The present invention provides a system (1) comprising: a pen injection device (10) holding a specific type of medicament and comprising a dose expelling mechanism and pen communication means (15), a mobile communication unit (30) comprising mobile communication means (35) adapted to communicate with the pen communication means (15), and a software application program configured to determine a recommended type of medicament to be delivered to a user based on information indicative of a physiological condition of the user, wherein the pen injection device (10) further comprises indication means which in a first state indicates that the dose expelling mechanism is to remain idle and in a second state indicates that the dose expelling mechanism is available for operation, and wherein the mobile communication unit (30) is configured to, via a communication from the mobile communication means (35) to the pen communication means (15), a) prompt a change of state of the indication means from the second state to the first state in response to the recommended type of medicament to be delivered differing from the specific type of medicament, and/or b) prompt a change of state of the indication means from the first state to the second state in response to the recommended type of medicament to be delivered corresponding to the specific type of medicament.

The present disclosure relates to an injection device for delivery of a liquid medicament including a housing, a cartridge having a tubular shaped barrel filled with a liquid medicament and sealed in a proximal direction by a piston displaceably arranged in the barrel, and a drive mechanism having a piston rod to advance in a distal direction against a proximally facing surface of the piston of the cartridge. The drive mechanism is configured to advance the piston rod in the distal direction by a distance z1 to dispense a reference volume V1 of the medicament when operably engaged with a reference cartridge having a reference diameter D1, and, the cartridge has a diameter D2 smaller than the reference diameter D1 to dispense a volume V2 of the medicament smaller than the reference volume V1 when the piston rod advances in distal direction by the distance z1.

Apparatus and methods for medicament delivery. The apparatus may include, and the methods may involve, a delivery device for delivering a target amount of the medicament from a distal end of the device. The device may include a rod for moving a plunger that discharges the medicament from the distal end. The device may avoid or reduce deformation of the plunger during the discharge. The plunger motion may be stopped by detent that interacts with the rod. The apparatus and the methods may provide an operator indication of progress of stages of operation. The device may feature triggers corresponding to stages of medicament displacement from the device, such as pre-delivery stages, including priming.

A displacement sensing device is configured for a peritoneal dialysis system. The peritoneal dialysis system includes a housing and a syringe. The syringe is disposed on the housing and has a push rod. The displacement sensing device includes a guide rod, a probing module, and a resistance scale. The guide rod is coupled to the push rod, and the probing module is disposed in the housing and is fixed at the guide rod. The resistance scale is disposed at a side of the probing module. The probing module is configured to contact the resistance scale to obtain a resistance value of the resistance scale and determine a displacement magnitude of the push rod. In addition, a peritoneal dialysis system is also mentioned.

A cartridge system for use with a drug delivery device (100), comprising: a pre-filled cartridge comprising: a) a cartridge body (210) accommodating a drug, b) a piston (250) slidably disposed in the cartridge body (210) and configured for providing a proximal seal, the piston (250) comprising: b1) a piston first member (260) comprising a first material and forming a distal end, a proximal end and a sealing periphery in contact with the cartridge body (210), wherein the distal end is in contact with the drug and wherein the proximal end of the piston first member (260) includes a proximally facing opening, and b2) a piston second member (270) comprising a material of lower compressibility compared to the first material, the piston second member (270) comprising a sleeve-formed portion arranged in the proximally facing opening of the piston first member (260), wherein the piston second member (270) comprises a proximally facing opening forming a socket; anda plug unit (280) coupleable or coupled into the socket of the piston second member (270), wherein the plug unit (280) comprises an electronic sensor unit (290) configured to determine the axial position of the piston (250) within the cartridge body (210) and wherein the plug unit (280) is at least partially received within the proximally facing opening of the piston first member (260).

Dosing device (1) for the dosage of blood compounds, medical treatments or other substances, comprising a stepped body (9) in a plunger (3) and a presser mechanism (17) in the tube (2) of a syringe. The projection (19) from the pusher (18) of the presser mechanism (17) transmits a downwards force (F) exerted by the user, onto the step (12) of the stepped body (9) by pushing it down a distance (x) with the plunger (3). In this way, the dosing device (1) can measure an exact dose of the compound manually, quickly and easily without the need for additional measurements.

Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.

A method and apparatus are provided for use in locating a target region which is situated in the body of a subject, for example for the delivery of drugs. The system includes an assembly for controlling the flow of fluid from a fluid reservoir to a conduit, such as a needle. A sensor detects a characteristic indicative of the fluid pressure in the conduit. The system processes data from the sensor to detect the presence of a pulsatile waveform. A controller may control further operation of the system based on information regarding the presence of the pulsatile waveform and features of the waveform, such as amplitude.

An add-on device for a drug delivery device comprises a camera for capturing an image of a scale drum, and a processor for determining the value of a captured image using a first image analysis process, the value corresponding to a set dose amount. If the determined value belongs to a pre-defined group of values, the determined value is confirmed using a second image analysis process in which for a given value from the pre-defined group of values one or more partial image areas and an associated nominal content thereof are pre-defined. If the captured content for each image area corresponds to the nominal content, the determined value is confirmed.

The present disclosure relates to a magnifying device attachable to an injection device. The magnifying device includes a frame having a distal end and having a proximal end opposite to the distal end and further has a receptacle extending from the distal end towards the proximal end. The receptacle is accessible from the distal end to receive a proximal end section of the injection device therein. A magnifying lens is fixed to the proximal end of the frame and extending at least partially across the proximal end of the frame.