An ambulatory infusion device including a pump drive unit, a valve drive unit and a control unit. The pump drive unit includes a pump actuator and a pump driver coupled to a piston of a metering pump unit. The valve drive unit includes a valve actuator and a valve driver coupled to a valve unit for transmitting a valve switching force or torque. The control unit controls a repeated execution of: (a) placing the valve unit in a filling state; (b) displacing the piston in a retraction direction; (c) displacing the piston in an advancing direction by a backlash compensation distance; (d) switching the valve unit from the filling state into a draining state; and (e) further displacing the piston in the advancing direction in a number of incremental steps over an extended time period.

A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

A computer-controlled injector for use with a medicament cartridge and including a housing having a medicament cartridge receiving volume and a medicament cartridge insertion and removal opening communicating with the medicament cartridge receiving volume; a pivot mount element mounted onto the housing for selectably enabling access to the medicament cartridge receiving volume via the opening; a mechanical latch selectably locking the pivot mount element in a closed operative orientation; and an injection drive mechanism including a computer-controlled motor for driving a piston, forming part of the medicament cartridge, for injecting a medicament, the computer-controlled motor also being operative for operating the mechanical latch.

A dosage verification system for use prior to administering an injection of a medicinal fluid drawn into a medical syringe, the system comprising a medical syringe having a barrel with an outwardly facing, flat indicia display surface, plunger having a plunger seal disposed inside and slidably engaging an inwardly facing wall of the barrel and a plunger handle projecting rearwardly from the barrel, and a hypodermic needle projecting forwardly from the barrel, all in combination with an imaging device configured to view and selectively capture, store or transmit a digital image of the plunger position relative to the barrel when a dose of the medicinal fluid is drawn into the fluid chamber of the barrel prior to an injection to verify and provide a record of the dosage drawn, and to alert a user prior to injection when an incorrect dosage is drawn into the fluid chamber of the syringe.

A dose setting mechanism for a medicament delivery device, which dose setting mechanism comprises, a tubular member 10 having a longitudinal track 18 of a predetermined length; a dose drum 40, coaxial with the tubular member 10, and being axially and rotationally movable relative to the tubular member 10; a stop member 90, axially movable but rotationally locked relative to the tubular member 10, and further being in an axially slaved connection with the dose drum 40; wherein said stop member 90 comprises a track follower 98 in engagement with the longitudinal track 18, such that rotational movement of the dose drum 40 relative to the tubular member 10 may cause a maximum axial displacement of said dose drum 40 and said stop member 90, relative to the tubular member 10, corresponding to said predetermined length.

A medical syringe plunger and a medical finger grip for a disposal syringe having both a dose accuracy function and a plunger pulling out prevention function are provided. A plunger rod includes a first guide groove for guiding the axial movement by a protrusion of a finger grip which extends toward the center of the hole of the finger grip and moves in it, a second guide groove formed at a position on the plunger rod which is rotated by a predetermined angle in the circumferential direction with respect to the first guide groove for guiding the axial movement, an axial direction movement restriction section formed in the vicinity of the end point of the first guide groove for restricting the protrusion's movement in the axial direction, and a protrusion transition section for enabling the protrusion to transit from the first guide groove to the second guide groove.

An auto-injector automatically dispenses a predetermined dose of medicament upon activation. The auto-injector includes a needle cover operative to engage an injection site and activate the injector. The needle cover is configured to move from a locked retracted position prior to a medicament dispensing operation to a locked extended position after the medicament dispensing operation. The non-removable needle cover prevents contact with the needle both before and after the medicament dispensing operation.

The present invention relates to a drug delivery device for setting and dispensing of a dose of a medicament is presented comprising a housing to accommodate a cartridge filled with the medicament, an electrically operated drive mechanism to be operably engaged with the cartridge to expel a predefined dose of the medicament from the cartridge, and at least one dose element displaceably arranged relative to the housing to set and/or to dispense the dose of the medicament, wherein the dose element and the drive mechanism are mechanically decoupled from each other.

A device for delivery of medicament is presented that has an elongated housing, a container mounted within the housing and adapted to contain liquid medicament, a stopper slidably arranged within said container, and a delivery mechanism comprising a resilient member, a plunger assembly having one end connected to the stopper and a second end being operably connected to the resilient member, a rotatable latch for releasably retaining the plunger assembly in a first position where the resilient member has an accumulated energy, where rotation of the latch releases the plunger assembly such that the accumulated energy is transferred to the plunger assembly for driving the stopper within the container whereby the medicament within said container is delivered to an injection site. After delivery of the medicament a rotator having a hard stop feature aligns with a rib on the protective shield to prevent retraction of the protective shield.

Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.