND A KRAS INHIBITOR
- Alejandro Amador Arjona ,
- Angela Abdollahi ,
- Margaret Favata ,
- Jonathan Rios-Doria ,
- Hui Wang ,
- Susan Wee ,
- Pei Gan ,
- Jeffrey C. Yang ,
- Yong Li ,
- Le Zhao ,
- Chunhong He ,
- Chunyin Marshall Law ,
- Wenyu Zhu ,
- Xiaozhao Wang ,
- Wenqing Yao ,
- Peter Niels Carlsen ,
- Fenglei Zhang ,
- Qinda Ye ,
- Matthew S. McCammant ,
- Rocco Policarpo ,
- Artem Shvartsbart ,
- Jeremy Roach ,
- Gia Hoang ,
- Bin Hu ,
- Gencheng Li ,
- Robert Susick ,
- Padmaja Polam ,
- Chao Qi ,
- Alexander Sokolsky ,
- Haolin Yin ,
- Chang Min
The present disclosure relates to methods of treating cancer by administering a compound, which is a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in combination with a Kirsten rat sarcoma (KRAS) inhibitor.
COMBINATION THERAPY COMPRISING AN FGFR INHIBITOR AND A KRAS INHIBITOR
- Alejandro Amador Arjona ,
- Angela Abdollahi ,
- Margaret Favata ,
- Jonathan Rios-Doria ,
- Hui Wang ,
- Susan Wee ,
- Pei Gan ,
- Jeffrey C. Yang ,
- Yong Li ,
- Le Zhao ,
- Chunhong He ,
- Chunyin Marshall Law ,
- Wenyu Zhu ,
- Xiaozhao Wang ,
- Wenqing Yao ,
- Peter Niels Carlsen ,
- Fenglei Zhang ,
- Qinda Ye ,
- Matthew S. McCammant ,
- Rocco Policarpo ,
- Artem Shvartsbart ,
- Jeremy Roach ,
- Gia Hoang ,
- Bin Hu ,
- Gencheng Li ,
- Robert Susick ,
- Padmaja Polam ,
- Chao Qi ,
- Alexander Sokolsky ,
- Haolin Yin ,
- Chang Min
The present disclosure relates to methods of treating cancer by administering a compound, which is a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in combination with a Kirsten rat sarcoma (KRAS) inhibitor.
Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Anti-EGFR combinations for treating tumors
The present invention relates to therapeutic combinations and methods for treating cancers using combination therapy.
Anti-EGFR combinations for treating tumors
The present invention relates to therapeutic combinations and methods for treating cancers using combination therapy.
Treatment of gliomas using organonitro compound combination therapy
The invention provides therapeutic methods and kits for treating a glioma using a particular dosing regimen of the organonitro compound ABDNAZ, radiation therapy, and one of temozolomide, irinotecan, or bevacizumab.
Treatment of gliomas using organonitro compound combination therapy
The invention provides therapeutic methods and kits for treating a glioma using a particular dosing regimen of the organonitro compound ABDNAZ, radiation therapy, and one of temozolomide, irinotecan, or bevacizumab.
Recombinant EGFL7, EGFL7 antibodies, and uses thereof
The present disclosure relates to recombinant EGFL7, EGFL7 antibodies, and uses thereof.