A61K51/047

PET TRACERS FOR VISUALIZING GABAA GAMMA1 RECEPTORS

The present invention provides radiolabeled GABA.sub.A 1 positive allosteric modulators (PAM) that are useful for medical imaging.

Cholecystokinin B receptor targeting for imaging and therapy

Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.