A biological component collection system and a circuit internal pressure acquisition method are provided, which are capable of accurately measuring the circuit internal pressure. A centrifugal separation device of a blood component collection system has a first load detecting unit an internal pressure calculation unit that calculates an internal pressure using the load detected by the first load detecting unit and internal pressure calculation data. The internal pressure calculation unit performs a calculation reflecting a change in the internal pressure calculation data depending on temperature.

A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. The disposable cartridge includes pressure and fluid flow sensors for measuring the pressure and fluid flow in the dialysate flow path and blood flow path. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. Preferably, the disposable cartridge includes a filter for removing waste products from dialysate.

A method of removing blood from an extracorporeal blood circuit and/or a functional device, each of which is connectable or connected with a blood treatment apparatus for the purpose of a blood treatment of a patient, after concluding a blood treatment session, the method comprising operating a blood pump in a second conveying direction which is opposite to a first conveying direction of the blood pump which is customary during the blood treatment, and an arterial line section of the extracorporeal blood circuit is or will be connected with a venous line section of the extracorporeal blood circuit.

The present invention relates to a blood treatment cassette having a cassette body, embodied as a hard part, and a film, wherein the film is connected with the hard part and covers the hard part at least partially, wherein the hard part comprises at least one valve seat or valve section or one valve base of a valve, wherein the valve is embodied to take, in addition to a first, open position of the valve in which the valve base and the section of the film positioned above it do not touch each other, a second, closed position of the valve when applying force on the section of the film and wherein the valve base, in its longitudinal extension, comprises or is a non-straight section. The present invention also relates to a blood treatment apparatus connected with a blood treatment cassette.

An improved method for separating whole blood into components and collecting a desired blood component. The method allows a desired blood component to be subjected to centrifugal forces within a separator for prolonged periods of time, yielding a cleaner cut and higher yield of the desired blood component. Whole blood is drawn from a source and pumped into a separator, the undesired blood components are removed from the separator at rates so as to build up the desired blood component in the separator. The desired blood component is only removed after a predetermined amount of the desired blood component has built up in the separator. It is preferred that the desired blood component be buffy coat and that the method be used to perform photopheresis treatments. In another aspect, the invention is a method of performing a full photopheresis treatment to treat diseases in a reduced time, preferably less than about 70 minutes, and more preferably less than about 45 minutes.

A device for determining the access flow rate of a patient when connected to a blood treatment machine performs a measurement phase (40), in which the blood treatment machine is caused (41, 43) to operate in first and second operating states, wherein the second operating state at least differs from the first operating state by a change of flow direction of blood or treatment fluid through a dialyzer of the blood treatment machine. Based on sensor values representing a fluid property (42, 44) of the treatment fluid in the first and second operating states, the device computes (45) a measurement value of comparison parameter (e.g. a ratio or a difference) that compares treatment efficiency in the first operating state to treatment efficiency in the second operating state, and determines (46), based on the measurement value, an estimated value of the access flow rate.

The present invention relates to a method for removing a first fluid from a blood filter for the blood treatment of a patient and/or for removing blood from the blood filter after completing the blood treatment session. It further relates to a medical treatment apparatus having a control device with which a method for removing a first fluid from a blood filter is executable, a digital storage medium, and a computer program product.

A blood component collection cassette that can trap a foreign object such as a blood-coagulated clot from blood components to be returned to a blood donor and a manufacturing method of the blood component collection cassette are provided.

A sheet-shaped filter member (60) is arranged on a flow path (42) in a cassette main body (40) of a blood component collection cassette (28). A first tube (66) and a second tube (68) are arranged in the cassette main body (40). An inner space (51) of a filter housing unit (54a) is separated by the filter member (60) into a first space (51a) on the side of the first tube (66) and a second space (51b) on the side of the second tube (68).

A blood component collection cassette that can trap a substance where blood components coagulate by using a simple and economical configuration, and a manufacturing method of the blood component collection cassette are provided.

A blood component collection cassette (28) includes a cassette main body (40) where a flow path (42) is formed and is configured to be mountable to a centrifugal separation device (14). The cassette main body (40) has a first sheet (40a) and a second sheet (40b) which are formed of a soft material. The flow path (42) is formed between the first sheet (40a) and the second sheet (40b). A filter member (60) for trapping a substance where blood components coagulate is arranged on the flow path (42) in the cassette main body (40).

The hemodialysis system includes a closed loop dialysate flow path which includes a dialyzer and a reservoir for storing dialysate, and a closed loop blood flow path which passes through the dialyzer in the opposite direction as the dialysate flow path. In addition, the hemodialysis system includes pumps for pumping dialysate and blood through their respective flow paths, a flow sensor for measuring the flow rate of dialysate in the dialysate flow path, and a level sensor for measuring the level of dialysate in the dialysate reservoir. A processor is connected to the flow sensor, reservoir level sensor and pumps to provide a first closed loop control system including the processor, flow sensor and a first dialysate pump, and a second closed loop control system including the processor, level sensor and a second dialysate pump which enable the processor to initiate, monitor and maintain ultrafiltration.